Article
Biochemistry & Molecular Biology
Zesheng Hao, Bin Yu, Wei Gao, Haoyin Chen, Dongyan Yang, You Lv, Yue Zhang, Lei Chen, Zhijin Fan
Summary: Twenty-one novel pyrazole-thiazole carboxamide derivatives were synthesized and evaluated for their fungicidal activities, with compounds 6d and 6j showing promising results both in vitro and in vivo, particularly compound 6j demonstrating good protective activity against Rhizoctonia solani and Puccinia sorghi Schw.
MOLECULAR DIVERSITY
(2022)
Article
Chemistry, Physical
Sraa Abu-Melha
Summary: The thiadiazole-pyrazole hybrid 3 was synthesized and used to produce four thiadiazole-pyrazole compounds 5 and 6a-c. The configuration and energetic properties of the hybrids were studied, revealing a small energy gap and a specific sorting order. The synthesized thiadiazole-pyrazole hybrids exhibited significant antitumor activities and binding appropriateness with caspase-3 enzyme.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Agriculture, Multidisciplinary
Liang-Kun Zhong, Xin-Peng Sun, Liang Han, Cheng-Xia Tan, Jian-Quan Weng, Tian-Ming Xu, Jian-Jun Shi, Xing-Hai Liu
Summary: This study focused on the design and synthesis of a series of novel insecticides. One compound, IA-8, showed excellent insecticidal activity against M. separate, comparable to the positive control fluralaner. Molecular docking results demonstrated that IA-8 and fluralaner have a similar binding mode to the GABA active site. This work provides a promising starting point for further optimization of insecticides.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agronomy
Dongdong Liu, Jing Zhang, Yixing Gao, Haijing Hao, Chenyang Zhang, Feng Wang, Lixin Zhang
Summary: Compound 25b, a novel phenyl trifluoroethyl thioether compound containing a substituted benzyl group, exhibits excellent acaricidal activity against Tetranychus cinnabarinus. Its control effect on mites is more facile and long-lasting compared to the commercial acaricide spirodiclofen.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agricultural Engineering
Xijie Shan, Min Lv, Jingru Wang, Yujia Qin, Hui Xu
Summary: New osthole esters containing the isoxazoline fragment were constructed by modifying a natural coumarin osthole, and their agricultural activities against two pests were evaluated. Some compounds showed high insecticidal and acaricidal activities, and the introduction of the acryloyloxy group was found to be important for activity.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Physical
Andres Restrepo-Acevedo, Nicolas Osorio, Luis E. Giraldo-Lopez, Richard F. D'Vries, Susana Zacchino, Rodrigo Abonia, Ronan Le Lagadec, Fernando Cuenu-Cabezas
Summary: In this study, three new pyrazole-based azomethine isomers were synthesized using environmentally friendly techniques. The addition of a nitrophenyl group on the pyrazole moiety was found to tune the band gap energy and reactivity, leading to increased antifungal activity against C. albicans for the compound bearing the 2-nitrophenyl substituent. Molecular docking simulations also confirmed the strong binding affinity of the most active compound with a model protein.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Physical
Sana Saffour, Amal A. AL-Sharabi, Asaf Evrim Evren, Meral Yilmaz Cankilic, Leyla Yurttas
Summary: In this study, thirteen new compounds were synthesized and evaluated for their antifungal and antimicrobial activities. One compound exhibited the best activity and selectivity against Yersinia enterocolitica. Additionally, all compounds showed good activity against filamentous fungi.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Agronomy
Xing-Jie Peng, Xue-Rong Tian, Shu-Jing Yu, Tong-Tong Zhao, Qiang Bian, Wei-Guang Zhao
Summary: This study designed and synthesized a series of piperazine thiazole derivatives containing oxime ether or oxime ester moieties and investigated their fungicidal activities. The results showed that these derivatives exhibited moderate to good fungicidal activities against Phytophthora capsici, with two oxime ether derivatives showing higher activity than dimethomorph and comparable to oxathiapiprolin. Oxime ester derivatives showed reduced activities. Most of these derivatives showed broad-spectrum fungicidal activity against other fungi, and four derivatives showed good antifungal activities against various pathogens. Compound 10d might cause mycelial abnormalities of Phytophthora capsici.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agriculture, Multidisciplinary
Ling Jia, Shuang Gao, Yuan-Yuan Zhang, Li-Xia Zhao, Ying Fu, Fei Ye
Summary: The article presents a novel pyrazole derivative that successfully reduces the phytotoxicity of fenoxaprop-p-ethyl to wheat while maintaining effectiveness on target weed species, demonstrating potential for application in protecting wheat from herbicide injury.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Medicinal
Chungsik Kim, Mintesinot Kassu, Kenneth P. Smith, James E. Kirby, Roman Manetsch
Summary: A total of 20 novel derivatives of compound KP-40 containing Pyrazole-thiazole core were designed and synthesized through traditional SAR analysis. Four of the compounds showed significant adjunctive potential with improved solubility, and key physicochemical properties for the development of active Gram-negative antibacterials were revealed through further analysis using PEMPO algorithm. Consideration of PEMPO scores prior to synthesis of analogs may be a simple yet effective strategy in conjunction with traditional SAR approaches for designing potent Gram-negative antibacterials.
Article
Agriculture, Multidisciplinary
Shilin Chen, Yu Zhang, Yuxiu Liu, Qingmin Wang
Summary: In this study, a series of novel 2,4-diphenyl-1,3-oxazolines bearing various N-heterocyclic substituents were designed and synthesized, showing good larvicidal and ovicidal activities, which is significant for the development of acaricides.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Agriculture, Multidisciplinary
Dongguo Xia, Xiang Cheng, Xiaohang Liu, Chengqi Zhang, Yunxiao Wang, Qiaoyun Liu, Qi Zeng, Niqian Huang, Yao Cheng, Xianhai Lv
Summary: Novel pyrazole carboxylate derivatives containing a flexible thiazole backbone were successfully synthesized and evaluated for their antifungal bioactivities. Compound 24 showed excellent bioactivities against Botrytis cinerea and Sclerotinia sclerotiorum, while compound 15 exhibited remarkable antifungal activity against Valsa mali. Compounds 3, 15, and 24 are promising antifungal candidates worthy of further fungicide development.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Agriculture, Multidisciplinary
Zhenwu Yu, Xiulan Zhang, Jinzhou Ren, Haolin Yuan, Wei Gao, Lixia Xiong, Na Yang, Yuxin Li, Zhengming Li, Zhijin Fan
Summary: In this study, a series of anthranilic diamide compounds were designed and synthesized for their insecticidal activity. These compounds showed good toxicity against several insect species, including some that were more active than the commonly used chlorantraniliprole. Molecular docking and calcium imaging experiments provided evidence for the potential target of these compounds as RyRs. The results suggest that these compounds could be promising leads for the development of more effective insecticides.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Agronomy
Shuai Yang, Jiahong Tang, Hongxiang Peng, Chunmei Pu, Shuting Fan, Chen Zhao, Hanhong Xu
Summary: Agricultural pests cause significant damage to crop production and pose a threat to global food security. Developing efficient insecticides with novel structures is urgently needed due to the rapid development of pest resistance and strict pesticide regulations.
PEST MANAGEMENT SCIENCE
(2023)
Article
Chemistry, Physical
Alia Abdulaziz Alfi, Arwa Alharbi, Jihan Qurban, Matokah M. Abualnaja, Hana M. Abumelha, Fawaz A. Saad, Nashwa M. El-Metwaly
Summary: In this study, the phenoxyacetamide moiety was used as a link bridge for the synthesis of novel pyrazole-integrated thiazole derivatives. The synthesized compounds were subjected to geometric optimization and activity evaluation using computational methods.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Biochemical Research Methods
Quanjuan Zhang, Na Zhang, Yi-Tao Long, Xuhong Qian, Youjun Yang
BIOCONJUGATE CHEMISTRY
(2016)
Article
Chemistry, Analytical
Ziqian Zhang, Jiayao Wu, Zhihao Shang, Chao Wang, Jiagao Cheng, Xuhong Qian, Yi Xiao, Zhiping Xu, Youjun Yang
ANALYTICAL CHEMISTRY
(2016)
Article
Medicine, Research & Experimental
Kecheng Lei, Wenpei Du, Shengchao Lin, Liyan Yang, Yichun Xu, Yuwei Gao, Baixue Xu, Shaoying Tan, Yufang Xu, Xuhong Qian, Xin Liang, Jianwen Liu
BIOMEDICINE & PHARMACOTHERAPY
(2016)
Article
Chemistry, Multidisciplinary
Lei Zhang, Jun Yuan, Yufang Xu, Y. -H. Percival Zhang, Xuhong Qian
CHEMICAL COMMUNICATIONS
(2016)
Article
Chemistry, Inorganic & Nuclear
Junhua Jia, Luling Wu, Yu Ding, Chusen Huang, Weiping Zhu, Yufang Xu, Xuhong Qian
DALTON TRANSACTIONS
(2016)
Article
Chemistry, Applied
Tanyu Cheng, Junwei Zhao, Ziyun Wang, Juzeng An, Yufang Xu, Xuhong Qian, Guohua Liu
Article
Pharmacology & Pharmacy
Yujie Li, Mingyang Hei, Yufang Xu, Xuhong Qian, Weiping Zhu
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2016)
Article
Chemistry, Physical
Yao Tang, Yu Liu, Yiqiao Qin, Yufang Xu, Xuhong Qian, Weiping Zhu
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2016)
Article
