Article
Clinical Neurology
S. Lee, S-K Kim, J. H. Phi
Summary: This study explored the feasibility of using the posterior auricular artery as an alternative donor artery for EDAS in pediatric patients with Moyamoya disease. Results showed that the postoperative outcomes of posterior auricular artery-EDAS were comparable to those of superficial temporal artery-EDAS, suggesting it as a viable option when the superficial temporal artery is unavailable.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2021)
Article
Critical Care Medicine
Lisa R. Sun, Lori C. Jordan, Edward R. Smith, Philipp R. Aldana, Matthew P. Kirschen, Kristin Guilliams, Nalin Gupta, Gary K. Steinberg, Christine Fox, Dana B. Harrar, Sarah Lee, Melissa G. Chung, Peter Dirks, Nomazulu Dlamini, Cormac O. Maher, Laura L. Lehman, Sue J. Hong, Jennifer M. Strahle, Jose A. Pineda, Lauren A. Beslow, Lindsey Rasmussen, Janette Mailo, Joseph Piatt, Shih-Shan Lang, P. David Adelson, Michael C. Dewan, Aleksandra Mineyko, Samuel McClugage, Sudhakar Vadivelu, Michael M. Dowling, David S. Hersh
Summary: The researchers used a modified Delphi process to establish expert consensus on perioperative care for children undergoing indirect revascularization surgery for moyamoya arteriopathy. They identified areas of consensus, such as preadmission for high-risk patients and administration of intravenous isotonic fluids, as well as research priorities for future studies.
NEUROCRITICAL CARE
(2023)
Article
Pediatrics
Nathan Grant, J. Michael Taylor, Zach Plummer, Kasiani Myers, Thomas Burrow, Lori Luchtman-Jones, Anna Byars, Adrienne Hammill, Katie Wusick, Edward Smith, James Leach, Sudhakar Vadivelu
Summary: MPS I is a rare lysosomal storage disorder that can present with neurological symptoms such as stroke. Our case study illustrates the successful treatment of a MPS I patient with cerebral revascularization to prevent recurrent strokes and neurological events. Further studies are necessary to understand the underlying etiology of cerebrovascular arteriopathy in MPS I patients.
FRONTIERS IN PEDIATRICS
(2021)
Review
Clinical Neurology
Vincent N. Nguyen, Mustafa Motiwala, Turki Elarjani, Kenneth A. Moore, L. Erin Miller, Michael Barats, Nitin Goyal, Lucas Elijovich, Paul Klimo, Daniel A. Hoit, Adam S. Arthur, Jacques J. Morcos, Nickalus R. Khan
Summary: Based on a systematic review and meta-analysis of relevant studies, combined and direct bypass have significant benefits over indirect bypass in the treatment of late stroke and intracerebral hemorrhage in adult moyamoya disease patients. Indirect bypass also performs better in early intracerebral hemorrhage. These findings have important implications for bypass strategy selection.
Article
Clinical Neurology
Ephraim W. Church, Rabia Qaiser, Teresa E. Bell-Stephens, Mark G. Bigder, Eric K. Chow, Summer S. Han, Yasser Y. El-Sayed, Gary K. Steinberg
Summary: An in-depth study on Moyamoya disease (MMD) patients who underwent cerebral revascularization and later became pregnant showed low complication rates and no major strokes among post-bypass pregnant patients. The overall rate of obstetric complications was also low. Collaborative efforts between vascular neurosurgeons and obstetricians are recommended for managing these patients effectively.
JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Anna L. Huguenard, Rejean M. Guerriero, Stuart R. Tomko, David D. Limbrick, Gregory J. Zipfel, Kristin P. Guilliams, Jennifer M. Strahle
Summary: Moyamoya disease and syndrome are progressive steno-occlusive cerebrovascular diseases that present with ischemic episodes. The use of EEG has been shown to be beneficial in the preoperative and intraoperative evaluation, but its potential usefulness in the immediate postoperative period for detecting early clinical and subclinical intracranial ischemia is proposed in this study.
PEDIATRIC NEUROLOGY
(2021)
Article
Clinical Neurology
Toshiaki Hayashi, Tomomi Kimiwada, Hiroshi Karibe, Reizo Shirane, Tatsuya Sasaki, Hirohito Metoki, Teiji Tominaga
Summary: In pediatric moyamoya disease, young age at diagnosis and a high MRA score may be associated with rapid disease progression and preoperative infarction. It is recommended that surgery be performed within 2 months of diagnosis for patients under 4 years of age with a high MRA score (>5) and cerebral infarction. Further study is needed to define the optimal timing of surgery.
Article
Clinical Neurology
Nathan A. Shlobin, H. Gregory Frankel, Sandi Lam
Summary: The literature indicates that factors such as disease cause, degree of moyamoya vessels, and surgical approach may influence the likelihood of Matsushima grade C revascularization in pediatric patients with MMD and MMS. Future research is needed to definitively determine factors associated with the failure of revascularization surgery for pediatric MMD.
