Article
Clinical Neurology
Matthew P. Light, Kimberly Y. Kreitinger, Euyhyun Lee, Pamela N. DeYoung, Avni Lakhani, Brent Siegel, Lori B. Daniels, Atul Malhotra, Robert L. Owens
Summary: Sleep apnea severity and a central apnea pattern may be associated with myocardial injury. Respiratory polygraphy with serial biomarker assessment is feasible in this population, and combining this approach with interventions (e.g., positive airway pressure) may help establish if a link exists between sleep apnea and subclinical myocardial injury.
SLEEP AND BREATHING
(2023)
Article
Clinical Neurology
Leonie Kolb, Michael Arzt, Stefan Stadler, Katharina Heider, Lars S. Maier, Maximilian Malfertheiner
Summary: Early ASV usage predicts late ASV usage. In addition, low slow wave sleep before ASV initiation and subjective benefit from ASV may contribute to higher late ASV usage.
SLEEP AND BREATHING
(2021)
Article
Nutrition & Dietetics
Abidan Abulimiti, Ryo Naito, Takatoshi Kasai, Sayaki Ishiwata, Miho Nishitani-Yokoyama, Akihiro Sato, Shoko Suda, Hiroki Matsumoto, Jun Shitara, Shoichiro Yatsu, Azusa Murata, Megumi Shimizu, Takao Kato, Masaru Hiki, Hiroyuki Daida, Tohru Minamino
Summary: Malnutrition often occurs together with heart failure, leading to negative consequences. Cheyne-Stokes respiration (CSR) is commonly found in heart failure patients. However, the impact of CSR and malnutrition on the long-term prognosis of patients with acute decompensated heart failure (ADHF) is still unclear.
Review
Critical Care Medicine
Salam Zeineddine, James A. Rowley, Susmita Chowdhuri
Summary: Sleep-disordered breathing (SDB) has significant cardiovascular and neurological effects, with supplemental oxygen therapy showing mixed results in improving oxygen saturation and apnea severity compared to positive airway pressure therapy. Further research is needed to clarify the optimal dose and duration of nocturnal supplemental oxygen (NSO) and its combination with PAP in improving cardiovascular, sleep, and cognitive outcomes in SDB patients.
Review
Medicine, General & Internal
Ana Carolina Pereira Nunes Pinto, Aline Rocha, Luciano F. Drager, Geraldo Lorenzi-Filho, Daniela Pachito
Summary: The study aimed to evaluate the effectiveness and safety of non-invasive positive pressure ventilation (NIPV) for the treatment of adults with central sleep apnoea (CSA). The results showed that CPAP plus best supportive care may reduce central AHI in people with CSA associated with chronic heart failure compared to best supportive care alone. Further high-quality trials focusing on patient-centered outcomes are needed to determine the best treatment for different groups of CSA patients.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)
Article
Cardiac & Cardiovascular Systems
Alberto Giannoni, Chiara Borrelli, Gianluca Mirizzi, George B. Richerson, Michele Emdin, Claudio Passino
Summary: The study demonstrates that buspirone can decrease CO2 chemosensitivity in patients with heart failure, improving central apnoeas and oxygen saturation.
EUROPEAN JOURNAL OF HEART FAILURE
(2021)
Article
Clinical Neurology
Mahssa Karimi, Jan Hedner, Ludger Grote
Summary: Adaptive Servo Ventilation (ASV) treatment improves sleep quality, neurocognition, and daytime performance in patients with chronic heart failure (CHF) and Cheyne-Stokes respiration (CSR).
Article
Respiratory System
Renaud Tamisier, Jean-Louis Pepin, Holger Woehrle, Muriel Salvat, Gilles Barone-Rochette, Cecile Rocca, Eik Vettorazzi, Helmut Teschler, Martin Cowie, Patrick Levy
Summary: This study investigated the effect of ASV on sympathetic tone in patients with HFrEF and CSA. The results showed that ASV did not effectively suppress sympathetic activation in heart failure patients and was associated with increased cardiovascular mortality.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Satomi Imanari, Yasuhiro Tomita, Satoshi Kasagi, Fusae Kawana, Yuka Kimura, Sugao Ishiwata, Koji Narui, Takatoshi Kasai
Summary: The study found a modest correlation between AHI determined by the ASV device AutoSet CS (ASC) and that calculated by polysomnography (PSG) in patients with HF and SDB. However, the ASC device tended to overestimate AHI and showed moderate agreement with PSG results.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Clinical Neurology
Muhammad Yasir, Amina Pervaiz, Abdulghani Sankari
Summary: Obstructive sleep apnea is associated with cardiovascular risks, but previous studies have underestimated its prevalence. Using more physiological data can improve diagnosis sensitivity, and high-risk individuals should be identified for focused treatment.
FRONTIERS IN NEUROLOGY
(2022)
Review
Biochemistry & Molecular Biology
Michael Wester, Michael Arzt, Frederick Sinha, Lars Siegfried Maier, Simon Lebek
Summary: Heart failure with preserved ejection fraction (HFpEF) is a widespread disease with high morbidity and mortality, and sleep-disordered breathing (SDB) has been found to be closely associated with the development and progression of the obese HFpEF phenotype. Individualized therapeutic strategies and novel technologies like single-cell transcriptomics or CRISPR-Cas9 gene editing are needed to improve treatment outcomes.
Article
Medicine, General & Internal
Muhammed Gercek, Mustafa Gercek, Kanjo Alzein, Vanessa Sciacca, Christian Sohns, Philipp Sommer, Volker Rudolph, Henrik Fox
Summary: This study investigates the impact of sleep-disordered breathing (SDB) treatment on ventricular tachycardia (VT) burden in heart failure (HF) patients. The results show that SDB treatment leads to significant improvements in VT burden, antitachycardia pacing (ATP), and shock therapy in HF patients with implantable cardioverter-defibrillator (ICD). SDB treatment may also affect the survival of HF patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Ali Vazir, Chris J. Kapelios
Summary: Sleep-disordered breathing (SDB) is common in individuals with established cardiovascular disease (CVD), particularly heart failure (HF). SDB includes central sleep apnoea (CSA) and obstructive sleep apnoea (OSA), and investigating for SDB is recommended in certain patient groups. Continuous positive airway pressure (CPAP) can reduce the risk of adverse cardiovascular events in patients with CVD and OSA, but its effect on mortality is unclear. CPAP use may also be beneficial in patients with AF and OSA, but more evidence is needed for the treatment of HF and OSA.
Article
Cardiac & Cardiovascular Systems
Tao Wang, Fu-Chao Yu, Qin Wei, Xuan Xu, Liang Xie, Ning Ding, Jia-Yi Tong
Summary: This study explored the prevalence of sleep-disordered breathing (SDB) in patients with heart failure (HF) of different etiologies. The study found that SDB is common in HF patients and the prevalence and types of SDB varied in HF with different etiologies, which may be related to the different severities of HF.
CLINICAL CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Aline Rocha, Ana Carolina Pereira Nunes Pinto, Daniela Pachito, Luciano F. Drager, Geraldo Lorenzi-Filho, Alvaro N. Atallah
Summary: Central sleep apnoea (CSA) is a condition characterized by impaired breathing during sleep, and pharmacological treatment has shown some benefit in improving the symptoms and quality of life in patients with CSA. However, the available evidence is uncertain and further research is needed to establish the effectiveness and safety of pharmacological agents for CSA.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2023)