Contribution of Impaired Mitochondrial Autophagy to Cardiac Aging

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

(2016) Angela V. Hafner et al.   Aging-US

Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans

(2014) Márton L. Tóth et al.   Autophagy

Resveratrol in cardiovascular health and disease

(2011) Goran Petrovski et al.   Annals of the New York Academy of Sciences

Titrating autophagy in cardiac plasticity

(2011) Dian J. Cao et al.   Autophagy

AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy

(2011) Zhonglin Xie et al.   Autophagy

Mitochondria removal by autophagy

(2011) Ke Wang et al.   Autophagy

Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum

(2011) Dalibor Mijaljica et al.   Autophagy

The role of oxidized cytochromecin regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia

(2011) Philippe Pasdois et al.   BIOCHEMICAL JOURNAL

Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy

(2011) E. D. Abel et al.   CARDIOVASCULAR RESEARCH

SNARE Proteins Are Required for Macroautophagy

(2011) Usha Nair et al.   CELL

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure

(2011) Dao-Fu Dai et al.   CIRCULATION RESEARCH

Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

(2011) Z. Xie et al.   DIABETES

Caloric Restriction Ameliorates Angiotensin II–Induced Mitochondrial Remodeling and Cardiac Hypertrophy

(2011) Piet Finckenberg et al.   HYPERTENSION

Signal Transduction by Mitochondrial Oxidants

(2011) Toren Finkel   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy in heart disease: A strong hypothesis for an untouched metabolic reserve

(2011) B. Loos et al.   MEDICAL HYPOTHESES

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

Ageing theories unified

(2011) Daniel P. Kelly   NATURE

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

(2010) Dao-Fu Dai et al.   AGING CELL

Autophagy in health and disease. 5. Mitophagy as a way of life

(2010) Roberta A. Gottlieb et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autophagy During Cardiac Stress: Joys and Frustrations of Autophagy

(2010) Roberta A. Gottlieb et al.   Annual Review of Physiology

Mitophagy Selectively Degrades Individual Damaged Mitochondria After Photoirradiation

(2010) Insil Kim et al.   ANTIOXIDANTS & REDOX SIGNALING

Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells

(2010) Raquel S. Carreira et al.   Autophagy

Role of selective autophagy in cellular remodeling

(2010) Pavan Kadandale et al.   Autophagy

Inhibition of autophagy in the heart induces age-related cardiomyopathy

(2010) Manabu Taneike et al.   Autophagy

What are the sources of hydrogen peroxide production by heart mitochondria?

(2010) Vera G. Grivennikova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Chaperone-mediated autophagy in protein quality control

(2010) Esperanza Arias et al.   CURRENT OPINION IN CELL BIOLOGY

Does calorie restriction induce mitochondrial biogenesis? A reevaluation

(2010) Chad R. Hancock et al.   FASEB JOURNAL

Parkin Mono-ubiquitinates Bcl-2 and Regulates Autophagy

(2010) Dong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

The regulation of autophagy - unanswered questions

(2010) Y. Chen et al.   JOURNAL OF CELL SCIENCE

Impact of long-term caloric restriction on cardiac senescence: Caloric restriction ameliorates cardiac diastolic dysfunction associated with aging

(2010) Ken Shinmura et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The emerging role of iron dyshomeostasis in the mitochondrial decay of aging

(2010) Jinze Xu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies

(2010) J. H. Lee et al.   SCIENCE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Cardiac Aging in Mice and Humans: The Role of Mitochondrial Oxidative Stress

(2010) Dao-Fu Dai et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

(2010) E Morselli et al.   Cell Death & Disease

A Microarray-Based Genetic Screen for Yeast Chronological Aging Factors

(2010) Mirela Matecic et al.   PLoS Genetics

The late stage of autophagy: cellular events and molecular regulation

(2010) Jingjing Tong et al.   Protein & Cell

Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging

(2009) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway

(2009) Narasimman Gurusamy et al.   CARDIOVASCULAR RESEARCH

Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

Heart Disease and Stroke Statistics—2009 Update

(2009) et al.   CIRCULATION

Suppression of Phosphoinositide 3-Kinase Prevents Cardiac Aging in Mice

(2009) Yasutaka Inuzuka et al.   CIRCULATION

Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging

(2009) Dao-Fu Dai et al.   CIRCULATION

Cellular Mechanisms of Cardioprotection by Calorie Restriction: State of the Science and Future Perspectives

(2009) Emanuele Marzetti et al.   CLINICS IN GERIATRIC MEDICINE

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Chronic ingestion of 2-deoxy-d-glucose induces cardiac vacuolization and increases mortality in rats

(2009) Robin K. Minor et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial oxidative stress and dysfunction in myocardial remodelling

(2008) H. Tsutsui et al.   CARDIOVASCULAR RESEARCH

The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death

(2008) Francesco Cecconi et al.   DEVELOPMENTAL CELL

Quality control of mitochondria: protection against neurodegeneration and ageing

(2008) Takashi Tatsuta et al.   EMBO JOURNAL

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart

(2008) J.L. Barger et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Recycle or die: The role of autophagy in cardioprotection

(2008) Åsa B. Gustafsson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY