Journal
CHIMIA
Volume 68, Issue 6, Pages 430-435Publisher
SWISS CHEMICAL SOC
DOI: 10.2533/chimia.2014.430
Keywords
Alkenes; Aminofluorination; Difunctionalization
Categories
Funding
- University of Zurich
- European Union through an ERC Starting Grant [307948]
Ask authors/readers for more resources
The aminofluorination of alkenes has become an attractive platform for the synthesis of beta-amino-fluorinated compounds, valuable building blocks in medicinal and agricultural chemistry. The novel methodologies disclosed in recent years have unraveled a broad array of reaction mechanisms, so that the interest in these transformations transcends the mere synthetic aspects. This review aims to summarize the most relevant findings in this area attending at the nature of the fluorine source, and thus the specific mechanism operating in each of these transformations, namely electrophilic, nucleophilic, radical, and late transition metal-catalyzed reactions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available