Chemistry, Multidisciplinary
Mengfang Tang, Luling Wu, Dan Wu, Chusen Huang, Weiping Zhu, Yufang Xu, Xuhong Qian
Article
Chemistry, Multidisciplinary
Qi Cai, Gaosheng Liang, Yufang Xu, Xuhong Qian, Weiping Zhu
Article
Multidisciplinary Sciences
Kang Chang, Tongtong Guo, Pengfei Li, Yin Liu, Yufang Xu, Yuda Fang, Xuhong Qian
SCIENTIFIC REPORTS
(2016)
Article
Chemistry, Multidisciplinary
Mingwei Zhou, Ke En, Yimin Hu, Yufang Xu, Hong C. Shen, Xuhong Qian
Article
Chemistry, Multidisciplinary
Kang Chang, Jian-Qin Chen, Yan-Xia Shi, Mei-Jian Sun, Peng-Fei Li, Zhen-Jiang Zhao, Wei-Ping Zhu, Hong-Lin Li, Yu-Fang Xu, Bao-Ju Li, Xu-Hong Qian
CHINESE CHEMICAL LETTERS
(2017)
Article
Chemistry, Multidisciplinary
Zuhai Lei, Xinran Li, Xiao Luo, Haihong He, Jing Zheng, Xuhong Qian, Youjun Yang
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2017)
Article
Chemistry, Applied
Dandan Li, Yuqiong Xu, Nannan Zhou, Jianxu Liu, Rui Wang, Tao Cheng, Yun Tang, Weiping Zhu, Yufang Xu, Xuhong Qian
Article
Chemistry, Multidisciplinary
Qian Wu, Yubo Cui, Guifeng Xia, Jinlong Yang, Shuming Du, Xinhong Xiong, Li Yang, Dong Xu, Xu Deng, Jiaxi Cui
Summary: Passive daytime radiative cooling (PDRC) technology, while promising for global spacing cooling, faces limitations in practical application due to reduced cooling effectiveness caused by wear and dirt contamination. Researchers have developed a renewable armor structure using fluorinated hollow glass microspheres to enhance the anti-fouling and cooling properties of PDRC coatings. The coatings exhibit high solar reflectance and thermal emittance, leading to significant temperature reduction below ambient temperature.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qiang Bei, Bei Zhang, Kaifeng Wang, Shiming Zhang, Guichuan Xing, Clement Cabanetos
Summary: The power conversion efficiency (PCE) of organic solar cells (OSCs) has reached 20% in recent years, thanks to the advantages of organic photoactive materials. Benzothiadiazole (BT) has attracted significant research attention as a building block of OSCs. OSCs based on BT structure have shown diversity, and the increasing PCE values indicate a promising future for OSCs. This review analyzes the progress made in the last decades, focusing on effective BT small-molecules and BT polymers for OSCs. The structure-property relationships, donor-acceptor matching criteria, and morphology control approaches are discussed. The remaining challenges and a personal perspective on the future advancement of OSCs are summarized.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Rong He, Dandan Tang, Ningge Xu, Heng Liu, Kun Dou, Xuejun Zhou, Fabiao Yu
Summary: Nasopharyngeal carcinoma (NPC) is a common malignant tumor of the head and neck, with a high incidence in China and Southeast Asian countries. In this study, a novel near-infrared fluorescent probe, SNAFL-GSH, was designed and synthesized for the detection of glutathione (GSH). The probe showed selective detection of GSH and the ability to distinguish normal and cancer cells. It has great potential for application in the diagnosis and evaluation of NPC.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhongshan Yang, Qiqi Zhang, Hui Song, Xin Chen, Jiwei Cui, Yanhui Sun, Lequan Liu, Jinhua Ye
Summary: Methane chemistry is a significant area of research in catalysis. Converting methane into value-added chemicals is desirable but challenging due to its high C-H bonding energy and lack of pi bonding or unpaired electrons. Photocatalytic partial oxidation of methane to liquid oxygenates is a promising technology for achieving high efficiency and selectivity under mild conditions. The choice and activation of oxidants are crucial for its performance.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Peng Shan, Jing Liao, Jiayi Li, Chengyan Wang, Jie Zhou, Linqiang Mei, Yunlu Dai, Qiang Wang, Wenyan Yin
