Article
Fisheries
Qinglin Yang, Xiaobo Yu, Chunying Du, Xin Ni, Wenyu Li, Weizhi Yao, Zhengli Wu
Summary: This study evaluated the effects of common pathogenic infections on immune function in the bivalve species Hyriopsis cumingii. The results showed that infection with different pathogens led to changes in antioxidant enzyme activities and histological alterations. Bacterial infection increased total haemocyte counts and especially the proportion of granulocytes in H. cumingii.
Review
Endocrinology & Metabolism
Jennifer S. Stancill, John A. Corbett
Summary: Oxidative stress is implicated in pancreatic beta-cell damage in type 1 and type 2 diabetes, potentially leading to dysfunction and death of beta cells. Beta cells are vulnerable to oxidative damage but have high expression of antioxidant enzymes which may help maintain their function and survival.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Patricia P. Adriani, Fernanda C. R. de Paiva, Gabriel S. de Oliveira, Amanda C. Leite, Adriana S. Sanches, Adriana Rios Lopes, Marcio V. B. Dias, Felipe S. Chambergo
Summary: The study characterized the functional and structural features of a glutathione peroxidase (GPx) identified in Trichoderma reesei, demonstrating that TrGPx is a thioredoxin peroxidase with better hydrolysis activity towards H2O2 than t-BOOH. Additionally, TrGPx showed optimal pH range and half-life at 80 degrees Celsius.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Biochemistry & Molecular Biology
Hirofumi Kiyokawa, Yuma Hoshino, Kazuhiro Sakaguchi, Shigeo Muro, Junji Yodoi
Summary: Epithelial cells in the respiratory system are directly exposed to exogenous ROS, increasing the risk of oxidative stress; Dysfunction of redox regulation due to cellular aging accelerates COPD pathogenesis; Drugs targeting oxidative stress pathways can help precisely regulate the redox system.
Review
Pharmacology & Pharmacy
Sicong Wang, Giovanna Di Trapani, Kathryn F. Tonissen
Summary: This review discusses the upregulation of Nrf-2 regulated antioxidant systems in lymphomas and their association with multiple signaling pathways involved in lymphoma development and progression. Targeting antioxidant systems, especially TrxR, may represent a new therapeutic approach for lymphoma.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Fisheries
Heloise Gendre, Yosra Ben Cheikh, Frank Le Foll, Alain Geffard, Melissa Palos Ladeiro
Summary: This study compared the sensitivity of cellular immunomarkers to chemical stressors combined with bacterial challenge in two mussel species from different environments. The results showed that the two mussel species had different basal levels and responded differently to chemical exposure and bacterial challenge. This work highlights the species-specific sensitivity of mussel immunomarkers to contaminants and the necessity of considering the presence of non-pathogenic microorganisms in future in situ applications.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Atsuki Shimizu, Ryuta Tobe, Riku Aono, Masao Inoue, Satoru Hagita, Kaito Kiriyama, Yosuke Toyotake, Takuya Ogawa, Tatsuo Kurihara, Kei Goto, N. Tejo Prakash, Hisaaki Mihara
Summary: The study revealed that the thioredoxin system from Pseudomonas stutzeri specifically reduces selenite in the presence of TrxA (PsTrxA), with Cys33 and Cys36 residues being crucial for selenite reduction via the formation of PsTrxA-SeO intermediate. The results also suggest the importance of TrxA in selenoprotein biosynthesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Composites
Heliang Wang, Xiwei Guo, Yu Liu, Mingyuan Yi, Lihong Wan, Shuangquan Liao, Zhifen Wang, Lin Fang
Summary: The study synthesized eco-friendly polydopamine-loaded silica particles and added them to natural rubber, improving the mechanical performance and interfacial interaction of the composite material.
