Article
Cardiac & Cardiovascular Systems
Raghav Sharma, Aditya Vikram Ruia, Tek Singh Mahant
Summary: Coronary artery aneurysms after drug eluting stents are rare, and this study presents a case series of type II coronary aneurysms after implantation of Everolimus eluting stents. The slight increase in incidence in Everolimus stents does not reach statistical significance, and there was better outcomes with surgical repair for patients with giant aneurysms compared to covered stent deployment. Further research is needed to confirm these findings.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Ae-Young Her, Eun-Seok Shin, Sunwon Kim, Bitna Kim, Tae-Hyun Kim, Chang-Bae Sohn, Byung Joo Choi, Yongwhi Park, Jung Rae Cho, Young-Hoon Jeong
Summary: This study investigated the clinical impact of drug-coated balloon (DCB) treatment in patients with diabetes mellitus (DM) and multivessel coronary artery disease (CAD), and found that DCB treatment reduced the risk of major adverse cardiovascular events (MACE) in patients with DM, but not in those without DM.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hongfei Xi, Jiasi Liu, Tao Xu, Zhe Li, Xuanting Mou, Yu Jin, Shudong Xia
Summary: This study analyzed the risk factors for in-stent restenosis (ISR) after the first implantation of drug-eluting stents (DES) in patients with coronary heart disease (CHD) and developed a nomogram model to predict the risk of ISR. The study identified hypertension, HbA1c, mean stent diameter, total stent length, thyroxine, and fibrinogen as important predictors for ISR. The nomogram prediction model can effectively identify high-risk individuals and provide practical decision-making information for follow-up interventions.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, Research & Experimental
Matej Strycek, Lukas Jaworski, Rostislav Polasek, Pavol Tomasov
Summary: Coronary artery perforation is a rare but potentially fatal complication of percutaneous coronary intervention. We report a case of massive main vessel coronary perforation in a patient with acute ST segment elevation myocardial infarction, which was successfully treated with a second drug-eluting stent. This unusual therapeutic approach was used to maintain blood flow to the large side branch.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Daniele Giacoppo, Hector A. Alvarez-Covarrubias, Tobias Koch, Salvatore Cassese, Erion Xhepa, Thorsten Kessler, Jens Wiebe, Michael Joner, Willibald Hochholzer, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Sebastian Kufner
Summary: This study aims to compare the interventional strategies for the treatment of drug-eluting stent (DES) in-stent restenosis (ISR). The comparative efficacy and safety of plain balloon (PB), paclitaxel-coated balloon (PCB), and paclitaxel-eluting stent (PES) for percutaneous coronary intervention (PCI) of DES-ISR were evaluated for a 10-year follow-up. The results showed no significant difference among the treatments in clinical follow-up and primary endpoints, but PES and PCB were significantly superior to PB in target lesion revascularization.
EUROPEAN HEART JOURNAL
(2023)
Article
Pharmacology & Pharmacy
Mangesh Sane, Vikas Dighe, Rucha Patil, Puthusserickal A. Hassan, Santosh Gawali, Vandana Patravale
Summary: Localized drug delivery with sustained elution characteristics from nanocarrier coated stents is a viable therapeutic approach to address concerns related to coronary stent therapy. A Sirolimus and Bivalirudin releasing nanoparticles (NPs) coated stent was fabricated for concurrent mitigation of vascular restenosis and acute stent thrombosis, showing superior anti-proliferative activity and higher cellular uptake in human coronary artery smooth muscle cells.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Pharmacology & Pharmacy
Hak-Il Lee, Won-Kyu Rhim, Eun-Young Kang, Bogyu Choi, Jun-Hyeok Kim, Dong-Keun Han
Summary: The study proposed a multilayer-coated balloon catheter to enhance drug transfer efficiency, effectively load drugs, and reduce drug loss during treatment. Experimental results show that this method can be effectively applied to coronary intervention.
Review
Public, Environmental & Occupational Health
Kui Li, Kaijun Cui, Xuechuan Dan, Jian Feng, Xiaobo Pu
Summary: This meta-analysis suggests that drug-coated balloon (DCB) has better short-term therapeutic efficacy and safety than drug-eluting stent (DES) for treating small-vessel coronary artery lesions in diabetic patients.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Soichiro Enomoto, Shoichi Kuramitsu, Tomohiro Shinozaki, Masanobu Ohya, Hiromasa Otake, Futoshi Yamanaka, Hiroki Shiomi, Masahiro Natsuaki, Gaku Nakazawa, Kenji Ando, Kazushige Kadota, Shigeru Saito, Toshihiro Tamura, Takeshi Kimura
Summary: This study assessed over 600 patients with DES implantation-related ST, finding no significant difference in the incidence of definite RST between first-generation and second-generation DES. Early ST and multivessel ST were identified as independent risk factors for definite RST. Definite RST significantly increased mortality risk for patients with DES thrombosis.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Medicine, General & Internal
Juan Zhang, Qian Zhang, Ke Zhao, Yu-Jing Bian, Yang Liu, Yi-Tao Xue
Summary: This study used logistic regression analysis to explore the risk factors for in-stent restenosis (ISR) after stent implantation in patients with coronary heart disease (CHD). The results showed that a family history of CHD, history of type 2 diabetes, hypertension, smoking, and drinking, discontinuation of aspirin, use of conventional dose statins, calcified lesions, >= 3 implanted stents, stent length >= 30 mm, stent diameter < 3 mm, and tandem stenting were all risk factors for ISR within 2 years after PCI in patients with CHD.
