DNA double-strand break repair in Caenorhabditis elegans

Importance of the cell cycle phase for the choice of the appropriate DSB repair pathway, for genome stability mintenance: the trans-S double-strand break repair model

(2010) Fabien Delacôte et al.   CELL CYCLE

Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes

(2010) Young-Hoon Kang et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Roles of Werner syndrome protein in protection of genome integrity

(2010) Marie L. Rossi et al.   DNA REPAIR

Rad54, the motor of homologous recombination

(2010) Alexander V. Mazin et al.   DNA REPAIR

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

(2010) Sophie E Polo et al.   EMBO JOURNAL

Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair

(2010) Kamila Czornak et al.   JOURNAL OF APPLIED GENETICS

Overlapping Roles for Yen1 and Mus81 in Cellular Holliday Junction Processing

(2010) Ye Dee Tay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processing of Meiotic DNA Double Strand Breaks Requires Cyclin-dependent Kinase and Multiple Nucleases

(2010) Nicola Manfrini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage

(2010) Godelieve Smeenk et al.   JOURNAL OF CELL BIOLOGY

Mutations in Caenorhabditis elegans him-19 Show Meiotic Defects That Worsen with Age

(2010) Lois Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Overlapping Mechanisms Promote Postsynaptic RAD-51 Filament Disassembly during Meiotic Double-Strand Break Repair

(2010) Jordan D. Ward et al.   MOLECULAR CELL

Double Holliday junctions are intermediates of DNA break repair

(2010) Malgorzata Bzymek et al.   NATURE

NHEJ and its backup pathways in chromosomal translocations

(2010) Michael R Lieber   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA resection in eukaryotes: deciding how to fix the break

(2010) Pablo Huertas   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RTEL-1 Enforces Meiotic Crossover Interference and Homeostasis

(2010) J. L. Youds et al.   SCIENCE

The Caenorhabditis elegans Werner Syndrome Protein Functions Upstream of ATR and ATM in Response to DNA Replication Inhibition and Double-Strand DNA Breaks

(2010) Se-Jin Lee et al.   PLoS Genetics

The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair

(2010) Aymeric P. Bailly et al.   PLoS Genetics

Structural Maintenance of Chromosomes (SMC) Proteins Promote Homolog-Independent Recombination Repair in Meiosis Crucial for Germ Cell Genomic Stability

(2010) Jeremy S. Bickel et al.   PLoS Genetics

Cohesin: Its Roles and Mechanisms

(2009) Kim Nasmyth et al.   Annual Review of Genetics

The search for a human Holliday junction resolvase

(2009) Stephen C. West   BIOCHEMICAL SOCIETY TRANSACTIONS

Breaking Up Just Got Easier to Do

(2009) Hannah L. Klein et al.   CELL

Meiotic Chromosome Homology Search Involves Modifications of the Nuclear Envelope Protein Matefin/SUN-1

(2009) Alexandra M. Penkner et al.   CELL

Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair

(2009) Jennifer M. Svendsen et al.   CELL

Cytoskeletal Forces Span the Nuclear Envelope to Coordinate Meiotic Chromosome Pairing and Synapsis

(2009) Aya Sato et al.   CELL

Condensins Regulate Meiotic DNA Break Distribution, thus Crossover Frequency, by Controlling Chromosome Structure

(2009) David G. Mets et al.   CELL

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

(2009) Samira Fekairi et al.   CELL

MRN and the race to the break

(2009) Agnieszka Rupnik et al.   CHROMOSOMA

A Robust Network of Double-Strand Break Repair Pathways Governs Genome Integrity during C. elegans Development

(2009) Daphne B. Pontier et al.   CURRENT BIOLOGY

The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans

(2009) Bettina Meier et al.   EMBO JOURNAL

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

The axial element protein HTP-3 promotes cohesin loading and meiotic axis assembly in C. elegans to implement the meiotic program of chromosome segregation

(2009) A. F. Severson et al.   GENES & DEVELOPMENT

Meiotic DNA Double-Strand Break Repair Requires Two Nucleases, MRN and Ctp1, To Produce a Single Size Class of Rec12 (Spo11)-Oligonucleotide Complexes

(2009) N. Milman et al.   MOLECULAR AND CELLULAR BIOLOGY

Drosophila MUS312 and the Vertebrate Ortholog BTBD12 Interact with DNA Structure-Specific Endonucleases in DNA Repair and Recombination

(2009) Sabrina L. Andersen et al.   MOLECULAR CELL

Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair

(2009) Ivan M. Muñoz et al.   MOLECULAR CELL

A heavyweight joins the fray

(2009) Simon J. Boulton   NATURE

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle

(2009) Maximina H. Yun et al.   NATURE

Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans

(2009) Carolyn M. Phillips et al.   NATURE CELL BIOLOGY

BRCA1 and its toolbox for the maintenance of genome integrity

(2009) Michael S.Y. Huen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Polo-like kinases: conservation and divergence in their functions and regulation

(2009) Vincent Archambault et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant

(2009) Alexander Lorenz et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

(2009) Emma Bolderson et al.   NUCLEIC ACIDS RESEARCH

Caenorhabditis elegans HIM-18/SLX-4 Interacts with SLX-1 and XPF-1 and Maintains Genomic Integrity in the Germline by Processing Recombination Intermediates

(2009) Takamune T. Saito et al.   PLoS Genetics

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

(2008) Louise J. Barber et al.   CELL

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

HTP-3 Links DSB Formation with Homolog Pairing and Crossing Over during C. elegans Meiosis

(2008) William Goodyer et al.   DEVELOPMENTAL CELL

BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair

(2008) Adele Adamo et al.   EMBO REPORTS

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

(2008) S. Gravel et al.   GENES & DEVELOPMENT

Meiotic crossover number and distribution are regulated by a dosage compensation protein that resembles a condensin subunit

(2008) C. J. Tsai et al.   GENES & DEVELOPMENT

Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis

(2008) A. Sourirajan et al.   GENES & DEVELOPMENT

RecQ Helicase, Sgs1, and XPF Family Endonuclease, Mus81-Mms4, Resolve Aberrant Joint Molecules during Meiotic Recombination

(2008) Steve D. Oh et al.   MOLECULAR CELL

Mus81/Mms4 Endonuclease and Sgs1 Helicase Collaborate to Ensure Proper Recombination Intermediate Metabolism during Meiosis

(2008) Lea Jessop et al.   MOLECULAR CELL

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

CDK targets Sae2 to control DNA-end resection and homologous recombination

(2008) Pablo Huertas et al.   NATURE

Identification of Holliday junction resolvases from humans and yeast

(2008) Stephen C. Y. Ip et al.   NATURE

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

(2008) A. V. Nimonkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks

(2008) L. J. Reid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS

CRA-1 Uncovers a Double-Strand Break-Dependent Pathway Promoting the Assembly of Central Region Proteins on Chromosome Axes During C. elegans Meiosis

(2008) Sarit Smolikov et al.   PLoS Genetics

ATM Promotes the Obligate XY Crossover and both Crossover Control and Chromosome Axis Integrity on Autosomes

(2008) Marco Barchi et al.   PLoS Genetics

ZHP-3 Acts at Crossovers to Couple Meiotic Recombination with Synaptonemal Complex Disassembly and Bivalent Formation in C. elegans

(2008) Needhi Bhalla et al.   PLoS Genetics