Article
Medicine, General & Internal
Jurij M. Kalisnik, Giuseppe Santarpino, Andrea Balbierer, Janez Zibert, Ferdinand A. Vogt, Matthias Fittkau, Theodor Fischlein
Summary: This study aimed to evaluate the thromboembolic risk in patients with atrial fibrillation (AF) and aortic stenosis undergoing aortic valve replacement (AVR) with or without left atrial appendage (LAA) amputation. The results showed that patients who underwent LAA amputation had a lower incidence of ischemic stroke during the follow-up period, without increasing perioperative risk.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Andrei Churyla, Adin-Cristian Andrei, Jane Kruse, James L. Cox, Olga N. Kislitsina, Menghan Liu, S. Chris Malaisrie, Patrick M. McCarthy
Summary: Surgical ablation of atrial fibrillation during cardiac surgery is recommended, yet often overlooked. This study compared the outcomes of isolated surgical aortic valve replacement with and without atrial fibrillation ablation. The results showed that ablation for atrial fibrillation did not increase mortality or stroke risk within 30 days postoperatively, but was associated with a higher rate of pacemaker implantation.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Maciej Kubala, Yohann Bohbot, Dan Rusinaru, Sylvestre Marechaux, Momar Diouf, Christophe Tribouilloy
Summary: Atrial fibrillation (AF) is a strong predictor of mortality in patients with severe aortic stenosis (AS), even in asymptomatic or minimally symptomatic patients. Aortic valve replacement (AVR) is associated with lower mortality in AF patients, but among patients who undergo AVR, AF is associated with excess mortality. Further studies are needed to confirm the benefits of AVR in asymptomatic patients with AF and severe AS.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Hyung Ki Jeong, Namsik Yoon, Ju Han Kim, Nuri Lee, Dae Yong Hyun, Min Chul Kim, Ki Hong Lee, Yo Cheon Jeong, In Seok Jeong, Hyun Ju Yoon, Kye Hun Kim, Hyung Wook Park, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho
Summary: AF after AVR is associated with worse outcomes, especially in the SAVR group. TAVR may be a favorable treatment option for high-risk patients with AF.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Raheel Ahmed, Hiroyuki Sawatari, Saurabh Deshpande, Hassan Khan, Providencia Rui, Mohammed Y. Khanji, Akil A. Sherif, Keerthi Jaliparthy, Sathish Reddy, Vuyisile T. Nkomo, Cholenahally N. Manjunath, Cha Yong-Mei, Virend K. Somers, Peter A. Brady, Anwar A. Chahal, Deepak Padmanabhan
Summary: Atrial fibrillation (AF) is common in patients undergoing aortic valve replacement and significantly increases length of stay and healthcare costs, but does not independently increase in-hospital mortality in patients undergoing surgical or transcatheter aortic valve replacement.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Bahira Shahim, S. Chris Malaisrie, Isaac George, Vinod H. Thourani, Angelo B. Biviano, Mark Russo, David L. Brown, Vasilis Babaliaros, Robert A. Guyton, Susheel K. Kodali, Tamim M. Nazif, Samir Kapadia, Philippe Pibarot, James M. McCabe, Mathew Williams, Philippe Genereux, Michael Lu, Xiao Yu, Maria Alu, John G. Webb, Michael J. Mack, Martin B. Leon, Ioanna Kosmidou
Summary: The study aimed to assess the occurrence and impact of early and late postoperative atrial fibrillation or flutter in patients with severe aortic stenosis undergoing transcatheter or surgical aortic valve replacement. Late postoperative atrial fibrillation or flutter was significantly associated with worse outcomes, while early postoperative atrial fibrillation or flutter was not an independent predictor.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Adham K. Alkurashi, Sorin V. Pislaru, Jeremy J. Thaden, Jeremy D. Collins, Thomas A. Foley, Kevin L. Greason, Mackram F. Eleid, Gurpreet S. Sandhu, Mohamad A. Alkhouli, Samuel J. Asirvatham, Yong-Mei Cha, Eric E. Williamson, Juan A. Crestanello, Patricia A. Pellikka, Jae K. Oh, Vuyisile T. Nkomo
Summary: Patients with atrial fibrillation (AF) may have underestimated aortic stenosis (AS) severity at the time of referral for transcatheter aortic valve replacement (TAVR). This study compared flow-independent computed tomographic aortic valve calcium scores (AVCS) to mean gradient (MG) in AF versus sinus rhythm (SR) in patients undergoing TAVR. The results showed that AVCS were higher than expected by MG in AF, particularly in men with high-gradient AS (HGAS). This suggests late diagnosis of severe AS in men with AF and HGAS. Further studies are needed to examine the extent of AS severity underestimation by echocardiography in AF.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2022)
Article
Cardiac & Cardiovascular Systems
Ahmed Ammar, Ahmed I. Elbatran, Nadeev Wijesuriya, Bunny Saberwal, Syed Y. Ahsan
Summary: Atrial fibrillation is common among patients with severe aortic stenosis, and new onset AF is frequently seen after TAVR. AF has a significant impact on outcomes in TAVR patients, but there is a lack of clear evidence about the optimal management.
