Article
Cardiac & Cardiovascular Systems
Satomi Imanari, Yasuhiro Tomita, Satoshi Kasagi, Fusae Kawana, Yuka Kimura, Sugao Ishiwata, Koji Narui, Takatoshi Kasai
Summary: The study found a modest correlation between AHI determined by the ASV device AutoSet CS (ASC) and that calculated by polysomnography (PSG) in patients with HF and SDB. However, the ASC device tended to overestimate AHI and showed moderate agreement with PSG results.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Critical Care Medicine
Salam Zeineddine, James A. Rowley, Susmita Chowdhuri
Summary: Sleep-disordered breathing (SDB) has significant cardiovascular and neurological effects, with supplemental oxygen therapy showing mixed results in improving oxygen saturation and apnea severity compared to positive airway pressure therapy. Further research is needed to clarify the optimal dose and duration of nocturnal supplemental oxygen (NSO) and its combination with PAP in improving cardiovascular, sleep, and cognitive outcomes in SDB patients.
Article
Clinical Neurology
Leonie Kolb, Michael Arzt, Stefan Stadler, Katharina Heider, Lars S. Maier, Maximilian Malfertheiner
Summary: Early ASV usage predicts late ASV usage. In addition, low slow wave sleep before ASV initiation and subjective benefit from ASV may contribute to higher late ASV usage.
SLEEP AND BREATHING
(2021)
Review
Cardiac & Cardiovascular Systems
Ye-Chen Han, Zhu-Jun Shen, Shu-Yang Zhang, Peng Gao, Ruo-Lan Xiang, Hao Qian, Hong-Zhi Xie
Summary: This study aimed to explore the effects of noninvasive positive-pressure ventilation on cardiac function and survival in patients with sleep-disordered breathing and chronic congestive heart failure. Short-term treatment with adaptive servo-ventilation was significantly beneficial for event-free survival in patients with reduced ejection fraction and central sleep apnea, but had no effect on all-cause mortality. Periodic short-term positive-pressure ventilation can significantly improve cardiac function, which is beneficial for the survival of such patients.
HEART FAILURE REVIEWS
(2021)
Review
Clinical Neurology
Muhammad Yasir, Amina Pervaiz, Abdulghani Sankari
Summary: Obstructive sleep apnea is associated with cardiovascular risks, but previous studies have underestimated its prevalence. Using more physiological data can improve diagnosis sensitivity, and high-risk individuals should be identified for focused treatment.
FRONTIERS IN NEUROLOGY
(2022)
Review
Biochemistry & Molecular Biology
Michael Wester, Michael Arzt, Frederick Sinha, Lars Siegfried Maier, Simon Lebek
Summary: Heart failure with preserved ejection fraction (HFpEF) is a widespread disease with high morbidity and mortality, and sleep-disordered breathing (SDB) has been found to be closely associated with the development and progression of the obese HFpEF phenotype. Individualized therapeutic strategies and novel technologies like single-cell transcriptomics or CRISPR-Cas9 gene editing are needed to improve treatment outcomes.
Article
Medicine, General & Internal
Muhammed Gercek, Mustafa Gercek, Kanjo Alzein, Vanessa Sciacca, Christian Sohns, Philipp Sommer, Volker Rudolph, Henrik Fox
Summary: This study investigates the impact of sleep-disordered breathing (SDB) treatment on ventricular tachycardia (VT) burden in heart failure (HF) patients. The results show that SDB treatment leads to significant improvements in VT burden, antitachycardia pacing (ATP), and shock therapy in HF patients with implantable cardioverter-defibrillator (ICD). SDB treatment may also affect the survival of HF patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Ali Vazir, Chris J. Kapelios
Summary: Sleep-disordered breathing (SDB) is common in individuals with established cardiovascular disease (CVD), particularly heart failure (HF). SDB includes central sleep apnoea (CSA) and obstructive sleep apnoea (OSA), and investigating for SDB is recommended in certain patient groups. Continuous positive airway pressure (CPAP) can reduce the risk of adverse cardiovascular events in patients with CVD and OSA, but its effect on mortality is unclear. CPAP use may also be beneficial in patients with AF and OSA, but more evidence is needed for the treatment of HF and OSA.