Summary: This study reports an oral radioprotectant Gel@GYY that combines a gelatin-based hydrogel and a pH-responsive hydrogen sulfide donor. Gel@GYY has excellent adhesion and sustained release properties, allowing it to release H2S in the gastrointestinal tract and effectively scavenge free radicals induced by radiation. It also reduces inflammation and has biodegradable properties.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lu Liu, Ziyi Liu, Jingnan Cui, Guiling Ning, Weitao Gong
Summary: The development of new metal-free heterogeneous catalysts has been the subject of extensive research. In this study, a new Troger's base (TB)-derived porous organic polymer (POPs) was designed and prepared by integrating multifunctional monomers. The resulting polymer, which combines the advantages of pillar[5]arene macrocycle and TB moiety, exhibited enhanced catalytic performance in Knoevenagel condensation and CO2 conversion, serving as an effective metal-free catalyst. This work provides a new strategy for fabricating metal-free heterogeneous catalysts based on macrocyclic POPs.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Haihong Lai, Zehong Chen, Hao Zhuo, Yijie Hu, Xuan Zhao, Jiwang Yi, Hongzhi Zheng, Ge Shi, Yifan Tong, Ling Meng, Xinwen Peng, Linxin Zhong
Summary: By altering the pyrolysis route of cellulose nanofiber, the structural defects of carbon aerogels can be reduced, leading to improved compressibility and stress retention, as well as higher stress sensor sensitivity and temperature coefficient.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lina Guo, Jinsong Ding, Wenhu Zhou
Summary: Bacteria-based tumor therapy has resurfaced due to the revolution of tumor immunotherapy, offering unique solutions for traditional tumor treatments. Bacteria with active tropism can selectively colonize tumor sites and suppress tumor growth through various mechanisms, making them attractive tools for tumor treatment. This critical review introduces recent advances in bacteria-based tumor therapy, including bacterial properties, their benefits for tumor therapy, anti-tumor mechanisms, challenges, and future perspectives.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lan Liang, Chuanbin Wang, Xukai Lu, Yunan Sun, Beibei Yan, Ning Li, Guanyi Chen, Li'an Hou
Summary: This study investigates the interactions between phenol and benzaldehyde in the ECH process through experiments and theoretical calculations. The results show that phenol can accelerate the conversion of benzaldehyde, while benzaldehyde inhibits the conversion of phenol. The research provides a theoretical basis for the application of ECH in practical bio-oil upgrading.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Pengcheng Fan, Yuhao He, Junan Pan, Ning Sun, Qiyu Zhang, Chen Gu, Kang Chen, Weinan Yin, Longlu Wang
Summary: This study focuses on the recent progress in hydrogen evolution reaction (HER) based on photothermal effect. It introduces the main pathways of photothermal conversions applied in H2 evolution, summarizes the functions of the photothermal effect, and presents a method to improve the catalytic system through thermal means. The study also discusses the challenges and outlook in this promising area.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leiduo Lai, Hongyu Zhou, Yichen Hong, Mengfan Luo, Yang Shi, Heng Zhang, Zhaokun Xiong, Gang Yao, Bo Lai
Summary: In this study, a facile ammonia reduction strategy was proposed and a novel FeVO3-x catalyst was synthesized for the activation of peroxymonosulfate (PMS) to degrade the pharmaceutical carbamazepine (CBZ). The results showed that the system could rapidly degrade CBZ and generate various active species involved in the degradation process.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)
