Cutting Edge: Plasmacytoid Dendritic Cells in Late-Stage Lupus Mice Defective in Producing IFN-α

Paradoxical Effects of All-Trans-Retinoic Acid on Lupus-Like Disease in the MRL/lpr Mouse Model

(2015) Xiaofeng Liao et al.   PLoS One

Advances in understanding the role of type I interferons in systemic lupus erythematosus

(2014) Mary K. Crow   CURRENT OPINION IN RHEUMATOLOGY

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

(2014) Sarah L. Rowland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus

(2014) Vanja Sisirak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I Interferon in the Pathogenesis of Lupus

(2014) M. K. Crow   JOURNAL OF IMMUNOLOGY

Sifalimumab, a Human Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus: A Phase I Randomized, Controlled, Dose-Escalation Study

(2013) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Anti-interferon alpha treatment in SLE

(2013) Kyriakos A. Kirou et al.   CLINICAL IMMUNOLOGY

Sca-1 expression defines developmental stages of mouse pDCs that show functional heterogeneity in the endosomal but not lysosomal TLR9 response

(2013) Marina Niederquell et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Exacerbated Autoimmunity in the Absence of TLR9 in MRL.Faslpr Mice Depends on Ifnar1

(2013) K. M. Nickerson et al.   JOURNAL OF IMMUNOLOGY

Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study

(2012) Jacqueline M. McBride et al.   ARTHRITIS AND RHEUMATISM

Type I IFN system in the development and manifestations of SLE

(2012) Keith B. Elkon et al.   CURRENT OPINION IN RHEUMATOLOGY

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Myeloid Dendritic Cells from B6.NZM Sle1/Sle2/Sle3 Lupus-Prone Mice Express an IFN Signature That Precedes Disease Onset

(2012) U. Sriram et al.   JOURNAL OF IMMUNOLOGY

TLR Tolerance Reduces IFN-Alpha Production Despite Plasmacytoid Dendritic Cell Expansion and Anti-Nuclear Antibodies in NZB Bicongenic Mice

(2012) Evelyn Pau et al.   PLoS One

Safety profile and clinical activity of sifalimumab, a fully human anti-interferon   monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

(2011) J. T. Merrill et al.   ANNALS OF THE RHEUMATIC DISEASES

Type I Interferon and Systemic Lupus Erythematosus

(2011) Keith B. Elkon et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

(2010) A. L. Blasius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus

(2010) Ou Jin et al.   ARTHRITIS RESEARCH & THERAPY

Neutralization of interferon-α/β-inducible genes and downstream effect in a phase I trial of an anti-interferon-α monoclonal antibody in systemic lupus erythematosus

(2009) Yihong Yao et al.   ARTHRITIS AND RHEUMATISM

Deficiency of Type I IFN Receptor in Lupus-Prone New Zealand Mixed 2328 Mice Decreases Dendritic Cell Numbers and Activation and Protects from Disease

(2009) H. Agrawal et al.   JOURNAL OF IMMUNOLOGY