COMPOSITES COMMUNICATIONS
(2022)
Article
Biophysics
Shiyu Wang, Ruiqi Liu, Siwei Bi, Xueshan Zhao, Guixiang Zeng, Xiaoyi Li, Haibo Wang, Jun Gu
Summary: In this study, a highly adhesive zwitterionic composite hydrogel wound dressing with outstanding antibacterial properties, good biocompatibility, and excellent rheological properties was prepared. The composite hydrogel showed broad-spectrum and lasting antibacterial activity against Escherichia coli and Staphylococcus aureus in vitro and in vivo experiments.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Agriculture, Dairy & Animal Science
Walid S. Habashy, Marie C. Milfort, Romdhane Rekaya, Samuel E. Aggrey
Summary: Performance traits and mortality of chickens are negatively impacted by heat stress, with the thioredoxin pathway system potentially offering clues for nutritional strategies to mitigate these effects.
Article
Materials Science, Multidisciplinary
Mingjun Li, Christoph Schlaich, Jianguang Zhang, Ievgen S. Donskyi, Karin Schwibbert, Frank Schreiber, Yi Xia, Jorg Radnik, Tanja Schwerdtle, Rainer Haag
Summary: This study successfully introduced antibacterial and osteogenic properties simultaneously in biomaterials by incorporating copper nanoparticles into a PCL membrane, leading to effective bactericidal activity against S. aureus, E. coli, and multidrug-resistant E. coli, as well as upregulation of osteoblast-related gene expressions and protein activity.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Izabela Sadowska-Bartosz, Grzegorz Bartosz
Summary: Peroxiredoxin 2 (Prdx2) is an abundant erythrocyte protein that acts as an antioxidant, removing hydrogen peroxide and other peroxides. It can also serve as a chaperone for hemoglobin and erythrocyte membrane proteins.
Article
Fisheries
Fernanda Silva dos Santos, Raquel A. F. Neves, Benoit Bernay, Natascha Krepsky, Valeria Laneuville Teixeira, Sebastien Artigaud
Summary: In this study, the protein profile of the hepatopancreas of Perna perna mussel challenged by Escherichia coli, Salmonella enterica, and Vibrio parahaemolyticus was investigated. The results showed that these bacteria induced significant changes in the expression levels of immune-related proteins in the mussel. This study provides valuable insights into the immune-bacteria relationship in mussels.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Bo Wang, Peipei Zhang, Qianqian Wang, Shuaijun Zou, Juxingsi Song, Fuhai Zhang, Guoyan Liu, Liming Zhang
Summary: This study confirms that the fusion protein PTD-CcTrx1 obtained from the jellyfish Cyanea capillata has antioxidant abilities and can protect skin cells from oxidative damage. The findings provide critical evidence for the future application of PTD-CcTrx1 as a treatment for skin oxidative damage.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Microbiology
Yan Sun, Minxiao Wang, Lei Cao, Inge Seim, Li Zhou, Jianwei Chen, Hao Wang, Zhaoshan Zhong, Hao Chen, Lulu Fu, Mengna Li, Chaolun Li, Song Sun
Summary: This study conducted a fine-scale metagenomic analysis of the deep-sea mussel Gigantidas platifrons bacterial endosymbiont collected from distinct habitats, and revealed the important role of within-species diversity in symbiotic bacteria's environmental adaptation. The study also uncovered the environment-driven evolution of deep-sea symbionts mediated by mobile genetic elements.
Article
Environmental Sciences
Qing Wang, Jinjun Li, Xiaopeng Zhu, Chaofan Sun, Jia Teng, Limei Chen, Encui Shan, Jianmin Zhao
Summary: The study found widespread microplastic pollution in fish meal samples from ten countries, with higher levels in China, Peru, and Myanmar. The average amount of microplastics in fish meals was 5.5 items/gram, predominantly in fiber form and sized between 500-1000 micrometers.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Xin Wang, Tianyu Zhang, Qianqian Zhang, Rui Xue, Yi Qu, Qing Wang, Zhijun Dong, Jianmin Zhao
Summary: Hypoxia caused by human activities and global climate change has a significant impact on marine ecosystems. The influence of nanoplastics on marine organisms has attracted attention, but the impact of hypoxia on nanoplastic risk assessments is often overlooked. This study found that constant hypoxia reduces the accumulation of nanoplastics in mussels by decreasing metabolic rate, while fluctuating hypoxia exacerbates the oxidative damage caused by nanoplastics.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Liang Chen, Xiutang Yuan, Yuheng Ye, Jia Teng, Jianmin Zhao, Qing Wang, Bin Zhang
Summary: This study analyzed the abundance, characteristics, spatiotemporal distribution, and pollution risk of microplastics in the sediments of mariculture ponds and offshore areas in Qingduizi Bay. The results showed that the microplastics were mainly composed of polyethylene terephthalate (PET) and cellophane (CP), and the pollution load index (PLI) assessment indicated that all sampling sites were at Hazard Level I. This study provides valuable information for the risk assessment of microplastic pollution in mariculture areas.
