Branched chain amino acids and metabolic regulation

Peripheral oxytocin treatment ameliorates obesity by reducing food intake and visceral fat mass

(2016) Yuko Maejima et al.   Aging-US

S6K1 in the Central Nervous System Regulates Energy Expenditure via MC4R/CRH Pathways in Response to Deprivation of an Essential Amino Acid

(2012) T. Xia et al.   DIABETES

FoxO1 Protein Cooperates with ATF4 Protein in Osteoblasts to Control Glucose Homeostasis

(2012) Aruna Kode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway

(2012) Jie Cao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Isoleucine or valine deprivation stimulates fat loss via increasing energy expenditure and regulating lipid metabolism in WAT

(2011) Ying Du et al.   AMINO ACIDS

ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosis

(2011) Houkai Li et al.   BIOCHEMICAL JOURNAL

Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways

(2011) Fei Xiao et al.   DIABETES

Leucine Deprivation Stimulates Fat Loss via Increasing CRH Expression in the Hypothalamus and Activating The Sympathetic Nervous System

(2011) Ying Cheng et al.   MOLECULAR ENDOCRINOLOGY

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Characteristics of Obesity and Its Related Disorders in China

(2010) Wei-Ping JIA et al.   BIOMEDICAL AND ENVIRONMENTAL SCIENCES

ATF4 regulates lipid metabolism and thermogenesis

(2010) Chunxia Wang et al.   CELL RESEARCH

Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver

(2010) Nobito Higuchi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Prevalence of Diabetes among Men and Women in China

(2010) Wenying Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Amino Acid Availability Controls TRB3 Transcription in Liver through the GCN2/eIF2α/ATF4 Pathway

(2010) Valérie Carraro et al.   PLoS One

Hypothalamic nutrient sensing in the control of energy homeostasis

(2009) Clémence Blouet et al.   BEHAVIOURAL BRAIN RESEARCH

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Atf4 Regulates Obesity, Glucose Homeostasis, and Energy Expenditure

(2009) J. Seo et al.   DIABETES

Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue

(2009) Y. Cheng et al.   DIABETES

Leucine modulates contraction- and insulin-stimulated glucose transport and upstream signaling events in rat skeletal muscle

(2009) Nobumasa Iwanaka et al.   JOURNAL OF APPLIED PHYSIOLOGY

The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts

(2009) Tatsuya Yoshizawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Leucine Supplementation of Drinking Water Does Not Alter Susceptibility to Diet-Induced Obesity in Mice

(2009) Ali Nairizi et al.   JOURNAL OF NUTRITION

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

The sensing of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but not rapamycin

(2009) S. Hao et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Epidemiology of non-alcoholic fatty liver disease in China

(2008) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY