Bacterial E3 Ubiquitin Ligase IpaH4.5 ofShigella flexneriTargets TBK1 To Dampen the Host Antibacterial Response

Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer

(2014) Congwen Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shigella flexneriT3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein

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IRF3: a molecular switch in pathogen responses

(2012) Osamu Takeuchi   NATURE IMMUNOLOGY

Avian influenza virus H5N1 induces rapid interferon-beta production but shows more potent inhibition to retinoic acid-inducible gene I expression than H1N1 in vitro

(2012) Zhiqiang Mi et al.   Virology Journal

Opposing Roles for Interferon Regulatory Factor-3 (IRF-3) and Type I Interferon Signaling during Plague

(2012) Ami A. Patel et al.   PLoS Pathogens

Functional Analysis of NopM, a Novel E3 Ubiquitin Ligase (NEL) Domain Effector of Rhizobium sp. Strain NGR234

(2012) Da-Wei Xin et al.   PLoS Pathogens

K63-Linked Ubiquitination in Kinase Activation and Cancer

(2012) Guocan Wang et al.   Frontiers in Oncology

STING is a direct innate immune sensor of cyclic di-GMP

(2011) Dara L. Burdette et al.   NATURE

Type I interferons in systemic autoimmunity

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The many faces of the YopM effector from plague causative bacterium Yersinia pestis and its implications for host immune modulation

(2010) Venkataramanan Soundararajan et al.   Innate Immunity

Type I Interferon Induction Is Detrimental during Infection with the Whipple's Disease Bacterium, Tropheryma whipplei

(2010) Khatoun Al Moussawi et al.   PLoS Pathogens

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

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A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response

(2009) Hiroshi Ashida et al.   NATURE CELL BIOLOGY

NDP52: the missing link between ubiquitinated bacteria and autophagy

(2009) Stanimir Ivanov et al.   NATURE IMMUNOLOGY

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Interferon Protects Mice Against Inhalation Anthrax

(2008) Kristin Walberg et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Structure of a Shigella effector reveals a new class of ubiquitin ligases

(2008) Yongqun Zhu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

(2008) Alexander U Singer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?

(2008) Tieu-Lan Chau et al.   TRENDS IN BIOCHEMICAL SCIENCES