Article
Endocrinology & Metabolism
Travis Anderson, Gail Corneau, Laurie Wideman, Kari Eddington, Suzanne Vrshek-Schallhorn
Summary: The study found that prior day sleep duration and physical activity levels can interact to predict the cortisol awakening response (CAR) the following morning, with short sleep duration and high levels of physical activity resulting in an augmented CAR. The effects of sleep and physical activity on CAR demonstrate an interactive effect.
PSYCHONEUROENDOCRINOLOGY
(2021)
Article
Clinical Neurology
Amy G. Hartman, Sarah McKendry, Murat Akcakaya, Adriane Soehner, Stefanie C. Bodison, Dilhari DeAlmeida, Roxanna Bendixen
Summary: This study aimed to compare movement-based rest-activity rhythms (RARs) and sleep period variables of children with tactile hypersensitivities and non-sensitive peers. The results showed similar RARs and sleep variables between the two groups, but children with hypersensitivities took longer to fall asleep. The study provides preliminary data on sleep characteristics of children with tactile hypersensitivities and supports the use of wrist-worn actigraphy in future sleep studies.
Review
Clinical Neurology
Malgorzata Sobol, Agata Blachnio, Michal Meisner, Joanna Szyszkowska, Konrad S. Jankowski
Summary: This review examines the associations between sleep and circadian activity patterns during and after pregnancy and postpartum mental health factors. The systematic review and meta-analysis findings suggest that postpartum total sleep at night is closely related to postpartum fatigue and depression. However, more studies are needed to explore the associations between sleep-wake rhythm during pregnancy and postpartum mental health factors.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Ann-Sophie Loock, Ameena Khan Sullivan, Catia Reis, Teresa Paiva, Neda Ghotbi, Luisa K. Pilz, Anna M. Biller, Carmen Molenda, Maria T. Vuori-Brodowski, Till Roenneberg, Eva C. Winnebeck
Summary: The Munich Actimetry Sleep Detection Algorithm was evaluated for estimating sleep-wake patterns using wrist-locomotor activity recordings. The algorithm showed good performance in classifying sleep compared to sleep logs and had high sensitivity when compared to polysomnography results, although with lower specificity due to characteristics of the polysomnographic recordings. The algorithm provides an objective alternative to sleep logs for assessing sleep-wake patterns in field studies.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Obstetrics & Gynecology
Xiao-Juan Wang, Xiao-Ting Li, Na Chen, Long Huang, Shui-Xiu Huang, Ting-Ting Chen, Gui-Hua Liu, Rong-Fang Hu
Summary: This study aimed to investigate the mental health, sleep quality, and circadian rhythms of cortisol and melatonin secretion in pregnant women with threatened preterm labor (TPL). The study found that pregnant women with TPL had poorer sleep quality and disrupted circadian rhythm of melatonin secretion compared with normal pregnant women (NPW). However, there were no differences found in mental health (anxiety and depression) and circadian rhythm of cortisol secretion. Large-scale studies should be conducted to evaluate these changes in women with TPL.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Biochemistry & Molecular Biology
Sol Mochon-Benguigui, Almudena Carneiro-Barrera, Manuel Dote-Montero, Manuel J. Castillo, Francisco J. Amaro-Gahete
Summary: Sleep quality is not related to levels of plasma anabolic hormones, but to levels of catabolic hormones, in sedentary middle-aged adults. Changes in aging markers associated with sleep disturbances may be mediated by age-related changes in the catabolic endocrine system.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Clinical Neurology
Andre Comiran Tonon, Debora Barroggi Constantino, Guilherme Rodriguez Amando, Ana Carolina Abreu, Ana Paula Francisco, Melissa Alves Braga de Oliveira, Luisa K. Pilz, Nicoli Bertuol Xavier, Fernanda Rohrsetzer, Laila Souza, Jader Piccin, Arthur Caye, Sandra Petresco, Pedro H. Manfro, Rivka Pereira, Thais Martini, Brandon A. Kohrt, Helen L. Fisher, Valeria Mondelli, Christian Kieling, Maria Paz Loayza Hidalgo
Summary: This study aimed to investigate the circadian rhythms and sleep-wake behavior associated with MDD and high risk for MDD among adolescents. The results showed that adolescents with MDD exhibited more severe insomnia, shorter sleep duration, higher social jetlag, and higher exposure to artificial light at night compared to other groups. The HR group also showed similar problems. Therefore, preventive strategies should focus on sleep issues, and actimetry-based parameters may be promising tools for assessing depression in adolescence.
