Leveraging ecological theory to guide natural product discovery

Plant-endophyte symbiosis, an ecological perspective

(2015) Zahoor Ahmed Wani et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Rhizoxin Analogs Contribute to the Biocontrol Activity of a Newly Isolated Pseudomonas Strain

(2015) Kasumi Takeuchi et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Nonribosomal Peptides, Key Biocontrol Components for Pseudomonas fluorescens In5, Isolated from a Greenlandic Suppressive Soil

(2015) Charlotte F. Michelsen et al.   mBio

Global biogeographic sampling of bacterial secondary metabolism

(2015) Zachary Charlop-Powers et al.   eLife

Strain-Level Diversity of Secondary Metabolism in Streptomyces albus

(2015) Ryan F. Seipke   PLoS One

The Biogeography of Putative Microbial Antibiotic Production

(2015) Hélène Morlon et al.   PLoS One

Population Genetic Analysis of Streptomyces albidoflavus Reveals Habitat Barriers to Homologous Recombination in the Diversification of Streptomycetes

(2014) Kun Cheng et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolite induction via microorganism co-culture: A potential way to enhance chemical diversity for drug discovery

(2014) Samuel Bertrand et al.   BIOTECHNOLOGY ADVANCES

Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic origin

(2014) James R Doroghazi et al.   BMC GENOMICS

Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters

(2014) Peter Cimermancic et al.   CELL

Global biogeography ofStreptomycesantibiotic inhibition, resistance, and resource use

(2014) Daniel C. Schlatter et al.   FEMS MICROBIOLOGY ECOLOGY

Nutrient overlap, genetic relatedness and spatial origin influence interaction-mediated shifts in inhibitory phenotype amongStreptomycesspp.

(2014) Patricia Vaz Jauri et al.   FEMS MICROBIOLOGY ECOLOGY

Host-specificity among abundant and rare taxa in the sponge microbiome

(2014) Julie Reveillaud et al.   ISME Journal

Mullinamides A and B, new cyclopeptides produced by the Ruth Mullins coal mine fire isolate Streptomyces sp. RM-27-46

(2014) Xiachang Wang et al.   JOURNAL OF ANTIBIOTICS

Strain Prioritization for Natural Product Discovery by a High-Throughput Real-Time PCR Method

(2014) Hindra et al.   JOURNAL OF NATURAL PRODUCTS

Co-Cultivation—A Powerful Emerging Tool for Enhancing the Chemical Diversity of Microorganisms

(2014) Andreas Marmann et al.   Marine Drugs

Marine natural products

(2014) John W. Blunt et al.   NATURAL PRODUCT REPORTS

Diversity, abundance and natural products of marine sponge-associated actinomycetes

(2014) Usama Ramadan Abdelmohsen et al.   NATURAL PRODUCT REPORTS

An environmental bacterial taxon with a large and distinct metabolic repertoire

(2014) Micheal C. Wilson et al.   NATURE

A roadmap for natural product discovery based on large-scale genomics and metabolomics

(2014) James R Doroghazi et al.   Nature Chemical Biology

Explaining microbial genomic diversity in light of evolutionary ecology

(2014) Otto X. Cordero et al.   NATURE REVIEWS MICROBIOLOGY

Chemical-biogeographic survey of secondary metabolism in soil

(2014) Z. Charlop-Powers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angucyclines as signals modulate the behaviors of Streptomyces coelicolor

(2014) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ordering microbial diversity into ecologically and genetically cohesive units

(2014) B. Jesse Shapiro et al.   TRENDS IN MICROBIOLOGY

Bacterial seed endophytes: genera, vertical transmission and interaction with plants

(2014) Sascha Truyens et al.   Environmental Microbiology Reports

Endophytic Streptomyces sp. Y3111 from traditional Chinese medicine produced antitubercular pluramycins

(2013) Miaomiao Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Defensive microbial symbionts in Hymenoptera

(2013) Martin Kaltenpoth et al.   FUNCTIONAL ECOLOGY

Getting to the bottom of Taxol biosynthesis by fungi

(2013) Uwe Heinig et al.   FUNGAL DIVERSITY

Sympatric inhibition and niche differentiation suggest alternative coevolutionary trajectories among Streptomycetes

(2013) Linda L Kinkel et al.   ISME Journal

Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2

(2013) Khaled A Shaaban et al.   JOURNAL OF ANTIBIOTICS

Two Novel Hepatocellular Carcinoma Cycle Inhibitory Cyclodepsipeptides from a Hydrothermal Vent Crab-Associated Fungus Aspergillus clavatus C2WU

(2013) Wei Jiang et al.   Marine Drugs

Bacterial taxa-area and distance-decay relationships in marine environments

(2013) L. Zinger et al.   MOLECULAR ECOLOGY

Ruthmycin, a New Tetracyclic Polyketide from Streptomyces sp. RM-4-15

(2013) Xiachang Wang et al.   ORGANIC LETTERS

Subinhibitory Antibiotic Concentrations Mediate Nutrient Use and Competition among Soil Streptomyces

(2013) Patricia Vaz Jauri et al.   PLoS One

Plant monocultures produce more antagonistic soil Streptomyces communities than high-diversity plant communities

(2013) Matthew G. Bakker et al.   SOIL BIOLOGY & BIOCHEMISTRY

Interspecies Interactions Stimulate Diversification of the Streptomyces coelicolor Secreted Metabolome

(2013) M. F. Traxler et al.   mBio

Concentration-dependent activity in natural environments

(2013) Steve P. Bernier et al.   Frontiers in Microbiology

The Population Structure of Antibiotic-Producing Bacterial Symbionts of Apterostigma dentigerum Ants: Impacts of Coevolution and Multipartite Symbiosis

(2012) Eric J. Caldera et al.   AMERICAN NATURALIST

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Ammonificins C and D, Hydroxyethylamine Chromene Derivatives from a Cultured Marine Hydrothermal Vent Bacterium, Thermovibrio ammonificans

(2012) Eric H. Andrianasolo et al.   Marine Drugs

Predicting bacterial community assemblages using an artificial neural network approach

(2012) Peter E Larsen et al.   NATURE METHODS

Genomic insights into the marine sponge microbiome

(2012) Ute Hentschel et al.   NATURE REVIEWS MICROBIOLOGY

Antibiotic Resistance Is Prevalent in an Isolated Cave Microbiome

(2012) Kirandeep Bhullar et al.   PLoS One

Streptomyces competition and co-evolution in relation to plant disease suppression

(2012) Linda L. Kinkel et al.   RESEARCH IN MICROBIOLOGY

Ecological Populations of Bacteria Act as Socially Cohesive Units of Antibiotic Production and Resistance

(2012) O. X. Cordero et al.   SCIENCE

Population Genomics of Early Events in the Ecological Differentiation of Bacteria

(2012) B. J. Shapiro et al.   SCIENCE

A Coevolutionary Framework for Managing Disease-Suppressive Soils

(2011) Linda L. Kinkel et al.   Annual Review of Phytopathology

Rare actinomycetes: a potential storehouse for novel antibiotics

(2011) Kavita Tiwari et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Actinopolysporins A–C and Tubercidin as a Pdcd4 Stabilizer from the Halophilic ActinomyceteActinopolyspora erythraeaYIM 90600

(2011) Li-Xing Zhao et al.   JOURNAL OF NATURAL PRODUCTS

Chemical Analyses of Wasp-Associated Streptomyces Bacteria Reveal a Prolific Potential for Natural Products Discovery

(2011) Michael Poulsen et al.   PLoS One

Drivers of bacterial  -diversity depend on spatial scale

(2011) J. B. H. Martiny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the Rhizosphere Microbiome for Disease-Suppressive Bacteria

(2011) R. Mendes et al.   SCIENCE

Biodiversity, bioactive natural products and biotechnological potential of plant-associated endophytic actinobacteria

(2010) Sheng Qin et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Naphthospironone A: An Unprecedented and Highly Functionalized Polycyclic Metabolite from an Alkaline Mine Waste Extremophile

(2010) Zhang-Gui Ding et al.   CHEMISTRY-A EUROPEAN JOURNAL

Current approaches to exploit actinomycetes as a source of novel natural products

(2010) Olga Genilloud et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis

(2009) Dong-Chan Oh et al.   Nature Chemical Biology

Bacterial competition: surviving and thriving in the microbial jungle

(2009) Michael E. Hibbing et al.   NATURE REVIEWS MICROBIOLOGY

Mycangimycin, a Polyene Peroxide from a MutualistStreptomycessp.

(2009) Dong-Chan Oh et al.   ORGANIC LETTERS

Stress tolerance in plants via habitat-adapted symbiosis

(2008) Rusty J Rodriguez et al.   ISME Journal

Subinhibitory Concentrations of Antibiotics Induce Phenazine Production in a MarineStreptomycessp.

(2008) Maya I. Mitova et al.   JOURNAL OF NATURAL PRODUCTS

Deep-sea natural products

(2008) Danielle Skropeta   NATURAL PRODUCT REPORTS

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

(2008) TuAnh Nguyen et al.   NATURE BIOTECHNOLOGY