Review
Cardiac & Cardiovascular Systems
Jingting Wang, Naima Covassin, Tianxin Dai, Zhengyang Fan, Patiguli Yisilamu, Dance Sun, Fei Li, Jiang Xie
Summary: The effectiveness of ASV therapy in reducing cardiovascular and all-cause mortality in CSA patients remains debatable. However, ASV treatment can significantly reduce the risk of MACEs in patients with nadir nocturnal saturation <= 80%. For heart failure patients, those with LVEF > 33% or NYHA I/II classification benefit from ASV therapy in lowering MACEs risk compared to usual care.
Article
Cardiac & Cardiovascular Systems
Christoph Fisser, Lara Gall, Jannis Bureck, Victoria Vaas, Joerg Priefert, Sabine Fredersdorf, Florian Zeman, Dominik Linz, Holger Woehrle, Renaud Tamisier, Helmut Teschler, Martin R. R. Cowie, Michael Arzt
Summary: This study aimed to evaluate the effects of ASV on nocturnal ventricular arrhythmias in patients with CSA and HFrEF. The results showed that adding ASV to guideline-based medical management did not significantly affect nocturnal ventricular ectopy or tachyarrhythmia over a period of 12 months.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Clinical Neurology
Alberto A. Zambon, Federica Trucco, Aidan Laverty, Mollie Riley, Deborah Ridout, Adnan Y. Manzur, Francois Abel, Francesco Muntoni
Summary: This study aimed to investigate the prevalence and features of sleep disordered breathing (SDB) in pediatric patients with Duchenne muscular dystrophy (DMD) and explore the relationship between lung function and sleep abnormalities. The results showed a correlation between forced vital capacity (FVC) and the presence of nocturnal hypoventilation (NH). Additionally, some patients exhibited NH despite having FVC > 50%. These findings have important implications for the clinical management of SDB.
Article
Cardiac & Cardiovascular Systems
Tao Wang, Fu-Chao Yu, Qin Wei, Xuan Xu, Liang Xie, Ning Ding, Jia-Yi Tong
Summary: This study explored the prevalence of sleep-disordered breathing (SDB) in patients with heart failure (HF) of different etiologies. The study found that SDB is common in HF patients and the prevalence and types of SDB varied in HF with different etiologies, which may be related to the different severities of HF.
CLINICAL CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Michael Arzt, Olaf Oldenburg, Andrea Graml, Jurgen Schnepf, Erland Erdmann, Helmut Teschler, Christoph Schoebel, Holger Woehrle
Summary: The prevalence of sleep-disordered breathing (SDB) in heart failure with preserved ejection fraction (HFpEF) is high, but lower than in patients with mildly reduced (HFmrEF) or reduced (HFrEF) ejection fraction. Male patients with HFpEF are more likely to have moderate-to-severe SDB compared to female patients. In both sexes, the proportion of obstructive sleep apnea (OSA) in SDB patients with HFpEF is higher than in those with HFrEF.
Article
Cardiac & Cardiovascular Systems
Sergio Caravita, Andrea Faini, Carlo Vignati, Sara Pelucchi, Elisabetta Salvioni, Gaia Cattadori, Claudia Baratto, Camilla Torlasco, Mauro Contini, Alessandra Villani, Gabriella Malfatto, Elisa Perger, Carolina Lombardi, Alberto Piperno, Piergiuseppe Agostoni, Gianfranco Parati
Summary: Intravenous ferric carboxymaltose can improve symptoms in patients with heart failure, anemia, and iron deficiency by improving chemoreflex sensitivity and sleep-related breathing disorders.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Sayaki Ishiwata, Takatoshi Kasai, Akihiro Sato, Shoko Suda, Hiroki Matsumoto, Jun Shitara, Shoichiro Yatsu, Azusa Murata, Megumi Shimizu, Takao Kato, Masaru Hiki, Yuya Matsue, Ryo Naito, Hiroyuki Daida, Tohru Minamino
Summary: Untreated SDB in hospitalized AHF patients was associated with worse clinical outcomes, which could be improved by PAP treatment. However, the potential benefits may be reduced in less compliant patients.
CLINICAL RESEARCH IN CARDIOLOGY
(2022)