Readers of PCNA modifications

ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin

(2013) Kyoo-young Lee et al.   JOURNAL OF CELL BIOLOGY

The Elg1 Replication Factor C-like Complex Functions in PCNA Unloading during DNA Replication

(2013) Takashi Kubota et al.   MOLECULAR CELL

Phosphorylation at tyrosine 114 of Proliferating Cell Nuclear Antigen (PCNA) is required for adipogenesis in response to high fat diet

(2012) Yuan-Hung Lo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Spartan/C1orf124 is important to prevent UV-induced mutagenesis

(2012) Yuka Machida et al.   CELL CYCLE

ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response

(2012) R. Weston et al.   GENES & DEVELOPMENT

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

Epidermal Growth Factor Receptor Protects Proliferating Cell Nuclear Antigen from Cullin 4A Protein-mediated Proteolysis

(2012) Yuan-Hung Lo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proliferating Cell Nuclear Antigen (PCNA)-binding Protein C1orf124 Is a Regulator of Translesion Synthesis

(2012) Gargi Ghosal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsic Flexibility of Ubiquitin on Proliferating Cell Nuclear Antigen (PCNA) in Translesion Synthesis

(2012) Richard G. Hibbert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Replication-Independent Repair of DNA Interstrand Crosslinks

(2012) Hannah L. Williams et al.   MOLECULAR CELL

Spartan/C1orf124, a Reader of PCNA Ubiquitylation and a Regulator of UV-Induced DNA Damage Response

(2012) Richard C. Centore et al.   MOLECULAR CELL

Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks

(2012) Stephanie Panier et al.   MOLECULAR CELL

The HARP-like Domain-Containing Protein AH2/ZRANB3 Binds to PCNA and Participates in Cellular Response to Replication Stress

(2012) Jingsong Yuan et al.   MOLECULAR CELL

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress

(2012) Alberto Ciccia et al.   MOLECULAR CELL

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

(2012) Anthony A. Armstrong et al.   NATURE

DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage

(2012) Emily J Davis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

(2012) Anna Mosbech et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance

(2012) Szilvia Juhasz et al.   NUCLEIC ACIDS RESEARCH

Homologous recombination and its regulation

(2012) L. Krejci et al.   NUCLEIC ACIDS RESEARCH

Role of SUMO modification of human PCNA at stalled replication fork

(2012) Himabindu Gali et al.   NUCLEIC ACIDS RESEARCH

A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA

(2012) Joanne L. Parker et al.   NUCLEIC ACIDS RESEARCH

Reversal of PCNA Ubiquitylation by Ubp10 in Saccharomyces cerevisiae

(2012) Alfonso Gallego-Sánchez et al.   PLoS Genetics

The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

(2011) S. A. Williams et al.   BLOOD

Elg1, the major subunit of an alternative RFC complex, interacts with SUMO-processing proteins

(2011) Oren Parnas et al.   CELL CYCLE

Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition

(2011) Komaraiah Palle et al.   CELL CYCLE

CRL4Cdt2

(2011) Tarek Abbas et al.   CELL CYCLE

Ubiquitylation and the Fanconi anemia pathway

(2011) Elizabeth Garner et al.   FEBS LETTERS

Regulation of the Fanconi anemia pathway by a SUMO-like delivery network

(2011) K. Yang et al.   GENES & DEVELOPMENT

The Non-canonical Protein Binding Site at the Monomer-Monomer Interface of Yeast Proliferating Cell Nuclear Antigen (PCNA) Regulates the Rev1-PCNA Interaction and Polζ/Rev1-dependent Translesion DNA Synthesis

(2011) Neeru M. Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI

(2011) George-Lucian Moldovan et al.   MOLECULAR CELL

The genome maintenance factor Mgs1 is targeted to sites of replication stress by ubiquitylated PCNA

(2011) Irene Saugar et al.   NUCLEIC ACIDS RESEARCH

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

(2011) Ayal Hendel et al.   PLoS Genetics

FANCD2 monoubiquitination provides a link between the HHR6 and FA-BRCA pathways

(2010) Jun Zhang et al.   CELL CYCLE

Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe

(2010) Sharada Ramasubramanyan et al.   DNA REPAIR

The unusual UBZ domain of Saccharomyces cerevisiae polymerase η

(2010) Rachel V. Woodruff et al.   DNA REPAIR

Srs2: The “Odd-Job Man” in DNA repair

(2010) Victoria Marini et al.   DNA REPAIR

Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA

(2010) Oren Parnas et al.   EMBO JOURNAL

Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway

(2010) Ihn Young Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human ELG1 Regulates the Level of Ubiquitinated Proliferating Cell Nuclear Antigen (PCNA) through Its Interactions with PCNA and USP1