Article
Gastroenterology & Hepatology
Samantha Conley, Sangchoon Jeon, Vanessa Lehner, Deborah D. Proctor, Nancy S. Redeker
Summary: In a cross-sectional study of adults with IBD, disrupted RARs were found to be associated with GI symptoms. Further research is needed to better understand these associations and develop interventions to improve these characteristics in adults with IBD.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Sport Sciences
Luke Edinborough, Jessica Hill, Mark Jarvis, Stewart Bruce-Low, Charles R. Pedlar
Summary: This case study examines the sleep patterns of a 17.6-year-old professional football player who experienced excessive night-time awakenings. The player underwent subjective and objective sleep assessments, and a sleep hygiene intervention was prescribed based on the data. The results showed improved sleep quality and lower wake episodes compared to pre-intervention levels and reference data from a similar professional cohort.
JOURNAL OF SPORTS SCIENCES
(2023)
Review
Oncology
Annemarie D. Jagielo, Catherine Benedict, David Spiegel
Summary: Circadian, hormonal, and sleep rhythm disruptions are common concerns among cancer patients. Research shows that circadian rhythm disruption is associated with adverse mental health and disease outcomes. Chronomodulated chemotherapy, light therapy, cognitive behavioral therapy for insomnia, and physical activity have shown evidence of effectiveness in improving sleep and occasionally, disease outcomes.
FRONTIERS IN ONCOLOGY
(2023)
Article
Clinical Neurology
Ozge Ulgen, Hatice Ezgi Baris, Oyku Ozboru Askan, Selda Kucuk Akdere, Can Ilgin, Hulya Ozdemir, Nural Bekiroglu, Kivilcim Gucuyener, Eren Ozek, Perran Boran
Summary: The study found that actigraphy at a medium threshold can accurately depict the sleep of typically developing preterm infants in the NICU, and aEEG may be an alternative adjunctive method for evaluating sleep/wake states.
Article
Clinical Neurology
Hannah Scott, Bastien Lechat, Jack Manners, Nicole Lovato, Andrew Vakulin, Peter Catcheside, Danny J. Eckert, Amy C. Reynolds
Summary: Self-reported sleep difficulties are a major concern in the diagnosis and treatment of chronic insomnia. However, advancements in in-home sleep monitoring technology and the use of self-reported sleep outcomes can assist in managing insomnia. This review explores emerging techniques for objective sleep monitoring that could improve the identification and management of insomnia. Diagnostic techniques discussed include insomnia phenotyping, better detection of coexisting sleep disorders, and identifying high-risk patients. Treatment techniques examined include therapy administration, methods for assessing and improving treatment adherence, and sleep feedback. The capabilities of sleep devices and the need for further research are also discussed.
Article
Clinical Neurology
Megan McMahon, Yoshita Malneedi, Darrell A. Worthy, David M. Schnyer
Summary: This study found a significant association between rest-activity rhythm stability and white matter microstructure in healthy adults across different age groups, suggesting that rest-activity rhythm may serve as a biomarker of brain health throughout the adult lifespan.
Article
Multidisciplinary Sciences
Randi Liset, Janne Gronli, Roger E. Henriksen, Tone E. G. Henriksen, Roy M. Nilsen, Stale Pallesen
Summary: The prevalence of insomnia among pregnant women in the third trimester was 38%, with evening light exposure associated with shorter sleep duration. Pregnant women exhibited lower sleep efficiency and higher exposure to evening light compared to the non-pregnant group.
