Determination of T-2 and HT-2 Toxins in Traditional Chinese Medicine Marketed in China by LC-ELSD after Sample Clean-Up by Two Solid-Phase Extractions

LC-ELSD has been applied for the determination of T-2 and HT-2 toxins in Traditional Chinese Medicine (TCM) marketed in China. For sample preparation, two clean-up procedures were developed using Florisil and MycoSep227 for solid-phase extraction. Limits of detection (10 ng g(-1)) as well as recoveries are described. A total of 138 samples of 46 commercially available TCM samples was analyzed; only one sample was determined to contain T-2 at a level of 64.0 ng g(-1), and positive results were further confirmed by LC-ESI-MS-MS.