(2010) Kyoo-young Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAD18-dependent Recruitment of SNM1A to DNA Repair Complexes by a Ubiquitin-binding Zinc Finger

(2010) Kailin Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network

(2010) Liyi Geng et al.   JOURNAL OF CELL BIOLOGY

DNA Replication-Coupled PCNA Mono-Ubiquitination and Polymerase Switching in a Human In Vitro System

(2010) Yuji Masuda et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen

(2010) Bret D. Freudenthal et al.   JOURNAL OF MOLECULAR BIOLOGY

Unconventional Ubiquitin Recognition by the Ubiquitin-Binding Motif within the Y Family DNA Polymerases ι and Rev1

(2010) Martha G. Bomar et al.   MOLECULAR CELL

Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination

(2010) Marzena Bienko et al.   MOLECULAR CELL

Yeast evolutionary genomics

(2010) Bernard Dujon   NATURE REVIEWS GENETICS

Ubiquitin signalling in DNA replication and repair

(2010) Helle D. Ulrich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

(2010) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Convergence of Rad6/Rad18 and Fanconi Anemia Tumor Suppressor Pathways upon DNA Damage

(2010) Hwan Ki Park et al.   PLoS One

Annealing helicase 2 (AH2), a DNA-rewinding motor with an HNH motif

(2010) T. Yusufzai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA polymerase   lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells

(2010) N. Acharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains

(2010) Shengkai Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Establishment of Sister Chromatid Cohesion

(2009) Robert V. Skibbens   CURRENT BIOLOGY

Regulating post-translational modifications of the eukaryotic replication clamp PCNA

(2009) Helle D. Ulrich   DNA REPAIR

Ubiquitin-binding domains and their role in the DNA damage response

(2009) Kay Hofmann   DNA REPAIR

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80

(2009) Yusuke Sato et al.   EMBO JOURNAL

Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen

(2009) Asami Hishiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Interaction between the Fanconi Anemia D2 Protein and Proliferating Cell Nuclear Antigen (PCNA) via a Conserved Putative PCNA Interaction Motif

(2009) Niall G. Howlett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proliferating Cell Nuclear Antigen Is Protected from Degradation by Forming a Complex with MutT Homolog2

(2009) Yu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a novel, widespread, and functionally important PCNA-binding motif

(2009) Karin M. Gilljam et al.   JOURNAL OF CELL BIOLOGY

Differential Roles for DNA Polymerases Eta, Zeta, and REV1 in Lesion Bypass of Intrastrand versus Interstrand DNA Cross-Links

(2009) J. K. Hicks et al.   MOLECULAR AND CELLULAR BIOLOGY

Principles of ubiquitin and SUMO modifications in DNA repair

(2009) Steven Bergink et al.   NATURE

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

(2009) Yogesh Kulathu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ubiquitin-binding motif of human DNA polymerase η is required for correct localization: Fig. 1.

(2009) Simone Sabbioneda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage

(2008) Thomas Göhler et al.   DNA REPAIR

Role of DNA polymerases η, ι and ζ in UV resistance and UV-induced mutagenesis in a human cell line

(2008) Quentin Gueranger et al.   DNA REPAIR

SUMO modification of PCNA is controlled by DNA

(2008) Joanne L Parker et al.   EMBO JOURNAL

Human Wrnip1 Is Localized in Replication Factories in a Ubiquitin-binding Zinc Finger-dependent Manner

(2008) Nicola Crosetto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

(2008) Arno F. Alpi et al.   MOLECULAR CELL

Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

(2008) Adelina A. Davies et al.   MOLECULAR CELL

PCNA Ubiquitination and REV1 Define Temporally Distinct Mechanisms for Controlling Translesion Synthesis in the Avian Cell Line DT40

(2008) Charlotte E. Edmunds et al.   MOLECULAR CELL

Srs2 removes deadly recombination intermediates independently of its interaction with SUMO-modified PCNA

(2008) C. Le Breton et al.   NUCLEIC ACIDS RESEARCH

Arabidopsis thalianaY-family DNA polymerase η catalyses translesion synthesis and interacts functionally with PCNA2

(2008) Heather J. Anderson et al.   PLANT JOURNAL

Regulation of polymerase exchange between Pol  and Pol  by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme

(2008) Z. Zhuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

(2008) A. Niimi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase   in translesion DNA synthesis

(2008) N. Acharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA