A Photoactivatable Platinum(IV) Complex Targeting Genomic DNA and Histone Deacetylases

New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells

(2015) Vojtech Novohradsky et al.   BIOCHEMICAL PHARMACOLOGY

Cellular Accumulation, Lipophilicity and Photocytotoxicity of Diazido Platinum(IV) Anticancer Complexes

(2014) Ana M. Pizarro et al.   ChemMedChem

Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands

(2014) Vojtech Novohradsky et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

De Novo Generation of Singlet Oxygen and Ammine Ligands by Photoactivation of a Platinum Anticancer Complex

(2013) Yao Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts

(2013) Yao Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Effect of a Monofunctional Phenanthriplatin-DNA Adduct on RNA Polymerase II Transcriptional Fidelity and Translesion Synthesis

(2013) Matthew W. Kellinger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer

(2012) Himashinie V.K. Diyabalanage et al.   CANCER LETTERS

Tryptophan Switch for a Photoactivated Platinum Anticancer Complex

(2012) Jennifer S. Butler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Suberoyl bishydroxamic acid-induced apoptosis in HeLa cells via ROS-independent, GSH-dependent manner

(2012) Bo Ra You et al.   MOLECULAR BIOLOGY REPORTS

Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: A Light-Activated Antitumor Platinum Complex That Kills Human Cancer Cells by an Apoptosis-Independent Mechanism

(2012) A. F. Westendorf et al.   MOLECULAR CANCER THERAPEUTICS

Platinum–DNA interstrand crosslinks: Molecular determinants of bending and unwinding of the double helix

(2011) Tereza Suchánková et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Suberoyl bishydroxamic acid inhibits the growth of A549 lung cancer cells via caspase-dependent apoptosis

(2010) Bo Ra You et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Suberoyl bis-hydroxamic acid induces p53-dependent apoptosis of MCF-7 breast cancer cells

(2009) Zhi-gang Zhuang et al.   ACTA PHARMACOLOGICA SINICA

HDAC inhibitors, MS275 and SBHA, enhances cytotoxicity induced by oxaliplatin in the colorectal cancer cell lines

(2009) Sylwia Flis et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity

(2009) Darren Griffith et al.   CHEMICAL COMMUNICATIONS

Photocytotoxictrans-Diam(m)ine Platinum(IV) Diazido Complexes More Potent than TheircisIsomers

(2009) Nicola J. Farrer et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Inhibition of transcription by platinum antitumor compounds

(2009) Ryan C. Todd et al.   Metallomics

Suberoyl Bis-Hydroxamic Acid Activates Notch-1 Signaling and Induces Apoptosis in Medullary Thyroid Carcinoma Cells

(2008) L. Ning et al.   ONCOLOGIST

Unique Properties of DNA Interstrand Cross-Links of Antitumor Oxaliplatin and the Effect of Chirality of the Carrier Ligand

(2007) Jana Kasparkova et al.   CHEMISTRY-A EUROPEAN JOURNAL