Article
Multidisciplinary Sciences
Ming Fei Li, Lavania Nagendran, Lauren Schroeder, David R. Samson
Summary: This study investigated the combined effects of biological, environmental, and human factors on the activity of sled dogs. The results showed that different factors had varying impacts on the daytime and nighttime activity of working and nonworking dogs, with human activity being the most influential factor on the activity of working dogs.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Pediatrics
Martin Poryo, Lilly Stock, Sarah Ruffing, Michael Zemlin, Sascha Meyer
KLINISCHE PADIATRIE
(2023)
Article
Clinical Neurology
Johannes M. Weller, Franziska Dorn, Julius N. Meissner, Sebastian Stoesser, Niklas M. Beckonert, Julia Nordsiek, Christine Kindler, Milani Deb-Chatterji, Gabor C. Petzold, Felix J. Bode
Summary: The study found that young stroke patients undergoing endovascular treatment (ET) had better outcomes compared to older patients, even when matched for prestroke condition, comorbidities, and stroke severity. Therefore, future studies may need to establish more liberal guidelines for performing ET in younger patients.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Clinical Neurology
Sebastian Stosser, Felix J. Bode, Julius N. Meissner, Johannes M. Weller, Christine Kindler, Malte Sauer, Daniel Paech, Christoph Riegler, Christian H. Nolte, Amitis Pourian, Joachim Rother, Nadja Selo, Ulrike Ernemann, Sven Poli, Rosa Marie Eckert, Georg Bohner, Korbinian Scherling, Franziska Dorn, Gabor C. Petzold
Summary: This study aimed to assess the impact of unknown time last known well on the outcome of endovascular treatment in patients with large vessel occlusion stroke. The results showed that patients with unknown time last known well had similar treatment outcomes after adjusting for confounders, suggesting that endovascular treatment should not be withheld if the time last known well is unknown.
CLINICAL NEURORADIOLOGY
(2023)
Article
Pediatrics
Elisabeth Kaiser, Regine Stutz, Sybelle Goedicke-Fritz, Michelle Bous, Michael Zemlin, Christian Adams
Summary: Premature infants are exposed to high sound levels, especially during non-invasive ventilation, with sound pressure levels increasing particularly in the non-physiological high-frequency range. An optimized design of the incubator can further reduce continuous sound exposure.
KLINISCHE PADIATRIE
(2023)
Article
Clinical Neurology
Erkan Celik, Lukas Goertz, Yigit Ozpeynirci, Marc Schlamann, Franziska Dorn, Nils Lehnen, Eberhard Siebert, Thomas Liebig, Christoph Kabbasch
Summary: A retrospective study compared the effectiveness of WEB embolization and standard coiling for treating ruptured basilar tip aneurysms. Both methods showed similar efficacy in preventing rebleeding, but WEB embolization required less stent-assistance, potentially beneficial for avoiding anti-platelet therapy in SAH patients.
Article
Clinical Neurology
Nils C. Lehnen, Daniel Paech, Stefan Zuelow, Felix J. Bode, Gabor C. Petzold, Alexander Radbruch, Franziska Dorn
Summary: In this study, we retrospectively analyzed the data of patients treated with the Nimbus stentretriever at our high-volume stroke center. The results showed that Nimbus had a favorable effect in handling fibrin-rich clots in endovascular stroke treatment.
CLINICAL NEURORADIOLOGY
(2023)
Article
Clinical Neurology
Daniel Paech, Nils Lehnen, Asadeh Lakghomi, Arndt Schievelkamp, Christian Gronemann, Felix J. Bode, Alexander Radbruch, Franziska Dorn
Summary: As the number of neurointerventional procedures increases, there is a growing demand for well-trained neurointerventionalists. This study aimed to establish and assess a systematic 3-step approach for acute stroke treatment, which includes simulator training and virtual supervision through remote streaming support (RESS). Five trainees who completed the 3-step approach evaluated the first training step (simulator) through an 11-item questionnaire. Additionally, all trainees and one supervisor answered a standardized questionnaire after the initial 15 consecutive thrombectomies for each trainee, totaling 75 thrombectomies. The simulator training provided learning benefits and increased confidence in performing the procedures on patients, while the RESS approach facilitated the translation to independent thrombectomies. Overall, this 3-step approach improves safety and may expedite the training of neurointerventionalists.
