Review
Medicine, General & Internal
Carlos Escobar, Domingo Pascual-Figal, Luis Manzano, Julio Nunez, Miguel Camafort
Summary: Based on recent evidence, SGLT2 inhibitors, specifically dapagliflozin, are recommended as first-line therapy for managing heart failure patients, irrespective of ejection fraction, to reduce the burden of heart failure. Studies have shown that dapagliflozin significantly reduces the risk of cardiovascular death, all-cause death, total heart failure hospitalizations, and MACE in the entire spectrum of heart failure, with sustained benefits over time. Full implementation of dapagliflozin in clinical practice leads to a substantial reduction in hospitalizations for heart failure and death in real-life populations.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Vishal N. Rao, Robert J. Mentz, Amanda C. Coniglio, Michelle D. Kelsey, Marat Fudim, Gregg C. Fonarow, Roland A. Matsouaka, Adam D. DeVore, Melissa C. Caughey
Summary: Neighborhood socioeconomic status is associated with in-hospital heart failure outcomes. Patients from disadvantaged neighborhoods have a higher in-hospital mortality rate and are younger, more often Black or Hispanic, and have higher comorbidity burden.
CIRCULATION-HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Ambarish Pandey, Matthew W. Segar, Sumitabh Singh, Gordon Reeves, Christopher O'Connor, Ileana Pina, David Whellan, William Kraus, Robert Mentz, Dalane Kitzman
Summary: This study investigates the impact of baseline frailty on the efficacy of aerobic exercise training in patients with heart failure. The results show that aerobic exercise training significantly reduces the risk of all-cause hospitalization in frail patients, but the effect is not significant for non-frail patients.
Reprint
Nursing
Qiuge Zhao, Cancan Chen, Jie Zhang, Yi Ye, Xiuzhen Fan
Summary: This study conducted a systematic review to evaluate the effects of self-management interventions on heart failure knowledge, quality of life, and heart failure-related hospitalizations in patients with heart failure, revealing significant improvements in these areas. More high quality randomized controlled trials are needed to further explore the optimal self-management interventions for heart failure patients.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2021)
Article
Cardiac & Cardiovascular Systems
Yumiko Kawakubo Ichihara, Yasuyuki Shiraishi, Shun Kohsaka, Shintaro Nakano, Yuji Nagatomo, Tomohiko Ono, Makoto Takei, Munehisa Sakamoto, Atsushi Mizuno, Mitsunobu Kitamura, Nozomi Niimi, Takashi Kohno, Tsutomu Yoshikawa
Summary: This study found that patients with behavioral precipitant factors (PFs) had a higher risk of heart failure rehospitalization, despite having a lower risk of in-hospital death.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Li Shen, Pardeep Singh Jhund, Kieran Francis Docherty, Muthiah Vaduganathan, Mark Colquhoun Petrie, Akshay Suvas Desai, Lars Kober, Morten Schou, Milton Packer, Scott David Solomon, Xingwei Zhang, John Joseph Valentine McMurray
Summary: Previous guidelines for treating heart failure with reduced ejection fraction recommended initiating therapy in a chronological order based on trial history. However, this study suggests that accelerating treatment titration and optimizing treatment ordering may improve patient outcomes.
EUROPEAN HEART JOURNAL
(2022)
Article
Nutrition & Dietetics
Shirley Sze, Pierpaolo Pellicori, Jufen Zhang, Joan Weston, Andrew L. Clark
Summary: This prospective cohort study aimed to compare the short-term prognostic value of 9 commonly used malnutrition tools in patients with chronic heart failure. The study found that most tools were independently associated with worse morbidity and mortality in patients with CHF, with serum albumin providing comparable prognostic information to simple or multidimensional malnutrition tools.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Cardiac & Cardiovascular Systems
Vanessa Blumer, Robert J. Mentz, Jie-Lena Sun, Javed Butler, Marco Metra, Adriaan A. Voors, Adrian F. Hernandez, Christopher M. O'Connor, Stephen J. Greene
Summary: The study found that prior hospitalization for heart failure was not associated with 180-day mortality after accounting for patient characteristics measured during the index patient visit. Clinical confounders measured at the point-of-care may explain previously observed associations.
