Inhibition of MicroRNA 195 Prevents Apoptosis and Multiple-Organ Injury in Mouse Models of Sepsis

Sirt1 restrains lung inflammasome activation in a murine model of sepsis

(2015) Rong Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Silencing of miR-195 reduces diabetic cardiomyopathy in C57BL/6 mice

(2015) Dong Zheng et al.   DIABETOLOGIA

Novel Role of Resveratrol

(2014) Wei Xu et al.   SHOCK

MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment

(2013) Daniel Quiat et al.   JOURNAL OF CLINICAL INVESTIGATION

Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture

(2013) Shao-Chun Wu et al.   PLoS One

MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells

(2013) Y Zhou et al.   Cell Death & Disease

microRNA Regulation of Inflammatory Responses

(2012) Ryan M. O'Connell et al.   Annual Review of Immunology

Evidence for serum miR-15a and miR-16 levels as biomarkers that distinguish sepsis from systemic inflammatory response syndrome in human subjects

(2012) Huijuan Wang et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer

(2012) S T Guo et al.   ONCOGENE

Serum MicroRNA Signatures Identified by Solexa Sequencing Predict Sepsis Patients’ Mortality: A Prospective Observational Study

(2012) Huijuan Wang et al.   PLoS One

MicroRNA-195 Promotes Apoptosis in Mouse Podocytes via Enhanced Caspase Activity Driven by BCL2 Insufficiency

(2011) Yu-Qiang Chen et al.   AMERICAN JOURNAL OF NEPHROLOGY

MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1

(2011) Huaqing Zhu et al.   CARDIOVASCULAR RESEARCH

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

(2011) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 Prevents Apoptosis of Brain Endothelium during Bacteremia

(2011) D. Londono et al.   JOURNAL OF IMMUNOLOGY

Extracellular Administration of BCL2 Protein Reduces Apoptosis and Improves Survival in a Murine Model of Sepsis

(2011) Akiko Iwata et al.   PLoS One

Serum miR-146a and miR-223 as potential new biomarkers for sepsis

(2010) Jia-feng Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

(2010) Feifan Zhou et al.   FEBS Journal

Insights Into Sepsis Therapeutic Design Based on the Apoptotic Death Pathway

(2010) Yuichi Hattori et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Increased death receptor pathway of apoptotic signaling in septic mouse aorta: effect of systemic delivery of FADD siRNA

(2009) Naoyuki Matsuda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Silencing of Fas-associated Death Domain Protects Mice from Septic Lung Inflammation and Apoptosis

(2009) Naoyuki Matsuda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism*

(2009) Karel Tyml et al.   CRITICAL CARE MEDICINE

Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

(2009) E. Shen et al.   DIABETES

miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis

(2009) Can-Jie Guo et al.   JOURNAL OF HEPATOLOGY

The sepsis seesaw: tilting toward immunosuppression

(2009) Richard S Hotchkiss et al.   NATURE MEDICINE

A prospective, observational registry of patients with severe sepsis: The Canadian Sepsis Treatment and Response Registry*

(2008) Claudio M. Martin et al.   CRITICAL CARE MEDICINE

Docking Study Yields Four Novel Inhibitors of the Protooncogene Pim-1 Kinase†

(2008) Albert C. Pierce et al.   JOURNAL OF MEDICINAL CHEMISTRY