CLINICAL NEURORADIOLOGY
(2023)
Article
Clinical Neurology
Raquel Costa, Adrien M. Aubert, Anna-Veera Seppanen, Ulrika Aden, Iemke Sarrechia, Michael Zemlin, Marina Cuttini, Mairi Mannamaa, Veronique Pierrat, Arno van Heijst, Henrique Barros, Jennifer Zeitlin, Samantha Johnson
Summary: This study aimed to assess the accuracy of parent-reported gross motor impairment (GMI) at age 2 in predicting significant movement difficulties at age 5 in extremely preterm children. The results showed that parent reports of GMI at age 2 accurately classified movement difficulties at age 5 in most children. However, there were some cases where children with movement difficulties at age 5 were not identified at age 2.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Neuroimaging
Lukas Meyer, Christian Paul Stracke, Gabriel Broocks, Marta Wallocha, Mohamed Elsharkawy, Peter B. Sporns, Eike Piechowiak, Johannes Kaesmacher, Christian Maegerlein, Moritz Roman Hernandez Petzsche, Weis Naziri, Hanna Zimmermann, Nuran Abdullayev, Christoph Kabbasch, Daniel Behme, Maximilian Thormann, Volker Maus, Sebastian Fischer, Markus A. Moehlenbruch, Charlotte Sabine Weyland, Soenke Langner, Marielle Ernst, Ala Jamous, Dan Meila, Milena Miszczuk, Eberhard Siebert, Stephan Lowens, Lars Udo Krause, Leonard L. L. Yeo, Benjamin Y. Q. Tan, Anil Gopinathan, Benjamin Gory, Jorge Galvan Fernandez, Miguel Schueller Arteaga, Pedro Navia, Eytan Raz, Maksim Shapiro, Fabian Arnberg, Kamil Zelenak, Mario Martinez-Galdamez, Maria Alexandrou, Andreas Kastrup, Panagiotis Papanagiotou, Franziska Dorn, Andre Kemmling, Marios-Nikos Psychogios, Tommy Andersson, Rene Chapot, Jens Fiehler, Uta Hanning
Summary: This study compared the effect of anesthetic strategies on procedural, clinical, and safety outcomes of distal medium vessel occlusions (DMVOs) stroke thrombectomy. The study found that conscious sedation (CS) and general anesthesia (GA) resulted in similar rates of reperfusion and long-term functional outcomes for DMVOs of the anterior cerebral arteries (ACA) and posterior cerebral arteries (PCA), but GA was more effective in achieving complete reperfusion for DMVOs of the ACA.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lukas Meyer, Paul Stracke, Gabriel Broocks, Mohamed Elsharkawy, Peter Sporns, Eike Piechowiak, Johannes Kaesmacher, Christian Maegerlein, Moritz Roman Hernandez Petzsche, Hanna Zimmermann, Weis Naziri, Nuran Abdullayev, Christoph Kabbasch, Elie Diamandis, Maximilian Thormann, Volker Maus, Sebastian Fischer, Markus Moehlenbruch, Charlotte S. Weyland, Marielle Ernst, Ala Jamous, Dan Meila, Milena Miszczuk, Eberhard Siebert, Stephan Lowens, Lars Udo Krause, Leonard Yeo, Benjamin Tan, Anil Gopinathan, Juan F. Arenillas-Lara, Pedro Navia, Eytan Raz, Maksim Shapiro, Fabian Arnberg, Kamil Zelenak, Mario Martinez-Galdamez, Maria Alexandrou, Andreas Kastrup, Panagiotis Papanagiotou, Andre Kemmling, Franziska Dorn, Marios Psychogios, Tommy Andersson, Rene Chapot, Jens Fiehler, Uta Hanning
Summary: The study compared the clinical and safety outcomes of mechanical thrombectomy and best medical treatment for distal medium vessel occlusions of the anterior cerebral artery. The results showed no significant differences in early clinical outcomes, favorable functional recovery, and mortality between thrombectomy and best medical treatment. This suggests that thrombectomy is a safe and technically feasible treatment option.