CIRCULATION-HEART FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Ersilia M. DeFilippis, John Henderson, Kelly M. Axsom, Maria Rosa Costanzo, Philip B. Adamson, Alan B. Miller, Marie-Elena Brett, Michael M. Givertz
Summary: The study found that after one year, heart failure patients could reduce pulmonary artery pressure and hospitalization frequency through cardiovascular monitoring, and gender did not affect the treatment effect. This study shows that ambulatory hemodynamic monitoring provides similar benefits for male and female heart failure patients.
CIRCULATION-HEART FAILURE
(2021)
Review
Cardiac & Cardiovascular Systems
Haijiang Xia, Hongfeng Shen, Wei Cha, Qiaoli Lu
Summary: This study provides evidence of the high risk of mortality and hospitalization outcomes in patients with heart failure and anemia through a meta-analysis. The findings confirm that anemia is an important and independent risk factor delineating the prognostic outcome of chronic heart failure, as suggested by previously published meta-analyses.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Nutrition & Dietetics
Nubia Rafaella Soares Moreira Torres, Fernanda Lambert de Andrade Freire, Raquel Costa Silva Dantas-Komatsu, Eduardo Paixao da Silva, Salomao Israel Monteiro Lourenco Queiroz, Niethia Regina Dantas de Lira, Rosiane Viana Zuza Diniz, Severina Carla Vieira Cunha Lima, Lucia Fatima Campos Pedrosa, Marcia Marilia Gomes Dantas Lopes, Karine Cavalcanti Mauricio Sena-Evangelista
Summary: This study aimed to assess the prevalence of inadequate micronutrient intake and its association with prognosis in patients with heart failure. The results showed a high prevalence of inadequate micronutrient intake in heart failure outpatients, but it was not associated with hospitalization and mortality.
Article
Nutrition & Dietetics
Yoshikuni Obata, Naoya Kakutani, Shintaro Kinugawa, Arata Fukushima, Takashi Yokota, Shingo Takada, Taisuke Ono, Takeshi Sota, Yoshiharu Kinugasa, Masashige Takahashi, Hisashi Matsuo, Ryuichi Matsukawa, Ichiro Yoshida, Isao Yokota, Kazuhiro Yamamoto, Miyuki Tsuchihashi-Makaya
Summary: Inadequate calorie intake is associated with worse clinical outcomes in stable outpatients with chronic HF, including higher risks of all-cause death and HF-related hospitalization. Further studies with direct measurements of dietary calorie intake and total energy expenditure are needed to clarify this relationship.
Review
Cardiac & Cardiovascular Systems
Teemu E. I. Drews, Jari Laukkanen, Tuomo Nieminen
Summary: This systematic review and meta-analysis found that non-invasive home telemonitoring did not significantly reduce all-cause hospitalizations and mortality in patients with recently decompensated heart failure. However, interventions that directly altered heart failure medication showed significant effects on reducing all-cause hospitalizations.
Article
Cardiac & Cardiovascular Systems
Joyce N. Njoroge, John R. Teerlink
Summary: ADHF is a leading admission diagnosis worldwide, with incompletely understood pathophysiology and limited therapeutic options. Patients often experience high in-hospital morbidity and mortality due to suboptimal medical management leading to persistent congestion upon hospital discharge and inadequate initiation of life-saving therapies before discharge. There has been no new therapy approved for ADHF in decades, highlighting the need for expanding available therapies for these high-risk patients.
CIRCULATION RESEARCH
(2021)
Article
Medicine, General & Internal
Charles Faselis, Phillip H. Lam, Samir Patel, Cherinne Arundel, Gerasimos Filippatos, Prakash Deedwania, Michael R. Zile, Samuel Wopperer, Tran Nguyen, Richard M. Allman, Gregg C. Fonarow, Ali Ahmed
Summary: This study found that the prescription of loop diuretics for heart failure patients upon discharge can impact long-term clinical outcomes, with the effects being modified by the level of congestion upon admission. Patients with no congestion, mild-to-moderate congestion, and severe congestion experienced different outcomes.
AMERICAN JOURNAL OF MEDICINE
(2021)