Article
Respiratory System
Mathew Cherian, Kate M. A. Magner, G. A. Whitmore, Katherine L. Vandemheen, J. Mark FitzGerald, Celine Bergeron, Louis-Philippe Boulet, Andreanne Cote, Stephen K. Field, Erika Penz, R. Andrew McIvor, Catherine Lemiere, Samir Gupta, Irvin Mayers, Mohit Bhutani, Paul Hernandez, M. Diane Lougheed, Christopher J. Licskai, Tanweer Azher, Martha Ainslie, Nicole Ezer, Sunita Mulpuru, Shawn D. Aaron
Summary: This study compares patient and physician characteristics between symptomatic individuals with undiagnosed obstructive lung disease (OLD) and individuals diagnosed with OLD. The results show that undiagnosed OLD patients have poorer lung function, greater psychosocial impacts on quality of life, and are less likely to receive appropriate investigations and specialist referral.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Critical Care Medicine
Andrea S. Gershon, Priscila Pequeno, Amanda Alberga Machado, Shawn D. Aaron, Tetyana Kendzerska, Jin Luo, Matthew B. Stanbrook, Wan C. Tan, Joan Porter, Teresa To
Summary: The study found that some individuals with COPD do not receive recommended medications, especially in the high-risk exacerbation group. Factors associated with nonreceipt of recommended medications include longer duration of COPD, comorbidities, dementia, and physician age. Targeting these factors could help improve care and health outcomes for people with COPD.
Article
Medicine, General & Internal
Sahar Zarabi, Teresa M. Chan, Mathew Mercuri, Clive Kearon, Michelle Turcotte, Emily Grusko, David Barbic, Catherine Varner, Eileen Bridges, Reaves Houston, Debra Eagles, Kerstin de Wit
Summary: This study conducted qualitative interviews with emergency physicians in Canada to explore their decision-making process regarding PE testing. It identified 8 key domains influencing physicians' choices, including anxiety with PE, barriers to using evidence, and divergent views on evidence-based testing. This conceptual framework provides insights for implementing evidence-based protocols for investigating PE.
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2021)
Article
Medicine, General & Internal
Idan Roifman, Lu Han, Jiming Fang, Anna Chu, Peter Austin, Dennis T. Ko, Pamela Douglas, Harindra Wijeysundera
Summary: Significant variability in initial stress testing strategy was found in Ontario, Canada. Physician-level factors were the key drivers of this variation, which could be addressed through educational campaigns to reduce the variability and improve guideline adherence.
Article
Health Care Sciences & Services
Arabella Simpkin Begin, Michael Hidrue, Sara Lehrhoff, Marcela G. del Carmen, Katrina Armstrong, Jason H. Wasfy
Summary: The study found that physicians with low tolerance of uncertainty are more likely to experience burnout, have lower career satisfaction, and are less engaged at work. Special attention should be paid to fields with less experience and higher uncertainty, such as primary care.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Respiratory System
Marina Guecamburu, Anaelle Coquelin, Amandine Rapin, Nelly Le Guen, Agnes Solomiac, Pauline Henrot, Marie Erbault, Sandrine Morin, Maeva Zysman
Summary: This study using the French nationally exhaustive health insurance database shows that the uptake of pulmonary rehabilitation after a severe COPD exacerbation is remarkably low and must become a high-priority management strategy.
RESPIRATORY RESEARCH
(2023)
Article
Multidisciplinary Sciences
Christina D. Svendsen, Karel K. J. Kuiper, Kristoffer Ostridge, Terje H. Larsen, Rune Nielsen, Vidar Hodneland, Eli Nordeide, Per S. Bakke, Tomas M. Eagan
Summary: COPD patients are more prone to coronary heart disease (CHD), but emphysema score, lung function, exacerbation frequency, and hypoxemia cannot predict the presence of significant coronary stenosis or calcium score (CaSc>100).
Article
Oncology
Shannon M. Blee, Rachel Pocock Shah, Ana P. M. Pinheiro, Jeffrey Switchenko, Margie Dixon, Taofeek K. Owonikoko, Charles E. Hill, Stephen M. Szabo, Rebecca D. Pentz
Summary: The study found that oncologists use variable terminology to describe molecular testing, which is often not understood by patients. White participants were more likely to understand genetic testing and mutation, while patients with higher family income were also more likely to understand the terms. The results highlight the importance of developing more effective methods to explain molecular testing terminology to patients.
Article
Public, Environmental & Occupational Health
Mufaro Kanyangarara, Virginie Daguise, Lidia Gual-Gonzalez, Alain H. Litwin, Jeffrey Korte, Connor Ross, Melissa S. Nolan
Summary: This study analyzed survey data to understand risk perceptions, testing practices, and preventive behaviors related to COVID-19 in South Carolina. The study found that individuals aged 50 and older, those who identified as Black/African American, were obese, or worked as frontline healthcare workers or nursing home staff were more likely to test positive for COVID-19. On the other hand, individuals who were concerned about the burden of COVID-19 in their community and their own risk of infection were less likely to test positive. Strategies to improve testing accessibility and address testing barriers should be implemented.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Multidisciplinary Sciences
Alireza Khabbazi, Rojin Farzaneh, Maryam Mahmoudi, Mohammad Shahil, Amirreza Jabbaripour Sarmadian, Elaheh Babapour, Leila Alizadeh, Raha Khabbazi, Masoud Nouri-Vaskeh
Summary: Cold intolerance, characterized by various symptoms in response to cold exposure, can significantly impact health-related quality of life. This study investigated the prevalence of cold intolerance and associated factors in the general population of Tabriz, revealing higher frequency in females and individuals with comorbidities.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Matthew A. Pappas, Daniel Sessler, Andrew D. Auerbach, Michael W. Kattan, Alex Milinovich, Eugene H. Blackstone, Michael B. Rothberg
Summary: The study found that decisions to refer patients for preoperative stress testing are influenced by various factors other than estimated perioperative risk and functional status. The frequency of preoperative stress testing has decreased over time, but remains highly provider-dependent.