Article
Cardiac & Cardiovascular Systems
Takahiro Jimba, Masayasu Ikutomi, Atsuko Tsukamoto, Masashiro Matsushita, Masao Yamasaki
Summary: This study investigated the impact of hinge motion on stent edge-related restenosis (SER) in the right coronary artery (RCA) after implantation of current-generation drug-eluting stents (DES). The results indicated that hinge angle and residual plaque burden were independent predictors of SER, with a synergistic effect observed when excessive hinge motion and residual plaque burden coexisted. These findings suggest that mechanical stress at stent edges and its interaction with residual plaque may contribute to SER progression.
CIRCULATION JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Kun Wang, Le Wang, Hongliang Cong, Jingxia Zhang, Yuecheng Hu, Yingyi Zhang, Rui Zhang, Wenyu Li, Wei Qi
Summary: The best revascularization strategy for patients with mild to moderate ischaemic heart failure (ejection fraction [EF] 35-50%) remains uncertain. This study found that coronary artery bypass grafting (CABG) may be superior to drug-eluting stent (DES) implantation in terms of long-term survival rate and rate of repeat coronary revascularization for these patients.
Review
Cardiac & Cardiovascular Systems
Yang Chen, Dandan Li, Yanhui Liao, Xiongda Yao, Yuehua Ruan, Kai Zou, Hanhui Liao, Jingwen Ding, Hao Qin, Zuozhong Yu, Yuanbin Zhao, Longlong Hu, Renqiang Yang
Summary: The incidence of coronary stent fracture (CSF) has been increasing in recent years, with a significant rise over the past 20 years. The duration of stent placement after stent implantation does not affect the incidence of CSF, but the type of drug-eluting stents (DES) and lesions in the right coronary artery (RCA) have an influence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Hematology
Hiroshi Sugita, Masayuki Motohiro, Syun Morishita, Masami Tanaka, Satoshi Tsujimoto, Ichiro Shiojima
Summary: The study investigated the incidence of in-stent restenosis (ISR) and its predictors in chronic hemodialysis patients after drug-eluting stent (DES) implantation. It was found that a small minimal lumen diameter (MLD), longer lesion length (LL), and the use of rotational atherectomy were independent predictors of ISR. Additionally, there was no significant difference in ISR rates between first- and second-generation DESs.
BLOOD PURIFICATION
(2022)
Article
Cardiac & Cardiovascular Systems
Ming Yi, Wen-hui Tang, Shuai Xu, Xiao Ke, Qiang Liu
Summary: This study aimed to explore risk factors for in-stent restenosis (ISR) in elderly patients with coronary heart disease and type 2 diabetes after the first drug-eluting stent (DES) implantation. The study found that fasting blood glucose level during the perioperative period and long-term variation of HbA1c during follow-up were related to the incidence and degree of stenosis of ISR.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Ji Hyun Kim, Sung Eun Kim, Yu Kyung Cho, Chul-Hyun Lim, Moo In Park, Jin Won Hwang, Jae-Sik Jang, Minkyung Oh
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2018)
Correction
Gastroenterology & Hepatology
Ji Hyun Kim, Sung Eun Kim, Yu Kyung Cho, Chul-Hyun Lim, Moo In Park, Jin Won Hwang, Jae-Sik Jang, Minkyung Oh
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2018)
Meeting Abstract
Cardiac & Cardiovascular Systems
Jae-Sik Jang, Tae-Hyun Yang, Dae-Kyeong Kim, Dong-Soo Kim, Eun-Ji Park, Yeong-Ju Jeong
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Article
Medicine, General & Internal
Hack-Lyoung Kim, Jae-Sik Jang, Myung-A Kim, Jae-Bin Seo, Woo-Young Chung, Sang-Hyun Kim, Seung-Jung Park, Tae-Jin Youn, Myeong-Ho Yoon, Jae-Hwan Lee, Kiyuk Chang, Myung Ho Jeong, Rak Kyeong Choi, Myeong-Ki Hong, Hyo-Soo Kim
Article
Cardiac & Cardiovascular Systems
Duk-Woo Park, Osung Kwon, Jae-Sik Jang, Sung-Cheol Yun, Hanbit Park, Do-Yoon Kang, Jung-Min Ahn, Pil Hyung Lee, Seung-Whan Lee, Seong-Wook Park, Si Wan Choi, Sang-Gon Lee, Hyuck-Jun Yoon, Taehoon Ahn, Moo Hyun Kim, Deuk Young Nah, Sung Yun Lee, Jei Keon Chae, Seung-Jung Park
Meeting Abstract
Cardiac & Cardiovascular Systems
Jin-Ho Kim, Chang-Wook Nam, Bum-Kee Hong, June-Hong Kim, Doo Soo Jeon, Jang Whan Bae, Sang-Hyun Kim, Keon-Woong Moon, Byung-Ryul Cho, Doo Il Kim, Jae-Sik Jang
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Yeong-Min Lee, Soon-Hee Lee, Tae-Hee Kim, Eun-Ji Park, Young-Ah Park, Jae-Sik Jang
Summary: This study found that both GLP-1 agonists and SGLT-2 inhibitors have comparable cardiovascular outcomes in patients with type 2 diabetes. However, SGLT-2 inhibitors are associated with a more pronounced reduction in hospitalization for heart failure and a lower risk of treatment discontinuation compared to GLP-1 agonists.
