Article
Public, Environmental & Occupational Health
Russell Luepker, Niki C. Oldenburg, Jeffrey R. Misialek, Jeremy R. Van't Hof, John R. Finnegan, Milton Eder, Sue Duval
Summary: The study revealed that aspirin use for primary cardiovascular disease prevention is common, but some individuals are either overusing or underusing it. Discussion with a physician may lead to some improvement in appropriate use but is also associated with overuse and underuse.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Blerim Mujaj, Zhen-Yu Zhang, Wen-Yi Yang, Lutgarde Thijs, Fang-Fei Wei, Peter Verhamme, Christian Delles, Javed Butler, Peter Sever, Roberto Latini, John G. F. Cleland, Faiez Zannad, Jan A. Staessen
Summary: This study found that aspirin use was associated with incident HF in patients at risk, independent of other risk factors. In the absence of conclusive trial evidence, caution should be exercised in prescribing aspirin to patients at risk of HF or with HF.
Article
Medicine, General & Internal
Jong Hun Kim, Dougho Park, Hyun Sun Lim, Min Jin Kang, Jun Hong Lee, Seo Yeon Yoon, Hyoung Seop Kim
Summary: This study evaluated the effects of aspirin in primary prevention and examined disability grades and mortality after ischemic/hemorrhagic stroke and myocardial infarction. The results showed that the risk of severe neurological disability was higher in the aspirin group for hemorrhagic stroke, and the aspirin group had higher 90-day and long-term mortality risks compared to the control group.
Review
Endocrinology & Metabolism
Hua Ma, Qing Gu, Huining Niu, Xiaohua Li, Rong Wang
Summary: In adults with diabetes, aspirin for primary prevention of cardiovascular disease and all-cause mortality events showed significantly lower major adverse cardiovascular events (MACE) compared to the control group, but no significant difference was found in terms of all-cause mortality, cardiovascular mortality, or bleeding events.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Pharmacology & Pharmacy
E. Demirci, O. Celik, C. Cil, V. O. Tanik, K. Memic Sancar, O. Orscelik, M. M. Resulzade, C. Kaya, T. Kiris, V Dogan, O. Basaran
Summary: This study investigated the appropriateness of aspirin use in diabetic patients according to recent guidelines. The study found that inappropriate aspirin use was common among diabetic patients, and there were notable differences in the indications for aspirin use according to different guidelines.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Multidisciplinary Sciences
Neily Zakiyah, Robin Tuytten, Philip N. Baker, Louise C. Kenny, Maarten J. Postma, Antoinette D. van Asselt
Summary: This study developed a new screening test for preeclampsia and assessed its cost-effectiveness from a healthcare payer perspective. The results showed that the new test was more effective and less costly in the UK, while higher thresholds were needed for it to be considered cost-effective in the Netherlands, Ireland, and Sweden.
Article
Cardiac & Cardiovascular Systems
Mei-Chuan Lee, Chia-Te Liao, Han Siong Toh, Chih-Chen Chou, Wei-Ting Chang, Zhih-Cherng Chen, Wen-Shiann Wu, Tsung Yu, Carol Strong
Summary: This study found that low-dose rivaroxaban plus aspirin is less likely to be a cost-effective alternative to aspirin for patients with stable cardiovascular diseases in Taiwan. However, there may be pharmacoeconomic incentives for this regimen among patients with chronic coronary artery diseases. The pharmacoeconomic incentives are influenced by factors such as drug price, event treatment fees, and willingness-to-pay threshold.
CARDIOVASCULAR DRUGS AND THERAPY
(2021)
Article
Obstetrics & Gynecology
Emily S. Lau
Summary: The use of aspirin for primary prevention of cardiovascular disease is debated. Low-dose aspirin may be considered for women aged 40 to 59 years with a 10-year cardiovascular risk of 10% or more and no increased bleeding risk. Low-dose aspirin for primary prevention is not advised for low-risk women or women aged 60 years or older.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2023)
Article
Multidisciplinary Sciences
Muhammad Irfan, Michael P. Cameron, Gazi Hassan
Summary: Approximately three billion people globally rely on solid fuels for cooking and heating, causing indoor air pollution, especially in developing countries. Research shows that adopting LPG, natural gas, and electric stoves can effectively reduce indoor air pollution.
Article
Public, Environmental & Occupational Health
Amirparviz Jamshidi, Rajabali Daroudi, Eline Aas, Davood Khalili
Summary: The IraPEN program, developed in Iran based on the WHO package of essential noncommunicable disease interventions, was found to be highly cost-effective in preventing cardiovascular diseases. The intervention yielded positive health outcomes and cost savings for both individuals with and without diabetes. Overall, the program showed great potential in improving the health of Iranian individuals.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Environmental Sciences
Geoffrey H. Donovan, Jeffrey P. Prestemon, Demetrios Gatziolis, Yvonne L. Michael, Abigail R. Kaminski, Payam Dadvand
Summary: Several recent longitudinal studies have shown that exposure to natural environment is linked to lower non-accidental mortality. This study used a natural experiment to examine the impact of 30 years of tree planting on various causes of mortality in Portland, Oregon. The results revealed that each tree planted was associated with significant reductions in non-accidental and cardiovascular mortality, and the association between tree planting and non-accidental mortality increased as trees aged and grew.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Pharmacology & Pharmacy
Yu Chen, Fuli Chen, Jie Liao, Hukui Han, Gang Li, Long Zhou
Summary: This study aims to investigate the relationship between low- or high-dose preventive aspirin use and the risk of death among US adults. The results showed that low-dose aspirin use did not decrease the risk of death from any causes, while high-dose aspirin use increased the risk of cardiovascular disease death.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Medicine, Research & Experimental
Emanuela Ricciotti, Garret A. FitzGerald
Summary: Aspirin is a milestone treatment for the secondary prevention of cardiovascular disease, but its role in primary prevention is still debated. While it may have some protective effects against colorectal cancer, further studies are needed to confirm its benefits for primary prevention of cardiovascular disease and cancer in apparently healthy individuals.
ANNUAL REVIEW OF MEDICINE, VOL 72, 2021
(2021)
Article
Medicine, General & Internal
Nanfang Li, Wen Wen, Xintian Cai, Qing Zhu, Junli Hu, Mulalibieke Heizhati, Yujuan Yuan, Lin Gan, Yujie Dang, Wenbo Yang, Jing Hong, Xiangyang Zhang
Summary: Continuous aspirin use increases the incidence of cardiovascular adverse events in hypertensive patients with obstructive sleep apnea receiving aspirin for primary prevention of cardiovascular disease.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Pharmacology & Pharmacy
Binghao Zhao, Qian Wu, Li Wang, Chen Liao, Yifei Dong, Jingsong Xu, Yiping Wei, Wenxiong Zhang
Summary: Aspirin intake reduces the risk of cardiovascular events but increases the risk of bleeding in primary prevention of cardiovascular disease. It is essential to conduct clear examinations or assessments to determine an individual's cardiovascular disease risk before prescribing aspirin, promoting personalized treatment.
FRONTIERS IN PHARMACOLOGY
(2021)
