Article
Cardiac & Cardiovascular Systems
Jonathan M. Kalman, Ahmed M. Al-Kaisey, Ramanathan Parameswaran, Joshua Hawson, Robert D. Anderson, Michael Lim, David Chieng, Stephen A. Joseph, Alex McLellan, Joseph B. Morton, Paul B. Sparks, Geoffrey Lee, Prashanthan Sanders, Peter M. Kistler
Summary: This study aimed to determine if the timing of catheter ablation for atrial fibrillation (AF) affects arrhythmia outcomes. The results showed that there was no significant difference in the atrial arrhythmia free survival at 12 months post-ablation between patients who underwent early ablation and those who underwent delayed ablation. Other secondary outcomes also showed no significant difference. Therefore, delaying AF ablation by 12 months for antiarrhythmic drug management does not reduce the efficacy of ablation.
EUROPEAN HEART JOURNAL
(2023)
Article
Cell Biology
Keisuke Okawa, Satoshi Taya, Takeshi Morimoto, Ryu Tsushima, Yuya Sudo, Ai Sakamoto, Eisuke Saito, Masahiro Sogo, Masatomo Ozaki, Masahiko Takahashi
Summary: This study aimed to investigate the impact of AF ablation on the incidence of cardiovascular events and death in very old nonvalvular AF patients. The results showed that in nonvalvular AF patients aged 80 years and older, those who underwent AF ablation had a significantly lower incidence of cardiovascular events and death compared to those who received medical therapy only.
Review
Cardiac & Cardiovascular Systems
Gianluigi Bisleri, Arjun K. Pandey, Subodh Verma, Syed M. Ali Hassan, Bobby Yanagawa, Masud Khandaker, Mario Gaudino, Andrea M. Russo, Atul Verma, Deepak L. Bhatt, Andrew C. T. Ha
Summary: Hybrid ablation is a novel therapy that combines minimally invasive surgical and percutaneous catheter-based techniques for the management of atrial fibrillation (AF). Observational studies have shown approximately 70% success rates but higher risks compared to catheter-based ablation. Hybrid ablation is typically offered to patients with persistent or longstanding persistent AF, requiring two procedures. While a randomized trial demonstrated its superiority over catheter-based ablation, it also showed higher complication rates. Contemporary studies have shown a decrease in the incidence of serious complications. Additional randomized trials are needed to determine the risks, benefits, and cost effectiveness of hybrid ablation in clinical practice.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Geoffroy Ditac, Pierre Jean Cottinet, Minh Quyen Le, Daniel Grinberg, Josselin Duchateau, Kevin Gardey, Arnaud Dulac, Antoine Deliniere, Christelle Haddad, Julie Boussuge-Roze, Frederic Sacher, Pierre Jais, Philippe Chevalier, Francis Bessiere
Summary: Atrial fibrillation (AF) catheter ablation procedure contributes significantly to GHG emissions, with a carbon footprint of 76.9 kg CO2-e. With approximately 600,000 annual procedures worldwide, AF catheter ablation leads to 125 tons of CO2 emissions every day, equivalent to a daily car ride of 700,000 km. Electrophysiology catheters and patches are identified as the main contributors to the carbon footprint, highlighting the importance of reducing, reusing, and recycling these items.
Article
Cardiac & Cardiovascular Systems
Karim Benali, Paul Khairy, Nefissa Hammache, Adrian Petzl, Antoine Da Costa, Atul Verma, Jason G. Andrade, Laurent Macle
Summary: A systematic review and pooled analysis of randomized control trials showed that catheter ablation of atrial fibrillation is associated with low rates of procedure-related complications and mortality, which have declined over the past decade.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Elena Arbelo, Nikolaos Dagres
Summary: This article critically reviews the recommendations of the 2020 ESC guidelines for the management of AF in light of two landmark trials, emphasizing the safety of contemporary rhythm control treatment and the importance of personalized treatment strategies.
Article
Physiology
Jae-Hyuk Lee, Oh-Seok Kwon, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
Summary: Catheter ablation is an effective method for treating atrial fibrillation, but it may lead to atrial tissue damage and increase the risk of stiff LA physiology. Factors such as diabetes, E/Em ratio, LA pulse pressure, low LA voltage, empirical extra-PV ablation, and radiofrequency ablation duration are associated with stiff LA physiology after AFCA.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Ramanathan Parameswaran, Ahmed M. Al-Kaisey, Jonathan M. Kalman
Summary: Catheter ablation is a key strategy for managing atrial fibrillation, with technological advancements focusing on improving safety and effectiveness. Guidelines recommend the procedure for symptomatic patients with paroxysmal or persistent AF, but evidence from trials is mixed. Pulmonary vein isolation remains a cornerstone technique in AF ablation, with ongoing developments in technology aimed at enhancing patient outcomes.
NATURE REVIEWS CARDIOLOGY
(2021)
Review
Immunology
Dishiwen Liu, Yajia Li, Qingyan Zhao
Summary: Atrial fibrillation (AF) is a serious healthcare burden with high morbidity and complications. Catheter ablation, although curable, currently has a low long-term success rate. Inflammation and fibrosis play significant roles in AF progression, and the artificial inflammatory response caused by catheter ablation may impact long-term prognosis. This review focuses on the different types of inflammatory cell death induced by various ablation techniques, as well as the structural and electrical remodeling caused by inflammation and its association with AF recurrence after catheter ablation. Pulsed-field ablation shows promise as a revolutionary innovation with faster, safer, better tissue selectivity, and less inflammatory response.
JOURNAL OF INFLAMMATION RESEARCH
(2023)
Review
Cardiac & Cardiovascular Systems
Richard G. Trohman, Henry D. Huang, Parikshit S. Sharma
Summary: Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with significant cardiac morbidity and mortality. As the population ages, the burden of AF is projected to increase by more than 60% by 2050. Although progress has been made in the treatment and management of AF, prevention and reduction of thromboembolic complications remain a work in progress.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Lu Zhou, Liu He, Wei Wang, Changyi Li, Songnan Li, Ribo Tang, Caihua Sang, Nian Liu, Chenxi Jiang, Ronghui Yu, Deyong Long, Xin Du, Jianzeng Dong, Changsheng Ma
Summary: This study aimed to compare the effect of catheter ablation and drug therapy on recurrent AT/AF patients after AF catheter ablation. The results showed that repeat catheter ablation may significantly reduce the risk of composite cardiovascular mortality, ischemic stroke, and major bleeding events compared to medical therapy in patients with recurrent AT/AF after a catheter ablation procedure. However, there were no statistically significant differences between the two groups in terms of secondary endpoints.
Review
Cardiac & Cardiovascular Systems
Zhi-Jie Mao, Yan Pei, Hui Lin, Yin Xiang, Zhou-Qing Huang, Fang-Yi Xiao, Yi-He Chen
Summary: High-power radiofrequency catheter ablation shows superior efficacy in maintaining sinus rhythm for patients with atrial fibrillation, while also reducing procedure and fluoroscopy times. Additionally, there is no significant difference in the risk of complications between high-power and conventional-power ablation techniques.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Signe Westh Christensen, Selina Kikkenborg Berg, Naja Hulvej Rod, Ann-Dorthe Olsen Zwisler, Lau Caspar Thygesen, Signe Stelling Risom
Summary: A moderate-high level of physical activity was found to be associated with a lower risk of serious adverse events in patients undergoing AF and/or AFL ablation, compared to those with low physical activity levels.
Review
Medicine, General & Internal
Francesco Maria Angelo Brasca, Roberto Mene, Giovanni Battista Perego
Summary: Atrial fibrillation (AF) is a common arrhythmia, especially in patients with structural heart disease (SHD). Catheter ablation (CA) has emerged as an effective strategy for rhythm control in AF patients and has potential benefits beyond symptom relief. This review summarizes the current knowledge of CA in SHD patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Luigi Di Biase, Juan Carlos Diaz, Xiao-Dong Zhang, Jorge Romero
Summary: Pulsed field ablation is a novel energy source for the treatment of atrial fibrillation, with advantages in both safety and effectiveness compared to other energy sources, allowing targeted treatment and minimizing damage.
TRENDS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Junji Yamaguchi, Yoshihide Takahashi, Tasuku Yamamoto, Miki Amemiya, Masahiro Sekigawa, Yasuhiro Shirai, Susumu Tao, Tatsuya Hayashi, Atsuhiko Yagishita, Masateru Takigawa, Masahiko Goya, Tetsuo Sasano
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Mihoko Kawabata, Masahiko Goya, Shingo Maeda, Atsuhiko Yagishita, Yoshihide Takahashi, Tetsuo Sasano, Kenzo Hirao
INTERNATIONAL HEART JOURNAL
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Atsuhiko Yagishita, Masahiko Goya, Susumu Sakama, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Article
Multidisciplinary Sciences
Misaki Hasegawa, Tomoyoshi Komiyama, Kengo Ayabe, Susumu Sakama, Tetsuri Sakai, Kyong Hee Lee, Masahiro Morise, Atsuhiko Yagishita, Mari Amino, Ayumi Sasaki, Eiichiro Nagata, Hiroyuki Kobayashi, Koichiro Yoshioka, Yuji Ikari
Summary: By conducting various tests on VT-NMS patients, the study found significant differences in blood pressure and adenylate cyclase activity during the head-up tilt test. Additionally, it was observed that during the tilt test, VT-NMS patients had higher blood pressure, pulse rate, and adenylate cyclase activity compared to healthy volunteers.
Article
Multidisciplinary Sciences
Tetsuri Sakai, Atsuhiko Yagishita, Masahiro Morise, Susumu Sakama, Takeshi Ijichi, Kengo Ayabe, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Summary: This study aimed to investigate the impact of improved peak exercise oxygen consumption (V?O-2) after cardiac rehabilitation (CR) on the incidence of arrhythmias in patients with heart failure. The findings suggest that improvement in peak V?O-2 is associated with lower mortality and incidence of atrial arrhythmias in HF patients.
