Telomeres and Mitochondria in the Aging Heart

Effects of Age and Heart Failure on Human Cardiac Stem Cell Function

(2011) Daniela Cesselli et al.   AMERICAN JOURNAL OF PATHOLOGY

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

(2011) Michael Rera et al.   Cell Metabolism

PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy

(2011) Christian Riehle et al.   CIRCULATION RESEARCH

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

(2011) A. Safdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

(2010) Dao-Fu Dai et al.   AGING CELL

Association Between Left Ventricular Mass and Telomere Length in a Population Study

(2010) T. Kuznetsova et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia

(2010) Susanne A. Wolf et al.   BRAIN BEHAVIOR AND IMMUNITY

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion

(2010) Chiao-Po Hsu et al.   CIRCULATION

Heart Disease and Stroke Statistics—2011 Update

(2010) Véronique L. Roger et al.   CIRCULATION

PGC-1 Coactivators in Cardiac Development and Disease

(2010) Glenn C. Rowe et al.   CIRCULATION RESEARCH

TERRA biogenesis, turnover and implications for function

(2010) Sascha Feuerhahn et al.   FEBS LETTERS

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

(2010) Boyi Gan et al.   NATURE

The Power of Exercise: Buffering the Effect of Chronic Stress on Telomere Length

(2010) Eli Puterman et al.   PLoS One

Telomere length and outcome in heart failure

(2009) Pim van der Harst et al.   ANNALS OF MEDICINE

Leukocyte telomere length and coronary artery calcification

(2009) Arch G. Mainous et al.   ATHEROSCLEROSIS

Dyskeratosis congenita, stem cells and telomeres

(2009) Michael Kirwan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

(2009) Sihem Boudina et al.   CIRCULATION

Association of Leukocyte Telomere Length With Echocardiographic Left Ventricular Mass

(2009) Ramachandran S. Vasan et al.   CIRCULATION

Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging

(2009) Dao-Fu Dai et al.   CIRCULATION

Global Gene Expression Profiling in the Failing Myocardium

(2009) Masanori Asakura et al.   CIRCULATION JOURNAL

Control by Circulating Factors of Mitochondrial Function and Transcription Cascade in Heart Failure

(2009) Anne Garnier et al.   Circulation-Heart Failure

TERRA: telomeric repeat-containing RNA

(2009) Brian Luke et al.   EMBO JOURNAL

Cardiac mitochondrial function and tissue remodelling are improved by a non-antihypertensive dose of enalapril in spontaneously hypertensive rats

(2009) Barbara Piotrkowski et al.   FREE RADICAL RESEARCH

Disruption of the Ang II type 1 receptor promotes longevity in mice

(2009) Ariela Benigni et al.   JOURNAL OF CLINICAL INVESTIGATION

Telomere Diseases

(2009) Rodrigo T. Calado et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Turnover After the Fallout

(2009) Charles E. Murry et al.   SCIENCE

The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

(2008) John J. Lehman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

The Association Between Physical Activity in Leisure Time and Leukocyte Telomere Length

(2008) Lynn F. Cherkas   ARCHIVES OF INTERNAL MEDICINE

Prognostic Value of Leukocyte Telomere Length in Patients With Stable Coronary Artery Disease

(2008) Ramin Farzaneh-Far et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Age-related transcriptional changes in gene expression in different organs of mice support the metabolic stability theory of aging

(2008) Thore C. Brink et al.   BIOGERONTOLOGY

Blood leucocyte telomere DNA content predicts vascular telomere DNA content in humans with and without vascular disease

(2008) W. R. W. Wilson et al.   EUROPEAN HEART JOURNAL

Transcriptional coactivators PGC-1  and PGC-l  control overlapping programs required for perinatal maturation of the heart

(2008) L. Lai et al.   GENES & DEVELOPMENT

Expanding the clinical phenotype of autosomal dominant dyskeratosis congenita caused by TERT mutations

(2008) L. Basel-Vanagaite et al.   HAEMATOLOGICA

Mitochondrial centrality in heart failure

(2008) José Marín-García et al.   HEART FAILURE REVIEWS

PGC-1α and ERRα target gene downregulation is a signature of the failing human heart

(2008) Smita Sihag et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY