Article
Cardiac & Cardiovascular Systems
Marie de Bakker, Atul Anand, Martin Shipley, Takeshi Fujisawa, Anoop S. V. Shah, Isabella Kardys, Eric Boersma, Eric J. J. Brunner, Nicholas L. L. Mills, Dorien M. M. Kimenai
Summary: The study found that cardiac troponin concentrations are lower in women than men. The trajectory of cardiac troponin differs between sexes and is associated with cardiovascular outcomes, highlighting the importance of a sex-specific approach in cardiovascular risk prediction.
Review
Biochemistry & Molecular Biology
Giandomenico Bisaccia, Fabrizio Ricci, Mohammed Y. Khanji, Giulia Gaggi, Andrea Di Credico, Sabina Gallina, Angela Di Baldassarre, Barbara Ghinassi
Summary: High-sensitivity cardiac troponin assays are the gold standard for diagnosing myocardial injury, and using sex-specific thresholds can improve the accuracy of prognosis. However, the incremental diagnostic and prognostic value of different thresholds for men and women is debated. This review aims to summarize the current understanding of sex-based differences in cardiac troponin levels and reassess their clinical utility in cardiovascular disease risk assessment and prevention in women.
Article
Cardiac & Cardiovascular Systems
Alexander T. A. Sandhu, Paul A. Heidenreich, William A. Borden, Steven A. Farmer, P. Michael Ho, Gmerice C. Hammond, Janay C. K. Johnson, Rishi K. H. Wadhera, Jason H. Wasfy, Cathie Biga, Edwin D. Takahashi, Khamal D. E. Misra, Karen E. Joynt Maddox
Summary: Clinician payment is transitioning from fee-for-service to value-based payment, but the goals of improving healthcare quality and lowering costs have not been met. This policy statement reviews the current state of value-based payment and provides recommendations for future design and implementation.
Review
Biochemistry & Molecular Biology
Maria Raza Tokatli, Leuconoe Grazia Sisti, Eleonora Marziali, Lorenza Nachira, Maria Francesca Rossi, Carlotta Amantea, Umberto Moscato, Walter Malorni
Summary: This article provides a broad review of the role of hormone regulation in gender medicine and gender differences across key clinical areas. The study highlights the influence of sex differences in immune response, cardiovascular diseases, neurological disorders, cancer, and COVID-19. It also emphasizes the importance of gender implications in occupational health and health policy, calling for more personalized clinical medicine and public health approaches.
Article
Computer Science, Interdisciplinary Applications
J. M. Ordovas, D. Rios-Insua, A. Santos-Lozano, A. Lucia, A. Torres, A. Kosgodagan, J. M. Camacho
Summary: This study constructs a Bayesian network based on a large population database and expert judgment to explore the interrelations between cardiovascular risk factors. It emphasizes the predictive assessment of medical conditions and provides a computational tool to explore and hypothesize such interrelations.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Rubee Dev, Divine Favour-Ofili, Valeria Raparelli, Hassan Behlouli, Zahra Azizi, Karolina Kublickiene, Alexandra Kautzky-willer, Maria Trinidad Herrero, Louise Pilote, Colleen M. Norris
Summary: There is a rise in cardiovascular diseases in sub-Saharan Africa, and gender-related factors play a role in the development of these diseases. Females have higher prevalence rates of hypertension and overweight/obesity compared to males, resulting in poorer cardiovascular health for females.
Editorial Material
Multidisciplinary Sciences
Joanne Liu, Helen Clark, Michel Kazatchkine
Summary: Heads of state and government have the responsibility to prevent future pandemics.
Article
Cardiac & Cardiovascular Systems
Caitlin A. Moran, Lauren F. Collins, Nour Beydoun, Puja K. Mehta, Yetunde Fatade, Ijeoma Isiadinso, Tene T. Lewis, Brittany Weber, Jill Goldstein, Igho Ofotokun, Arshed Quyyumi, May Y. Choi, Kehmia Titanji, Cecile D. Lahiri
Summary: Immune responses differ between men and women, with women more prone to chronic autoimmune diseases. Current ASCVD risk assessment tools underestimate the risk in immune dysregulation populations, especially women. This review focuses on the impact of immune dysregulation on ASCVD and discusses factors contributing to ASCVD in women with immune disorders.
CIRCULATION RESEARCH
(2022)
Editorial Material
Multidisciplinary Sciences
Thekkumkara Surendran Anish
Summary: Repeated outbreaks raise the risk of a more efficient transmission of the Nipah virus strain.
Article
Public, Environmental & Occupational Health
Ricardas Radisauskas, Kawon Victoria Kim, Shannon Lange, Vaida Liutkute-Gumarov, Olga Mesceriakova-Veliuliene, Janina Petkeviciene, Mindaugas Stelemekas, Tadas Telksnys, Alexander Tran, Juergen Rehm
Summary: Between 2001 and 2018, Lithuania saw a decrease in cardiovascular disease mortality rates, with more prominent declines in women. The implementation of alcohol control policies appeared to align with the declining trend in alcoholic cardiomyopathy mortality rates.
