Green Tea Epigallocatechin-3-Gallate Suppresses Autoimmune Arthritis Through Indoleamine-2,3-Dioxygenase Expressing Dendritic Cells and the Nuclear Factor, Erythroid 2-Like 2 Antioxidant Pathway

The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells

(2015) Alexandra E. Turley et al.   CYTOKINE

Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges

(2015) Josef S. Smolen et al.   Nature Reviews Rheumatology

Safety of Nonsteroidal Antiinflammatory Drugs in Patients with Cardiovascular Disease

(2015) Ilya M. Danelich et al.   PHARMACOTHERAPY

Safety of synthetic and biological DMARDs: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis

(2014) Sofia Ramiro et al.   ANNALS OF THE RHEUMATIC DISEASES

Methotrexate in combination with other DMARDs is not superior to methotrexate alone for remission induction with moderate-to-high-dose glucocorticoid bridging in early rheumatoid arthritis after 16 weeks of treatment: the CareRA trial

(2014) P Verschueren et al.   ANNALS OF THE RHEUMATIC DISEASES

Analysis of the effect of the active compound of green tea (EGCG) on the proliferation of peripheral blood mononuclear cells

(2014) Farid Saleh et al.   BMC Complementary and Alternative Medicine

The Indoleamine 2,3-Dioxygenase Pathway Is Essential for Human Plasmacytoid Dendritic Cell-Induced Adaptive T Regulatory Cell Generation

(2014) W. Chen et al.   JOURNAL OF IMMUNOLOGY

Pro-apoptotic effect of Epigallo-catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-induced arthritis

(2012) Dandan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Itraconazole: Its possible role in inhibiting angiogenesis in Rheumatoid Arthritis

(2012) Asfandyar Sheikh et al.   MEDICAL HYPOTHESES

Developing an effective treatment algorithm for rheumatoid arthritis

(2012) E. C. Keystone et al.   RHEUMATOLOGY

Epigallocatechin-3-Gallate Ameliorates Experimental Autoimmune Encephalomyelitis by Altering Balance among CD4+ T-Cell Subsets

(2011) Junpeng Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Deficiency of Nrf2 Accelerates the Effector Phase of Arthritis and Aggravates Joint Disease

(2011) Nuria Maicas et al.   ANTIOXIDANTS & REDOX SIGNALING

Current Concepts of Hyperinflammation in Chronic Granulomatous Disease

(2011) Nikolaus Rieber et al.   Clinical & Developmental Immunology

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation

(2011) Pei-Yi Tsai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Induction of regulatory T cells by green tea polyphenol EGCG

(2011) Carmen P. Wong et al.   IMMUNOLOGY LETTERS

CD4+CD25highCD127low/- Treg Cell Frequency from Peripheral Blood Correlates with Disease Activity in Patients with Rheumatoid Arthritis

(2011) SHIN-YA KAWASHIRI et al.   JOURNAL OF RHEUMATOLOGY

Indoleamine 2,3-dioxygenase–expressing myeloid dendritic cells and macrophages in infectious and noninfectious cutaneous granulomas

(2011) Dagmar von Bubnoff et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The green tea polyphenol (−)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis

(2011) Ai Peng et al.   KIDNEY INTERNATIONAL

Green tea EGCG, T cells, and T cell-mediated autoimmune diseases

(2011) Dayong Wu et al.   MOLECULAR ASPECTS OF MEDICINE

Mechanical loading, cartilage degradation, and arthritis

(2010) Hui B. Sun   Annals of the New York Academy of Sciences

Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice

(2010) C. J. Wruck et al.   ANNALS OF THE RHEUMATIC DISEASES

Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction

(2010) So Youn Park et al.   ARTHRITIS AND RHEUMATISM

Epigallocatechin gallate delays the onset of type 1 diabetes in spontaneous non-obese diabetic mice

(2010) Zhuo Fu et al.   BRITISH JOURNAL OF NUTRITION

Intact indoleamine 2,3-dioxygenase activity in human chronic granulomatous disease

(2010) Birgit Jürgens et al.   CLINICAL IMMUNOLOGY

NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice

(2010) X. Kong et al.   JOURNAL OF IMMUNOLOGY

Green tea polyphenol epigallocatechi3-gallate: Inflammation and arthritis

(2010) Rashmi Singh et al.   LIFE SCIENCES

Green tea polyphenol epigallocatechin 3-gallate in arthritis: progress and promise

(2010) Salahuddin Ahmed   ARTHRITIS RESEARCH & THERAPY

Green tea EGCG suppresses T cell proliferation through impairment of IL-2/IL-2 receptor signaling

(2009) Dayong Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

CD4+CD25+regulatory T cells in autoimmune arthritis

(2009) Soyoung Oh et al.   IMMUNOLOGICAL REVIEWS

Epigallocatechin-3-gallate diminishes CCL2 expression in human osteoblastic cells via up-regulation of phosphatidylinositol 3-Kinase/Akt/Raf-1 interaction: A potential therapeutic benefit for arthritis

(2008) Sze-Kwan Lin et al.   ARTHRITIS AND RHEUMATISM

Dendritic cells modulated by innate immunity improve collagen-induced arthritis and induce regulatory T cellsin vivo

(2008) Olivier Jaen et al.   IMMUNOLOGY

Green Tea Protects Rats against Autoimmune Arthritis by Modulating Disease-Related Immune Events

(2008) Hong Ro Kim et al.   JOURNAL OF NUTRITION

Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren's syndrome, an autoimmune disease

(2008) Kevin Gillespie et al.   LIFE SCIENCES

Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model

(2008) Min-Jung Park et al.   ARTHRITIS RESEARCH & THERAPY