Article
Acoustics
Paula Freundt, Nasenien Nourkami-Tutdibi, Erol Tutdibi, Paul Janzing, Thomas von Ostrowski, Martin Langer, Michael Zemlin, Johannes Steinhard
Summary: This study aimed to analyze the feasibility of using a high-end simulator with a randomly moving fetus for structured ultrasound simulation training (SIM-UT) in teaching second-trimester ultrasound screening. The results showed that novices significantly improved their ultrasound skills after 8 hours of training, reaching the level of physicians. After 12 hours of SIM-UT, the trial group performed faster than the physician group and obtained standard planes close to expert level.
ULTRASCHALL IN DER MEDIZIN
(2023)
Article
Nutrition & Dietetics
Cosima Zemlin, Laura Altmayer, Caroline Stuhlert, Julia Theresa Schleicher, Carolin Woermann, Marina Lang, Laura-Sophie Scherer, Ida Clara Thul, Lisanne Sophie Spenner, Jana Alisa Simon, Alina Wind, Elisabeth Kaiser, Regine Weber, Sybelle Goedicke-Fritz, Gudrun Wagenpfeil, Michael Zemlin, Erich-Franz Solomayer, Joerg Reichrath, Carolin Mueller
Summary: This study aimed to analyze serum 25-hydroxyvitamin D (25(OH)D) levels in newly diagnosed breast cancer patients and its association with prognostic and lifestyle factors. The results showed a common deficiency of vitamin D in breast cancer patients, but did not support the hypothesis that vitamin D deficiency may be a main prognostic factor for breast cancer.
Article
Economics
Franziska Dorn, Rosalba Radice, Giampiero Marra, Thomas Kneib
Summary: Empirical research on poverty today often considers multiple dimensions of well-being, including time-use, which is especially relevant to women's unpaid work. By constructing a bivariate poverty line based on income and leisure, we incorporate distributional regression into copula models to measure the vulnerability to poverty. Using data from the 2018 Mexican National Survey of Households, we find that the bidimensional poverty rate is 18 percentage points higher than the poverty rate calculated using separate time and income measures, highlighting the poverty of non-indigenous women.
REVIEW OF INCOME AND WEALTH
(2023)
Article
Biochemistry & Molecular Biology
Michelle Bous, Charline Schmitt, Muriel Charlotte Hans, Regine Weber, Nasenien Nourkami-Tutdibi, Sebastian Tenbruck, Bashar Haj Hamoud, Gudrun Wagenpfeil, Elisabeth Kaiser, Erich-Franz Solomayer, Michael Zemlin, Sybelle Goedicke-Fritz
Summary: The sex of the newborn may affect the lymphocyte subpopulations in cord blood, with higher frequencies of B cell counts in male newborns and higher counts of certain T cell subpopulations in female newborns. This indicates that sex may have a significant impact on the developing immune system, emphasizing the need for further research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Obstetrics & Gynecology
Paul Janzing, Nasenien Nourkami-Tutdibi, Erol Tutdibi, Paula Freundt, Thomas von Ostrowski, Martin Langer, Michael Zemlin, Johannes Steinhard
Summary: The purpose of this study was to analyze the learning curves of ultrasound novices in fetal echocardiography during structured simulation-based ultrasound training (SIM-UT). The results showed that the students consistently improved their ultrasound performance during the 6-week training program. After 6 weeks, they were able to reach the same skill level as the expert group in acquiring the AHA/ISUOG fetal echocardiography standard planes. SIM-UT is highly effective for learning fetal echocardiography.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)