Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis

Transforming dietary peptides in promising lead compounds: the case of bioavailable carnosine analogs

(2012) Giulio Vistoli et al.   AMINO ACIDS

Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety

(2011) Nicholas A. Meanwell   CHEMICAL RESEARCH IN TOXICOLOGY

Chemodiversity and molecular plasticity: recognition processes as explored by property spaces

(2011) Giulio Vistoli et al.   Future Medicinal Chemistry

What has polar surface area ever done for drug discovery?

(2011) David E Clark   Future Medicinal Chemistry

Hydrophobicity of Peptides Containing D-Amino Acids

(2010) Toratane Munegumi   CHEMISTRY & BIODIVERSITY

The graphical representation of ADME-related molecule properties for medicinal chemists

(2010) Timothy J. Ritchie et al.   DRUG DISCOVERY TODAY

Lipophilicity and Its Relationship with Passive Drug Permeation

(2010) Xiangli Liu et al.   PHARMACEUTICAL RESEARCH

A sensitive and specific precursor ion scanning approach in liquid chromatography/electrospray ionization tandem mass spectrometry to detect methylprednisolone acetate and its metabolites in rat urine

(2010) Alessia Panusa et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution

(2009) Yveline Henchoz et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Recent Advances in Physicochemical and ADMET Profiling in Drug Discovery

(2009) Jianling Wang et al.   CHEMISTRY & BIODIVERSITY

Partition Coefficient and Molecular Flexibility: The Concept of Lipophilicity Space

(2009) Giulio Vistoli et al.   CHEMISTRY & BIODIVERSITY

Design, Synthesis, and Evaluation of Carnosine Derivatives as Selective and Efficient Sequestering Agents of Cytotoxic Reactive Carbonyl Species

(2009) Giulio Vistoli et al.   ChemMedChem

Exploring enantioselective molecular recognition mechanisms with chemoinformatic techniques

(2009) Alberto Del Rio   JOURNAL OF SEPARATION SCIENCE

In Vitro Solubility Assays in Drug Discovery

(2008) Edward Kerns et al.   CURRENT DRUG METABOLISM

Assessing drug-likeness – what are we missing?

(2008) Giulio Vistoli et al.   DRUG DISCOVERY TODAY

Calculation of Molecular Lipophilicity: State-of-the-Art and Comparison of LogP Methods on more than 96,000 Compounds

(2008) Raimund Mannhold et al.   JOURNAL OF PHARMACEUTICAL SCIENCES