MARINE POLLUTION BULLETIN
(2022)
Article
Environmental Sciences
Tianyu Zhang, Xin Wang, Yi Qu, Xiaoli Zhang, Qianqian Zhang, Dinglong Yang, Qing Wang, Zhijun Dong, Jianmin Zhao
Summary: Ocean acidification (OA) and antibiotic pollution can cause significant disruptions to the intestinal microbiota of the herbivorous gastropod Trochus niloticus, a keystone species in coral reef ecosystems. OA exposure leads to dysbiosis in the intestinal microbiota, while environmentally relevant concentrations of sulfamethoxazole (SMX) have minimal impact. However, higher concentrations of SMX induce an increase in the copies of sulfonamide resistance genes in the intestinal microbiota. These findings highlight the potential adverse effects of OA and antibiotic pollution on the intestinal health and fitness of T. niloticus.
Article
Environmental Sciences
Xin Wang, Qianqian Zhang, Tianyu Zhang, Shengyuan Shao, Qing Wang, Zhijun Dong, Jianmin Zhao
Summary: In this study, the impact of polystyrene nanospheres (PS-NPs) on the digestive performance of mussels under different hypoxia patterns was investigated. It was found that PS-NPs caused oxidative damage in the digestive glands of mussels, and the hypoxia patterns exacerbated this damage. The activities of four digestive enzymes were examined, and it was observed that PS-NPs inhibited alpha-amylase activity, enhanced cellulase and trypsin activity, and had no effect on lipase activity alone but showed significant inhibition when combined with hypoxia. Overall, this research provides new insights into the ecological risk assessment of plastics under the influence of global climate change.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Yuheng Ye, Anguo Zhang, Jia Teng, Xiaolong Yang, Xiutang Yuan, Qing Wang, Jianmin Zhao, Bin Zhang, Tianzhe Zhang, Xuejiao Chen, Tongwei Guan, Xindong Ma
Summary: This study investigated the pollution characteristics of microplastics (MPs) in surface sediments of the Liao Estuary and Daliao Estuary. The MPs were mainly composed of black and blue fibers with sizes ranging from 500 to 2000 µm. Five polymer types were identified, and the risk assessment showed that all sampling sites were at Hazard Level I. These findings provide useful information for assessing the environmental risks of MPs in coastal areas of China.
MARINE POLLUTION BULLETIN
(2023)
Article
Environmental Sciences
Jia Teng, Jianmin Zhao, Chaofan Sun, Encui Shan, Minxiao Wang, Qing Wang
Summary: Research found that deep-sea organisms in the South China Sea, including Gigantidas platifrons and Shinkaia crosnieri, have ingested microplastic pollution at rates of 80.98% and 81.25% respectively. These microplastics are predominantly fibrous, blue in color, and sized 500-1000 μm, composed of polyethylene terephthalate and cellophane. The study provides further evidence of microplastic pollution in the deep sea.
MARINE POLLUTION BULLETIN
(2023)
Article
Chemistry, Analytical
Wei Zhang, Weiwei Feng, Zongqi Cai, Huanqing Wang, Qi Yan, Qing Wang
Summary: This paper proposes a method using Raman spectroscopy combined with a one-dimensional convolutional neural network (1D-CNN) to accurately identify microplastics. The experimental results show that this method achieves the highest accuracies of 96.4% and 96.2% based on raw data and pre-processed data, respectively. Compared with K-Nearest Neighbors (KNN), Support Vector Machine (SVM), Multi-layer Perceptron (MLP), and AlexNet classifiers, the proposed method has an average accuracy of 95.8% and 95.5% on raw data and pre-processed data, respectively. This study proves that Raman spectroscopy combined with 1D-CNN can effectively and accurately classify microplastics, regardless of whether the spectra data are pre-processed or not, and can further shorten the recognition time, providing a reference for future microplastics detection.