Article
Cardiac & Cardiovascular Systems
Demilade A. Adedinsewo, Amy W. Pollak, Sabrina D. Phillips, Taryn L. Smith, Anna Svatikova, Sharonne N. Hayes, Sharon L. Mulvagh, Colleen Norris, Veronique L. Roger, Peter A. Noseworthy, Xiaoxi Yao, Rickey E. Carter
Summary: Cardiovascular disease remains the top cause of death in women, and there is an urgent need for more effective screening methods and preventive interventions. The use of massive data and technologies such as artificial intelligence can enable personalized screening and interventions for women.
CIRCULATION RESEARCH
(2022)
Review
Oncology
Federica Teglia, Giulia Collatuzzo, Paolo Boffetta
Summary: This narrative review provides new insights and reports the current state of knowledge on occupational cancers among women, with a focus on three female working categories: beauticians and hairdressers, farmers, and healthcare workers. The inclusion of women in occupational cancer studies has become more urgent and feasible due to the changing workforce and increasing number of women employed. The review also discusses the difficulties in evaluating occupational causes of female gynecologic tumors and the potential gender differences in outcome responses.
Article
Public, Environmental & Occupational Health
Lauren J. Tanz, Jennifer J. Stuart, Paige L. Williams, Eric B. Rimm, Stacey A. Missmer, Kenneth J. Mukamal, Kathryn M. Rexrode, Janet W. Rich-Edwards
Summary: The study evaluated the inclusion of preterm delivery and parity in CVD risk scores for improved identification of high-risk women, especially when they are young. The results showed some improvements in CVD risk prediction for women above 30 years old when considering preterm delivery and parity.
JOURNAL OF WOMENS HEALTH
(2021)
Article
Rheumatology
Tea Gegenava, Federico Fortuni, Nina Marijn van Leeuwen, Anders H. Tennoe, Anna-Maria Hoffmann-Vold, Ruxandra Jurcut, Adrian Giuca, Laura Groseanu, Felix Tanner, Oliver Distler, Jeroen J. Bax, Jeska De Vries-Bouwstra, Nina Ajmone Marsan
Summary: This study aimed to assess the impact of sex differences on cardiovascular outcomes in patients with systemic sclerosis (SSc). The results showed that male SSc patients had a higher incidence of cardiovascular events, and the adjusted left ventricular global longitudinal strain may explain this gender difference in outcomes.
Article
Cardiac & Cardiovascular Systems
Siyi Shangguan, Dariush Mozaffarian, Stephen Sy, Yujin Lee, Junxiu Liu, Parke E. Wilde, Andrea L. Sharkey, Erin A. Dowling, Matti Marklund, Shafika Abrahams-Gessel, Thomas A. Gaziano, Renata Micha
Summary: Implementing and achieving the US National Salt and Sugar Reduction Initiative's sugar reduction targets could prevent a significant number of cardiovascular disease and diabetes cases, while also resulting in substantial health gains and cost savings. The policy is particularly effective across different populations, with the greatest health gains seen among individuals with lower income and education levels.
Article
Health Care Sciences & Services
Aili Langford, Danijela Gnjidic, Chung-Wei Christine Lin, Lisa Bero, Jonathan Penm, Fiona M. Blyth, Carl R. Schneider
Summary: This study explored healthcare professional stakeholders' perspectives on the challenges associated with opioid deprescribing and factors to be considered in developing deprescribing guidelines. It found that healthcare professionals view opioid deprescribing as a complex and challenging practice with various barriers in clinical settings. They emphasized the need for evidence-based guidance and a multi-target, multimodal intervention strategy in prospective opioid deprescribing guidelines to address patient psychosocial factors.
BMJ QUALITY & SAFETY
(2021)
Article
Public, Environmental & Occupational Health
Zhaoli Dai, Cynthia M. Kroeger, Mark Lawrence, Gyorgy Scrinis, Lisa Bero
PUBLIC HEALTH NUTRITION
(2020)
Review
Medicine, General & Internal
Nicholas Chartres, Alice Fabbri, Sally McDonald, Joanna Diong, Joanne E. McKenzie, Lisa Bero
Article
Medicine, General & Internal
Lisa Parker, Quinn Grundy, Alice Fabbri, Barbara Mintzes, Lisa Bero
Summary: This study explores how patient groups receiving funding from pharmaceutical industry manage the risk of undue influence from their sponsors. Groups work to protect their credibility and autonomy by setting practical rules or 'lines in the sand' about industry funding activities. Transparency varies among groups, and there is little external guidance on responding to influence from funders.
Editorial Material
Environmental Sciences
Colin L. Soskolne, Shira Kramer, Juan Pablo Ramos-Bonilla, Daniele Mandrioli, Jennifer Sass, Michael Gochfeld, Carl F. Cranor, Shailesh Advani, Lisa A. Bero
Summary: Epidemiology plays a crucial role in understanding health and disease, but its methods and language can be manipulated and misused. A toolkit has been created to help professionals detect bias and flaws in scientific studies related to public health. It is important to address financial conflicts of interest and improper study design to ensure transparency and validity in epidemiological research.