Article
Environmental Sciences
Stephanie DeFlorio-Barker, Andrey Egorov, Genee S. Smith, Mark S. Murphy, Jason E. Stout, Andrew J. Ghio, Edward E. Hudgens, Kyle P. Messier, Jean-Marie Maillard, Elizabeth D. Hilborn
Summary: The study found that proximity to certain soil types (hydric and acidic) may be a risk factor for the increasing prevalence of pulmonary nontuberculous mycobacteria (NTM) disease in central North Carolina.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Endocrinology & Metabolism
Aya Bassatne, Mohammad H. Murad, Thomas Piggott, Matthew T. Drake, Maya Rahme, Ghada El-Hajj Fuleihan
Summary: This study evaluated the values, preferences, and attitudes of patients and physicians towards the treatment of hypercalcemia of malignancy (HCM), and provided valuable information for the development of clinical practice guidelines. The findings highlighted the importance of considering cost, acceptability, feasibility, and equity when treating HCM, and identified survival and resolution of HCM as the most important treatment outcomes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Oncology
Terry L. Ng, Amber Johnson, Raphael A. Nemenoff, Elena Hsieh, Andrea Abeyta Osypuk, Adrie van Bokhoven, Howard Li, D. Ross Camidge, Erin L. Schenk
Summary: Symptomatic early onset pulmonary events were observed in 3% to 6% of patients within 1 week of starting brigatinib at 90 mg daily for 7 days followed by 180 mg daily. A high incidence of DLCO reduction was noted during the first 8 days of treatment, with subsequent recovery despite continued dosing. Dyspnea and six-minute walk test results did not correlate with DLCO changes, while patients with PFT-defined EOPE had higher levels of activated neutrophils. Neutrophil activation levels may serve as a potential biomarker for predicting EOPE development.
JOURNAL OF THORACIC ONCOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Leticia Fernanda Tavares Sousa de Oliveira, Luciana Dias Chiavegato, Jaquelina Sonoe Ota Arakaki, Abilio Oscar Silva Reis, Alzira Maria Alves Melo, Elaine Brito Vieira, Regimar Carla Machado Ranzani, Vinicius Batista Santos
Summary: This study aimed to investigate the prevalence of sexual dysfunction in patients with pulmonary hypertension and its association with sociodemographic and clinical characteristics. The results showed that most patients self-reported sexual dysfunction, which was associated with older age, worse functional class, and decreased exercise capacity.
Letter
Critical Care Medicine
Shawn D. Aaron, George A. Whitmore
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2018)
Editorial Material
Critical Care Medicine
Shawn D. Aaron
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2018)
Review
Critical Care Medicine
Shawn D. Aaron, Louis Philippe Boulet, Helen K. Reddel, Andrea S. Gershon
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2018)
Review
Critical Care Medicine
Nermin Diab, Andrea S. Gershon, Don D. Sin, Wan C. Tan, Jean Bourbeau, Louis-Philippe Boulet, Shawn D. Aaron
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2018)
Article
Respiratory System
Victor Kim, Shawn D. Aaron
EUROPEAN RESPIRATORY JOURNAL
(2018)
Letter
Critical Care Medicine
Shawn D. Aaron
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2019)
Article
Respiratory System
Aditi Shah, Najib Ayas, Wan-Cheng Tan, Atul Malhotra, John Kimoff, Marta Kaminska, Shawn D. Aarong, Rachel Jen
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2020)
Editorial Material
Critical Care Medicine
Sanjay Sethi, Shawn D. Aaron
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2020)
Letter
Respiratory System
Tetyana Kendzerska, Shawn D. Aaron, Teresa To, Chris Licskai, Matthew B. Stanbrook, Mary-Ellen Hogan, Wan C. Tan, Jean Bourbeau, Andrea S. Gershon
EUROPEAN RESPIRATORY JOURNAL
(2021)
Letter
Critical Care Medicine
Andrea S. Gershon, Rachel E. McGihon, Jin Luo, Alina J. Blazer, Tetyana Kendzerska, Teresa To, Shawn D. Aaron
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Editorial Material
Respiratory System
Andrea Gershon, Katherine L. Vandemheen, Shawn Aaron
CANADIAN JOURNAL OF RESPIRATORY CRITICAL CARE AND SLEEP MEDICINE
(2022)
Article
Respiratory System
Lili Jiang, Tetyana Kendzerska, Shawn D. Aaron, Therese A. Stukel, Matthew B. Stanbrook, Wan Tan, Priscila Pequeno, Andrea S. Gershon
Summary: Real-world prescription of triple therapy often deviates from COPD guidelines, disregarding disease severity and prior treatment attempts.
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2022)
Article
Respiratory System
Faye Luc, Emily Prieur, G. A. Whitmore, Peter G. Gibson, Katherine L. Vandemheen, Shawn D. Aaron
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2019)
Article
Respiratory System
Tetyana Kendzerska, Richard S. Leung, Shawn D. Aaron, Najib Ayas, Jacqueline S. Sandoz, Andrea S. Gershon
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2019)
Review
Respiratory System
Manoj J. Mammen, David R. Lloyd, Sandeep Kumar, Anum S. Ahmed, Vandana Pai, Rajesh Kunadharaju, Shilpi Gupta, Linda Nici, Shawn D. Aaron, Paul E. Alexander
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2020)