SCIENTIFIC REPORTS
(2021)
Article
Biology
Kengo Ayabe, Tomoyoshi Komiyama, Misaki Hasegawa, Tetsuri Sakai, Masahiro Morise, Susumu Sakama, Atsuhiko Yagishita, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Summary: Syncope, commonly encountered in clinical practice, can be neurally mediated, cardiac, or orthostatic. A negative head-up tilt test result may help anticipate unexpected clinical events within a few years.
Article
Medicine, General & Internal
Shingo Maeda, Masahiko Goya, Yasuhiro Shirai, Atsuhiko Yagishita, Susumu Tao, Jackson Jeikai Liang, Ruben Casado Arroyo, Yoshihide Takahashi, Mihoko Kawabata, Tetsuo Sasano, Kenzo Hirao
Summary: This study aimed to identify novel predictors of effective atrial anti-tachycardia pacing (A-ATP) for terminating atrial fibrillation (AF) in patients undergoing catheter ablation. The results showed that simultaneous biatrial A-ATP from the right atrium (RA) and coronary sinus (CS) could terminate AF in patients with paroxysmal AF. The predictors for successful termination included longer AF cycle length and higher AF stability.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Susumu Sakama, Atsuhiko Yagishita, Tetsuri Sakai, Masahiro Morise, Kengo Ayabe, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Summary: This study demonstrates that AI-guided CTI ablation in combination with CU is feasible and effective in reducing radiation exposure in patients with typical atrial flutter.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Mari Amino, Masatoshi Yamazaki, Koichiro Yoshioka, Noboru Kawabe, Sachie Tanaka, Takashi Shimokawa, Ryoko Niwa, Naoki Tomii, Shigeto Kabuki, Etsuo Kunieda, Atsuhiko Yagishita, Yuji Ikari, Itsuo Kodama
Summary: This study investigated the effects of carbon ion beam on gap junction expression and sympathetic innervation. It was found that heavy ion radiation reduced vulnerability to atrial tachycardia/fibrillation and ventricular tachycardia/fibrillation in hypercholesterolemic elderly rabbits and improved cardiac conductivity. The results suggest involvement of connexin-40/43 upregulation and suppression of sympathetic nerve sprouting as underlying mechanisms.
CIRCULATION JOURNAL
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Atsuhiko Yagishita, Kengo Ayabe, Susumu Sakama, Mari Amino, Yuji Ikari, Koichiro Yoshioka
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Atsuhiko Yagishita, Susumu Sakama, Kengo Ayabe, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Summary: A novel mapping algorithm called CoherentTM has been developed to help identify the mechanism of atrial tachycardia (AT) by utilizing vectors and global patterns of propagation. This study compared the diagnostic accuracy of coherent mapping with that of ripple mapping and found that coherent mapping had a higher diagnostic accuracy for typical macroreentrant ATs compared to other ATs. However, the termination rate of ATs was high in the first lesion set guided by ripple mapping.
IJC HEART & VASCULATURE
(2023)
Article
Cardiac & Cardiovascular Systems
Atsuhiko Yagishita, Yasuteru Yamauchi, Yuichiro Sagawa, Kyong Hee Lee, Susumu Sakama, Kengo Ayabe, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Summary: This study aimed to determine the utility of open-window mapping (OWM) in visualizing the location and width of accessory pathways (APs) in patients with Wolff-Parkinson-White syndrome. The results showed that OWM successfully visualized the location and width of APs, and it could be used to predict whether multiple radio frequency applications are required for broad APs.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Correction
Cardiac & Cardiovascular Systems
Atsuhiko Yagishita, Masahiko Goya, Susumu Sakama, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Article
Cardiac & Cardiovascular Systems
Kyong Hee Lee, Atsuhiko Yagishita, Yohei Ohno, Tetsuri Sakai, Katsuaki Sakai, Junichi Miyamoto, Hitomi Horinouchi, Susumu Sakama, Norihiko Kamioka, Tsutomu Murakami, Kengo Ayabe, Mari Amino, Koichiro Yoshioka, Yuji Ikari
Summary: Late-onset atrioventricular block (AVB) occurred in a minority of patients undergoing transcatheter aortic valve replacement (TAVR). Greater vigilance, particularly in patients with transient conduction disturbances during the periprocedural period following self-expanding valve implantation, is warranted.
Article
Cardiac & Cardiovascular Systems
Atsuhiko Yagishita, Masahiko Goya, Yoshito Iesaka, Junichi Nitta, Atsushi Takahashi, Yasutoshi Nagata, Hitoshi Hachiya, Osamu Inaba, Yukihiro Inamura, Yasuaki Tanaka, Keita Watanabe, Susumu Tao, Yasuhiro Shirai, Tasuku Yamamoto, Shinya Shiohira, Kikou Akiyoshi, Masahiro Sekigawa, Shingo Maeda, Takeshi Sasaki, Yoshihide Takahashi, Mihoko Kawabata, Kenzo Hirao
JOURNAL OF ARRHYTHMIA
(2020)