TRENDS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Sandeep Banga, George S. Abela, Frank Saltiel, Tim Fischell, Jagadeesh K. Kalavakunta, Abhinav Sood, George Jolly, Khalid Najib, Haya Al-Ali, Mohammed Qintar, Jason Bazil, Yashbir Singh, Vishal Gupta
Summary: Atrial fibrillation (AF) is a common complication in patients who underwent transcatheter aortic valve implantation, and some of these patients have preexisting AF. The management of these patients is complex, especially after the procedure when there is a sudden change in hemodynamics. Currently, there are no established guidelines for managing AF in patients who underwent transcatheter aortic valve replacement. This review article discusses the use of medications for rate and rhythm control strategies, as well as the role of newer oral anticoagulation medications and left atrial occlusion devices in stroke prevention after the procedure. It also highlights new advances in preventing AF occurrence after transcatheter aortic valve implantation.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Jung-Hwan Kim, Joon-Young Song, Hyo-Sup Shim, Sak Lee, Young-Nam Youn, Hyun-Chel Joo, Kyung-Jong Yoo, Seung-Hyun Lee
Summary: Cardiac adipose tissue is associated with the recurrence of atrial fibrillation, but its correlation with maze surgery is unclear. This study found a positive correlation between the adipose component of the left atrium and AF recurrence in patients who underwent a modified Cox maze III procedure. Therefore, it may be necessary to use statins in a randomized study to reduce perioperative adipose tissue.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Rikhard Bjorn, Maunu Nissinen, Joonas Lehto, Markus Malmberg, Fredrik Yannopoulos, K. E. Juhani Airaksinen, Juha E. K. Hartikainen, Tuomo Nieminen, Fausto Biancari, Jarmo Gunn, Tuomas O. Kiviniemi
Summary: New-onset atrial fibrillation (NOAF) during surgical aortic valve replacement is associated with an increased risk of atrial fibrillation recurrence and all-cause mortality.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Review
Cardiac & Cardiovascular Systems
Tammy Ryan, Alexander Grindal, Rehman Jinah, Kevin J. Um, Maria E. Vadakken, Avinash Pandey, Iqbal H. Jaffer, Jeff S. Healey, Emilie P. Belley-Cote, William F. McIntyre
Summary: The aim of this study was to investigate the occurrence, outcomes, and predictors of new-onset atrial fibrillation (NOAF) after transcatheter aortic valve replacement (TAVR). The results showed that NOAF after TAVR was associated with longer hospitalization, increased risk of stroke within 30 days, higher 30-day mortality, major or life-threatening bleeding, and permanent pacemaker implantation. Risk factors for developing NOAF after TAVR included higher Society of Thoracic Surgeons score, transapical access, pulmonary hypertension, chronic kidney disease, peripheral vascular disease, and severe mitral regurgitation.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Satoshi Kainuma, Masataka Mitsuno, Koichi Toda, Shigeru Miyagawa, Yasushi Yoshikawa, Hiroki Hata, Daisuke Yoshioka, Takuji Kawamura, Ai Kawamura, Noriyuki Kashiyama, Takayoshi Ueno, Toru Kuratani, Haruhiko Kondoh, Toshihiro Funatsu, Arudo Hiraoka, Taichi Sakaguchi, Hidenori Yoshitaka, Yukitoshi Shirakawa, Toshiki Takahashi, Masayuki Sakaki, Takafumi Masai, Shunsuke Saito, Osamu Monta, Tetsuhisa Kitamura, Sho Komukai, Atsushi Hirayama, Kazuhiro Taniguchi, Yuji Miyamoto, Yoshiki Sawa
Summary: In patients undergoing nonmitral valve surgery, a concurrent Cox-Maze procedure showed better AF- and event-free survival compared to PVI, without an increased risk of early mortality. The Cox-Maze group had higher rates for 5-year survival and freedom from composite events. Adjusted results still showed a lower risk of overall mortality and composite adverse events for the Cox-Maze procedure.
ANNALS OF THORACIC SURGERY
(2021)
Article
Engineering, Biomedical
Kenichi Sasaki, Takashi Kunihara, Shinya Suzuki, Goro Matsumiya, Hirotsugu Fukuda, Norihiko Shiiya, Tadaaki Koyama, Tatsuhiko Komiya, Hitoshi Yaku, Akira Shiose, Akihiko Usui, Junjiro Kobayashi, Yosuke Ishii, Masahiro Tanji, Hiroyasu Misumi, Toshiya Ohtsuka, Naoki Yoshimura, Yuji Hiramatsu, Takashi Nitta
Summary: This study compared the effectiveness of surgical ablation for atrial fibrillation during aortic valve replacement. The results showed that both maze and pulmonary vein isolation could restore sinus rhythm at 2 years and resulted in favorable early and midterm survival rates.