CARDIOLOGY JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Uram Jin, Kyoung-Woo Seo, Hyoung-Mo Yang, Hong-Seok Lim, Byoung-Joo Choi, So-Yeon Choi, Joon-Han Shin, Seung-Jea Tahk, Sang-Yong Yoo, Seung Woon Rha, Woo-Young Chung, Chi-Hoon Kim, Ki-Bum Won, Wook Bum Pyun, Jae Sik Jang, Sung Yun Lee, Young Joon Hong, Moo Hyun Kim, Soon Jun Hong, Yun-Seok Choi, Hee-Yeol Kim, Rak Kyeong Choi, Woong Chol Kang, Eun Joo Cho, Myeong-Ho Yoon
Summary: This study compared the efficacy and safety of 3-month versus 6-month dual-antiplatelet therapy (DAPT) in patients implanted with Coroflex ISAR polymer-free drug-eluting stents (DESs). The results showed that there was no significant difference in the occurrence of cardiovascular death, myocardial infarction, target vessel revascularization, and bleeding between the two treatment durations.
JOURNAL OF INVASIVE CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Byong-Kyu Kim, Deuk-Young Nah, Kang Un Choi, Jun-Ho Bae, Moo-Yong Rhee, Jae-Sik Jang, Keon-Woong Moon, Jun-Hee Lee, Hee-Yeol Kim, Seung-Ho Kang, Woo Hyuk Song, Seung Uk Lee, Byung-Ju Shim, Hangjae Chung, Min Su Hyon
KOREAN CIRCULATION JOURNAL
(2020)
Meeting Abstract
Cardiac & Cardiovascular Systems
Yeong-Min Lee, Young-Ah Park, Han-Young Jin, Jeong-Sook Seo, Jae-sik Jang, Dae-Kyeong Kim, Dong-Soo Kim, Tae-Hyun Yang
Meeting Abstract
Cardiac & Cardiovascular Systems
Yeong-Min Lee, Eun-Ji Park, Young-Ah Park, Jeong-Sook Seo, Han-Young Jin, Tae-Hyun Yang, Dae-Kyung Kim, Dong-Soo Kim, Jae-Sik Jang
Article
Cardiac & Cardiovascular Systems
Dong-Ho Shin, Hyun-Jae Kang, Jae-Sik Jang, Keon-Woong Moon, Young Bin Song, Duk-Woo Park, Jang-Whan Bae, Juhan Kim, Seung-Ho Hur, Byung Ok Kim, Dong Woon Jeon, Donghoon Choi, Kyoo-Rok Han
KOREAN CIRCULATION JOURNAL
(2019)
Article
Cardiac & Cardiovascular Systems
Jin-Ho Kim, Woonggil Choi, Ki-Chang Kim, Chang-Wook Nam, Bum-Kee Hong, June-Hong Kim, Doo Soo Jeon, Jang-Whan Bae, Sang-Hyun Kim, Keon-Woong Moon, Byung-Ryul Cho, Doo Il Kim, Jae-Sik Jang
KOREAN CIRCULATION JOURNAL
(2019)
Meeting Abstract
Cardiac & Cardiovascular Systems
Jae-Sik Jang, Young-Ah Park, Han-Young Jin, Jeong-Sook Seo, Tae-Hyun Yang, Dae-Kyeong Kim, Dong-Soo Kim, Yong-Rak Cho
Article
Endocrinology & Metabolism
Bo Hyun Kim, Jae Sik Jang, Yong Seop Kwon, June Hyung Kim, In Joo Kim, Chang Won Lee
ENDOCRINOLOGY AND METABOLISM
(2018)