WORLD NEUROSURGERY
(2021)
Review
Clinical Neurology
Nestor R. Gonzalez, Sepideh Amin-Hanjani, Oh Young Bang, Christopher Coffey, Rose Du, Jorn Fierstra, Justin F. Fraser, Satoshi Kuroda, Gretchen E. Tietjen, Shadi Yaghi
Summary: Adult moyamoya disease and syndrome are rare disorders with significant morbidity and mortality. This document provides an update on the current knowledge of these conditions, including definitions, diagnosis methods, and treatment options. However, there are still many unresolved questions and limitations in the field, requiring further research.
Article
Clinical Neurology
Jeyul Yang, Seung-Ki Kim, Min Kyung Chu, Young-Il Rho, Ji Hoon Phi, Seo-Young Lee
Summary: Headaches often persist or newly develop after revascularization surgery in patients with moyamoya disease (MMD). Accompanying nausea or vomiting and occurrence upon awakening are characteristic features.
CEREBROVASCULAR DISEASES
(2023)
Article
Oncology
Philipp R. Aldana, Ricardo A. Hanel, Joseph Piatt, Sabrina H. Han, Manisha M. Bansal, Corinna Schultz, Cynthia Gauger, John M. Pederson, John C. Wellons III, Monica L. Hulbert, Lori C. Jordan, Adnan Qureshi, Kelsey Garrity, Adam P. Robert, Asmaa Hatem, Jennifer Stein, Emily Beydler, P. David Adelson, Stephanie Greene, Paul Grabb, James Johnston, Shih-Shan Lang, Jeffrey Leonard, Suresh N. Magge, Alex Scott, Sanjay Shah, Edward R. Smith, Jodi Smith, Jennifer Strahle, Sudhakar Vadivelu, Jennifer Webb, David Wrubel
Summary: A multicenter retrospective study compared the occurrence and incidence rates of cerebrovascular events (CVEs) between a conservative management group and a surgical revascularization group in children with sickle cell disease and moyamoya syndrome (SCD-MMS). Despite more severe pretreatment disease, the surgery group had reduced odds of new CVEs after surgery and the odds of CVEs were significantly reduced after surgery compared to the presurgical period. These findings suggest that cerebral revascularization surgery, when added to conservative management, can reduce the risk of CVEs in patients with SCD-MMS.
PEDIATRIC BLOOD & CANCER
(2023)
Article
Pediatrics
Chiara Po, Margherita Nosadini, Marialuisa Zedde, Rosario Pascarella, Giuseppe Mirone, Domenico Cicala, Anna Rosati, Alessandra Cosi, Irene Toldo, Raffaella Colombatti, Paola Martelli, Alessandro Iodice, Patrizia Accorsi, Lucio Giordano, Salvatore Savasta, Thomas Foiadelli, Giuseppina Sanfilippo, Elvis Lafe, Federico Zappoli Thyrion, Gabriele Polonara, Serena Campa, Federico Raviglione, Barbara Scelsa, Stefania Maria Bova, Filippo Greco, Duccio Maria Cordelli, Luigi Cirillo, Francesco Toni, Valentina Baro, Francesco Causin, Anna Chiara Frigo, Agnese Suppiej, Laura Sainati, Danila Azzolina, Manuela Agostini, Elisabetta Cesaroni, Luigi De Carlo, Gabriella Di Rosa, Giacomo Esposito, Luisa Grazian, Giovanna Morini, Francesco Nicita, Francesca Felicia Operto, Dario Pruna, Paola Ragazzi, Massimo Rollo, Alberto Spalice, Pasquale Striano, Aldo Skabar, Luigi Alberto Lanterna, Andrea Carai, Carlo Efisio Marras, Renzo Manara, Stefano Sartori
Summary: The study retrospectively reviewed 65 pediatric patients with MMD/MMS in Italy and found that most patients presented neurological symptoms before diagnosis, with a considerable proportion experiencing further stroke events after surgical treatment, leading to poor outcomes.
FRONTIERS IN PEDIATRICS
(2022)
Article
Clinical Neurology
Haogeng Sun, Rui Tian, Zhiyuan Yu, Anqi Xiao, Chao You, Yi Liu
Summary: This study found that patients with MMD with IAs have different clinical and hemodynamic features compared to patients with MMD without IAs. CoW aneurysms and peripheral aneurysms may occur at different stages of MMD, leading to differences in anatomical location, type of hemorrhage, and treatment strategy.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Alaa Montaser, Ari D. Kappel, Jessica Driscoll, Emily Day, Madeline Karsten, Alfred P. See, Darren B. Orbach, Edward R. Smith
Summary: The purpose of this study was to describe a surgical technique for posterior cerebral revascularization in pediatric patients with moyamoya arteriopathy. A retrospective single-center series of pediatric patients with moyamoya disease was analyzed, and the results showed successful outcomes in terms of clinical and radiographic improvements after the surgical procedures.
CHILDS NERVOUS SYSTEM
(2023)
Article
Clinical Neurology
Eun Jin Ha, Ji Hoon Phi, Ji Yeoun Lee, Eun Jung Koh, Kyung Hyun Kim, Kyu-Chang Wang, Byung-Kyu Cho, Seung-Ki Kim
Summary: Indirect bypass can provide satisfactory long-term outcomes and prevent recurrent stroke in young children with MMD.