In the Thick of It

Short Communication: The Cardiac Myosin Binding Protein C Arg502Trp Mutation

(2010) Adam J. Saltzman et al.   CIRCULATION RESEARCH

Genetics of hypertrophic cardiomyopathy

(2010) Tetsuo Konno et al.   CURRENT OPINION IN CARDIOLOGY

Common Structural Motifs for the Regulation of Divergent Class II Myosins

(2010) Susan Lowey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Differences between the N-Terminal Domains of Mouse and Human Myosin Binding Protein-C

(2010) Justin F. Shaffer et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Malignant and benign mutations in familial cardiomyopathies: Insights into mutations linked to complex cardiovascular phenotypes

(2010) Qian Xu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Species-specific differences in the Pro-Ala rich region of cardiac myosin binding protein-C

(2010) Justin F. Shaffer et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development

(2010) Brett A. Colson et al.   JOURNAL OF PHYSIOLOGY-LONDON

The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathy

(2009) L. Carrier et al.   CARDIOVASCULAR RESEARCH

Cardiac Myosin Binding Protein-C Phosphorylation in a β-Myosin Heavy Chain Background

(2009) Sakthivel Sadayappan et al.   CIRCULATION

Cardiac Myosin-Binding Protein C Mutations and Hypertrophic Cardiomyopathy

(2009) Sabine J. van Dijk et al.   CIRCULATION

Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice

(2009) Nicolas Vignier et al.   CIRCULATION RESEARCH

Evidence From Human Myectomy Samples That MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy Through Haploinsufficiency

(2009) Steven Marston et al.   CIRCULATION RESEARCH

The Myosin-binding Protein C Motif Binds to F-actin in a Phosphorylation-sensitive Manner

(2009) Justin F. Shaffer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stressing the giant: A new approach to understanding dilated cardiomyopathy

(2009) Marion Lewis Greaser   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Phosphorylation and function of cardiac myosin binding protein-C in health and disease

(2009) David Barefield et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Single molecule kinetics in the familial hypertrophic cardiomyopathy D166V mutant mouse heart

(2009) Priya Muthu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Role of the N-Terminus of the Myosin Essential Light Chain in Cardiac Muscle Contraction

(2009) Katarzyna Kazmierczak et al.   JOURNAL OF MOLECULAR BIOLOGY

A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia

(2009) Perundurai S Dhandapany et al.   NATURE GENETICS

Acceleration of Crossbridge Kinetics by Protein Kinase A Phosphorylation of Cardiac Myosin Binding Protein C Modulates Cardiac Function

(2008) Carl W. Tong et al.   CIRCULATION RESEARCH

Protein Kinase A–Mediated Phosphorylation of cMyBP-C Increases Proximity of Myosin Heads to Actin in Resting Myocardium

(2008) Brett A. Colson et al.   CIRCULATION RESEARCH

Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice

(2008) W. Glenn L. Kerrick et al.   FASEB JOURNAL

Ablation of Ventricular Myosin Regulatory Light Chain Phosphorylation in Mice Causes Cardiac Dysfunctionin Situand Affects Neighboring Myofilament Protein Phosphorylation

(2008) Sarah B. Scruggs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of the Myosin Binding Protein C Motif to Functional Effects in Permeabilized Rat Trabeculae

(2008) Maria V. Razumova et al.   JOURNAL OF GENERAL PHYSIOLOGY

Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics

(2008) Michael J. Greenberg et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myosin Binding Protein C Positioned to Play a Key Role in Regulation of Muscle Contraction: Structure and Interactions of Domain C1

(2008) Abdessamad Ababou et al.   JOURNAL OF MOLECULAR BIOLOGY

Ubiquitin-Proteasome System Impairment Caused by a Missense Cardiac Myosin-binding Protein C Mutation and Associated with Cardiac Dysfunction in Hypertrophic Cardiomyopathy

(2008) Udin Bahrudin et al.   JOURNAL OF MOLECULAR BIOLOGY

Understanding the Organisation and Role of Myosin Binding Protein C in Normal Striated Muscle by Comparison with MyBP-C Knockout Cardiac Muscle

(2008) Pradeep K. Luther et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of the C1 domain of Cardiac Myosin Binding Protein-C: Implications for Hypertrophic Cardiomyopathy

(2008) Lata Govada et al.   JOURNAL OF MOLECULAR BIOLOGY

Myosin filament 3D structure in mammalian cardiac muscle

(2008) Hind A. AL-Khayat et al.   JOURNAL OF STRUCTURAL BIOLOGY

Three-dimensional structure of vertebrate cardiac muscle myosin filaments

(2008) M. E. Zoghbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypertrophic cardiomyopathy: the genetic determinants of clinical disease expression

(2008) Andre Keren et al.   Nature clinical practice. Cardiovascular medicine

Stability and Kinetic Properties of C5-Domain from Myosin Binding Protein C and its Mutants

(2007) Carlo Guardiani et al.   BIOPHYSICAL JOURNAL