VIBRATIONAL SPECTROSCOPY
(2023)
Article
Marine & Freshwater Biology
Ye Zhao, Han Wang, Haona Wang, Hui Liu, Yanying Zhang, Jianwei Zhang, Yongrui Pi, Pei Yang, Qing Wang
Summary: This study investigated the toxic response in the intestine of juvenile A. japonicus under sulfide stress. The results showed sulfide-induced intestinal inflammation and oxidative stress, as well as changes in gut bacterial composition and metabolic homeostasis. Interestingly, certain intestinal bacteria were found to be significantly correlated with metabolic changes. These findings provide new insights into the adaptation strategies of juvenile A. japonicus under sulfide stress.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Chaofan Sun, Jia Teng, Dongyu Wang, Jianmin Zhao, Encui Shan, Qing Wang
Summary: Microplastics in marine environments can be attached by various microorganisms, including pathogenic bacteria, which can enter the bodies of bivalves when they mistakenly eat these microplastics. This study examined the synergistic effect of exposure to aged polymethylmethacrylate microplastics and Vibrio parahaemolyticus in mussels. The results showed that coexposure to microplastics and bacteria significantly inhibited antioxidant enzyme activities in the gills of mussels, and induced higher levels of reactive oxygen species (ROS), improved phagocytosis, reduced lysosomal membrane stability, and increased expression of apoptosis-related genes in hemocytes compared to single microplastic exposure.
Article
Environmental Sciences
Shuhao Xu, Weijun Wang, Bingqing Xu, Xin He, Zhixu Chen, Xiaoran Zhao, Yifei Zhang, Shuyu Zhou, Yan Fang, Qing Wang
Summary: This study investigated the effects of environmentally relevant concentrations of the progestin norgestrel (NGT) on the sperm of Pacific oysters. The results showed that NGT had a positive effect on sperm motility, but also caused oxidative stress and decreased fertilization rates. However, hatching rates were not significantly affected.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Xiaodan Wang, Xiaoli Zhang, Cheng Yao, Encui Shan, Xiaojing Lv, Jia Teng, Jianmin Zhao, Qing Wang
Summary: This study investigates the effects of aged microplastics (MPs) on estuarine nitrogen cycling and microbial ecosystems. The results show that aged MPs have a greater and faster impact on sediment nitrogen turnover compared to virgin MPs. In addition, the aged MPs significantly affected N2O emission and microbial community composition.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Environmental Sciences
Jiasen Li, Encui Shan, Jianmin Zhao, Jia Teng, Qing Wang
Summary: There have been numerous studies on the presence of low-density microplastics (MPs) in water and sediments. Current research focuses on the interaction of MPs with marine organisms and their potential hazards. This review summarizes the current knowledge on the vertical transport of MPs influenced by their physicochemical properties and marine organisms, and discusses their potential impact on MPs deposition.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Haona Wang, Hui Liu, Yanying Zhang, Lijie Zhang, Qing Wang, Ye Zhao
Summary: Microplastic pollution poses a major threat to marine biota, with both direct exposure to microplastics and leachates from them being toxic. The leachates of PVC microspheres were found to have higher toxicity on sea cucumber embryo development and larval growth, and the presence of phthalate esters in the leachates may contribute to their increased toxicity.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Proceedings Paper
Optics
Zong-Qi Cai, Wei-Wei Feng, Huan-Qing Wang, Xing-Hui Lang, Jian-Lian Yang, Xue Wu, Qing Wang
Summary: The combination of spectroscopic technology and machine learning algorithm provides technical support for the rapid identification of microplastics. Raman and infrared spectroscopy can complement each other, and a high-speed and effective recognition and classification model was built using Random Forest, Extreme Gradient Boosting, and Artificial Neural Network algorithms. The performance evaluation shows that the random forest model has the highest recognition accuracy.
OPTICAL DESIGN AND TESTING XII
(2023)