ENVIRONMENTAL HEALTH
(2021)
Article
Medicine, General & Internal
Lisa Bero, Rosa Lawrence, Louis Leslie, Kellia Chiu, Sally McDonald, Matthew J. Page, Quinn Grundy, Lisa Parker, Stephanie Boughton, Jamie J. Kirkham, Robin Featherstone
Summary: The study found that COVID-19 preprints and subsequent journal publications were largely similar in reporting study characteristics, outcomes, and spin. It is important to critically evaluate all COVID-19 studies published as preprints and journal publications for discrepancies and spin.
Article
Medicine, General & Internal
Emily Aspasia Karanges, Conrad Nangla, Lisa Parker, Alice Fabbri, Cynthia Farquhar, Lisa Bero
Summary: The study investigated pharmaceutical industry payments related to fertility and assisted reproduction in Australia, revealing that pharmaceutical companies sponsored a range of fertility clinicians and organizations, potentially contributing to the overuse of fertility services.
Letter
Medicine, General & Internal
Barbara Mintzes, Alice Bhasale, Marc Torka, Ruth Lopert, Sallie-Anne Pearson, Joel Lexchin, Lisa Bero
INTERNAL MEDICINE JOURNAL
(2021)
Article
Health Care Sciences & Services
Raju Kanukula, Joanne E. McKenzie, Lisa Bero, Zhaoli Dai, Sally McDonald, Cynthia M. Kroeger, Elizabeth Korevaar, Matthew J. Page
Summary: This study aimed to investigate the frequency of encountering multiple results in systematic reviews of nutrition studies, as well as the specification of methods to select results. It found that a high percentage of reviews included in the study encountered multiplicity of results, suggesting the importance of specifying methods to handle multiplicity when designing reviews.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Liora Baram, Zhaoli Dai, Sally McDonald, Lisa A. Bero
Summary: This study found that disclosure of conflicts of interest (COI) was low in the evidence supporting bone health guidelines, and studies with missing or unclear COI disclosures were more likely to have favorable conclusions. There is a need for greater transparency regarding COI in bone health guidelines.
PUBLIC HEALTH NUTRITION
(2022)
Review
Health Care Sciences & Services
Elizabeth Korevaar, Amalia Karahalios, Simon L. Turner, Andrew B. Forbes, Monica Taljaard, Allen C. Cheng, Jeremy M. Grimshaw, Lisa Bero, Joanne E. McKenzie
Summary: This study aimed to examine the statistical approaches, methods, and completeness of reporting in reviews that meta-analyze results from interrupted time series (ITS). The results showed that although most reviews used two-stage meta-analysis and fitted random effects models, reporting of the statistical methods and ITS characteristics was often incomplete. The study suggests that improvement is needed in the conduct and reporting of these reviews.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Oncology
Adrian M. J. Pokorny, Ray Moynihan, Peter Fox, Deme J. Karikios, Lisa A. Bero, Barbara J. Mintzes
Summary: Australian cancer physicians frequently interact with the pharmaceutical industry, and those who have a positive attitude towards these interactions are likely to do so more often. Further research is needed to understand the motivations behind these interactions.
JCO ONCOLOGY PRACTICE
(2022)
Article
Public, Environmental & Occupational Health
Kellia Chiu, Anne Marie Thow, Lisa Bero
Summary: This study analyzes pharmacy policy changes and responses to COVID-19 to understand the expansion of pharmacists' scope of practice. The study finds that temporary measures introduced during the pandemic may become permanent, with increased responsibilities for pharmacists. The government's need to address crises and prioritize medication safety and access also provide opportunities for expansion. However, there are constraints such as potential permanent restrictions on pharmacists' practice, negative perceptions from other clinicians, and a lack of pharmacist representation in institutional structures.
RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY
(2022)
Editorial Material
Environmental Sciences
Colin L. Soskolne, Lisa A. Bero, Shira Kramer, Michael Gochfeld, Juan Pablo Ramos-Bonilla, Jennifer Sass, Carl F. Cranor, Shailesh Advani, Daniele Mandrioli
Summary: This study presents a Toolkit for detecting misused epidemiological methods and proposes suggestions for its modification. The suggestions include rearranging the Toolkit, expanding or adapting it to other disciplines, and using visual representation to assess the Toolkit items. The authors recommend incorporating the Toolkit into forensic epidemiology and its application in graduate training, continuing education, and conferences. Feedback from the research community is welcomed.
ENVIRONMENTAL HEALTH
(2022)
Article
Medicine, General & Internal
Adrian M. J. Pokorny, Lisa A. Bero, Peter Fox, Deme J. Karikios, Eliza J. McEwin, Ray Moynihan, Barbara Mintzes
Summary: This qualitative study aimed to understand how Australian cancer physicians interact with the pharmaceutical industry and why. The study identified six themes related to physicians' views and experiences of interactions, as well as the management of these interactions. These findings highlight the need for a balanced approach to industry interactions in cancer care.