Article
Cardiac & Cardiovascular Systems
Jawad H. Butt, Ole De Backer, Jonas B. Olesen, Thomas A. Gerds, Eva Havers-Borgersen, Gunnar H. Gislason, Christian Torp-Pedersen, Lars Sondergaard, Lars Kober, Emil L. Fosbol
Summary: This study found that in AF patients undergoing TAVI, treatment with DOACs compared to VKAs did not significantly increase the risk of arterial thromboembolism, bleeding, or all-cause mortality.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2021)
Article
Health Care Sciences & Services
Yoonsuh Jung, Hong Zhang, Jianhua Hu
STATISTICAL METHODS IN MEDICAL RESEARCH
(2019)
Article
Medicine, General & Internal
Go-Woon Kim, Younsuck Koh, Chae-Man Lim, Jin Won Huh, Sung Ho Jung, Joon Bum Kim, Sang-Bum Hong
KOREAN JOURNAL OF INTERNAL MEDICINE
(2018)
Article
Statistics & Probability
Yoonsuh Jung
JOURNAL OF APPLIED STATISTICS
(2019)
Review
Statistics & Probability
Yoonsuh Jung, Jianhua Hu
JOURNAL OF THE KOREAN STATISTICAL SOCIETY
(2019)
Article
Statistics & Probability
Yoonsuh Jung
COMMUNICATIONS IN STATISTICS-THEORY AND METHODS
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Seung Hyuk Nam, Hyuck Kim, Sun Kyun Ro
ANNALS OF THORACIC SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Hyo Jun Jang, Jun Ho Lee, Seung Hyuk Nam, Sun Kyun Ro
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2020)
Article
Statistics & Probability
Yoonsuh Jung, Steven N. MacEachern, Hang Kim
Summary: This study proposes a modified check loss function with quadratic adjustment to guard against overfitting, which has been empirically proven through various simulation settings of linear and nonlinear regressions.
JOURNAL OF APPLIED STATISTICS
(2021)
Article
Cardiac & Cardiovascular Systems
Jun Ho Lee, Hyun Ju Lee, Hyun-Kyung Park, Ja-Hye Ahn, Hee Sun Kim, Hyo Jun Jang, Sun Kyun Ro, Hyuck Kim
JOURNAL OF CARDIOTHORACIC SURGERY
(2020)
Article
Statistics & Probability
Wooyoung Shin, Mingang Kim, Yoonsuh Jung
Summary: In this study, a modified check loss function is suggested to improve the efficiency of model selection in quantile regression. The proposed adjustment to generalized cross-validation is designed to reflect the target quantile and sample size, aiming to increase efficiency. Real data sets and simulation studies are used to evaluate the performance of the proposed methods in linear and nonlinear quantile regression models.
JOURNAL OF THE KOREAN STATISTICAL SOCIETY
(2022)
Article
Computer Science, Artificial Intelligence
Yoonsuh Jung, Hayoung Kim
Summary: This paper introduces a method for improving model selection by measuring heteroscedasticity using IQR and reducing its impact through weighted prediction error. The proposed method reduces the impact of large prediction errors via weighted prediction, leading to better model and parameter selection. The benefits of this method are demonstrated in simulations and with two real data sets.
STATISTICAL ANALYSIS AND DATA MINING
(2022)
Article
Cardiac & Cardiovascular Systems
Jun Ho Lee, Yongil Cho, Yun Jin Kim, Yang Hyun Cho, Yong Ho Jeong, Hyo Jun Jang, Sun Kyun Ro, Hyuck Kim
Summary: Individuals with a lower income level have an increased risk of poorer long-term outcomes after coronary artery bypass grafting (CABG) compared to those with a higher income level. This study provides evidence of the impact of individual socioeconomic status on clinical outcomes after CABG.
ANNALS OF THORACIC SURGERY
(2022)
Article
Medicine, General & Internal
Jeong-Hun Shin, Sun Kyun Ro
Summary: This article reports a case of newly developed coronary artery aneurysm in an adult with recent COVID-19 infection. The authors call for further evaluation of the impact of COVID-19 on the occurrence of coronary artery aneurysm.
Review
Cardiac & Cardiovascular Systems
Sun Kyun Ro, Kei Sato, Shinichi Ijuin, Declan Sela, Gabriele Fior, Silver Heinsar, Ji Young Kim, Jonathan Chan, Hideaki Nonaka, Aaron C. W. Lin, Gianluigi Li Bassi, David G. Platts, Nchafatso G. Obonyo, Jacky Y. Suen, John F. Fraser
Summary: The right ventricle (RV) plays a critical role in hemodynamics and failure of the right ventricle often leads to poor clinical outcomes. Current diagnosis of right ventricular failure relies on patients' symptoms and signs, but not on objective parameters. The geometric complexity of the RV makes it difficult to accurately assess its function. Advanced techniques, such as artificial intelligence and 3-dimensional assessment, have the potential to improve RV assessment by increasing accuracy and reproducibility. Further studies are needed to validate these advanced technologies in different populations.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Jun Ho Lee, Yongil Cho, Yang Hyun Cho, Hyunggoo Kang, Tae Ho Lim, Hyo Jun Jang, Sun Kyun Ro, Hyuck Kim
JOURNAL OF KOREAN MEDICAL SCIENCE
(2020)