Journal
CIRUGIA ESPANOLA
Volume 89, Issue 3, Pages 152-158Publisher
ELSEVIER ESPANA SLU
DOI: 10.1016/j.ciresp.2010.12.005
Keywords
Colorectal neoplasia; Obesity; Body mass index; Prognostic factors; Survival
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Introduction: The long-term survival of patients operated on for colonic cancer depends on many factors. Obesity decreases the life expectancy of the general population who suffer from it, but it is not clear whether obesity, measured by the Body Mass Index (BMI), is a prognostic factor of survival for patients operated on for colonic cancer. Material and methods: The patients included in this study had TNM stage I, II y III, and were subjected to elective surgery for cancer of the colon in the Girona University Hospital between 1990 and 2001. The BMI was classified according to the WHO classification. A total of 38 different variables were studied using a bivariate analysis with BMI. A Cox model was subsequently constructed with the most clinically relevant parameters, and with those most strongly associated with survival in the bivariate analysis. Results: BMI was not associated with survival in the bivariate analysis. Neither did the multivariate analysis show that BMI was an independent prognostic factor of long-term survival in cancer of the colon without metastasis, but it did show that the TNM stage, ASA score, surgical technique, age at surgery, and the immune cell response were prognostic factors. Conclusions: The body mass index is not a prognostic factor of the long-term survival of patients with colonic cancer. (C) 2010 AEC. Published by Elsevier Espana, S.L. All rights reserved.
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