Article
Oncology
Jian-Xun Chen, Ting-Yu Lu, Yu-Sen Lin, Hsin-Yuan Fang, Pin-Keng Shih
Summary: This study evaluates the impact of PET/CT on tumor recurrence in pN0 NSCLC patients with tumor less than 4 cm, indicating that the presence of positive lymph nodes on PET/CT scans is associated with a higher risk of recurrence. Factors such as tumor SUVmax, positive lymph nodes on PET/CT, and tumor differentiation are significant in predicting tumor recurrence in this patient population.
Review
Multidisciplinary Sciences
Fengling Hu, Chutong Lin, Hongling Chu, Peng Ren, Jingdi Wang, Shaohua Ma
Summary: This study conducted a systematic review and meta-analysis to evaluate the survival difference between N1h and N1p in patients with pN1M0 NSCLC. The results showed that patients with N1p metastasis had a better prognosis compared to those with N1h metastasis.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Di Zhou, Dongsheng Yue, Zhenfa Zhang, Pengfei Tian, Yingnan Feng, Zuo Liu, Bin Zhang, Meng Wang, Xiaoliang Zhao, Changli Wang
Summary: This study investigated the prognostic significance of station 4R lymph node (LN) dissection in patients with right primary non-small cell lung cancer (NSCLC). The results showed that station 4R dissection improved disease-free survival (DFS) and overall survival (OS) rates in these patients. These findings suggest that station 4R dissection should be recommended as a routine procedure for right primary NSCLC patients.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Medicine, General & Internal
Xiang Zhang, Nan Feng, Bo Wu, Yiping Wei, Wenxiong Zhang
Summary: Lymph node ratio (LNR) is an important prognostic indicator in non-small-cell lung cancer (NSCLC), with higher LNR indicating worse prognosis. This study found that LNR and positive node category have predictive value for prognosis in stage III NSCLC patients.
Article
Oncology
Zhicheng He, Zhihua Li, Song Xu, Weibing Wu, Quan Zhu, Jun Wang, Wei Wen, Liang Chen
Summary: This study aimed to identify the optimal number of examined lymph nodes (ELNs) in sublobar resection (SLR) and assess the survival differences between SLR with adequate ELNs and lobectomy. Results showed that SLR patients with an adequate ELN count had noninferior survival outcomes compared with lobectomy patients.
CLINICAL LUNG CANCER
(2021)
Article
Multidisciplinary Sciences
Kenichi Ishii, Jun Watanabe, Kouki Goto, Yusuke Suwa, Kazuya Nakagawa, Hirokazu Suwa, Mayumi Ozawa, Atsushi Ishibe, Chikara Kunisaki, Itaru Endo
Summary: The study investigated the impact of APN metastasis on the prognosis of patients with high-risk stage III colon cancer, revealing that APN metastasis is an independent risk factor for 5-year overall survival and relapse-free survival.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Donglai Chen, Qifeng Ding, Wei Wang, Xiaofan Wang, Xuejie Wu, Yiming Mao, Chang Chen, Yongbing Chen, Yongsheng Zhang
Summary: Extracapsular lymph node involvement (ECLNI) is a strong predictor of unfavorable overall survival (OS) and recurrence-free survival (RFS) for lung adenocarcinoma (LUAD) patients. Factors such as tumor spread through air spaces are associated with ECLNI presence. ECLNI status provides additional precision in stratifying pN1 and pN2 patients with significantly different RFS and OS outcomes.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Giovanni Maconi, Vera Sorin, Uri Kopylov, Oranit Barzilay, Francesca Ferretti, Silvia Innamorati, Massimo Tonolini, Rami Eliakim, Michel Marianne Amitai
Summary: Inflamed mesenteric lymph nodes in the jejunal mesentery detected by magnetic resonance enterography could be valuable in suggesting proximal small bowel disease in patients with Crohn's disease, even when imaging does not show disease involvement.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
(2022)
Review
Medicine, Research & Experimental
Jiajing Sun, Sikai Wu, Zixian Jin, Sijia Ren, William C. Cho, Chengchu Zhu, Jianfei Shen
Summary: Lung cancer has high morbidity and mortality rates, with tumor metastasis being a significant risk factor for death. Even after complete removal of a tumor at an early stage, there is still a risk of recurrence. Lymph node micrometastasis has been found to be associated with poor prognosis, but predicting prognosis and choosing the appropriate surgical and postoperative adjuvant chemotherapy options remain challenging for clinicians.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Letter
Medicine, General & Internal
Wilson W. L. Li, Stefan M. van der Heide, Ad F. T. M. Verhagen, Nasser Altorki, Xiaofei Wang, Thomas E. Stinchcombe
Summary: Altorki et al. found similar survival between peripheral stage IA non-small-cell lung cancer patients who underwent lobar resection and those who underwent sublobar resection. However, sublobar resection had a higher incidence of locoregional recurrence, without having the benefits of lower operative mortality, lower risk of complications, higher quality of life, and carrying a probable added risk of adverse events for recurrent disease treatment.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Sevinc Citak, Talha Dogruyol, Serkan Bayram, Mustafa Vayvada, Serda Kanbur Metin, Volkan Baysungur
Summary: This study aimed to evaluate the effect of lymph node dissection method on staging results, diagnosis of tumor metastasis, and survival rates in NSCLC patients. The results showed that it is easier to detect lymph node involvement without introducing formaldehyde, and it is recommended to perform lymph node dissection on fresh specimens.
JOURNAL OF CARDIOTHORACIC SURGERY
(2023)
Article
Oncology
Yongrui Bai, Ling Rong, Bin Hu, Xiumei Ma, Jiahui Wang, Haiyan Chen
Summary: Sole nodal involvement is insufficient to predict survival in early-stage cervical cancer. Factors such as pathology, T stage, number of pathologic lymph nodes, and neoadjuvant chemotherapy all play important roles in determining treatment outcomes. The combination of tumor and lymph node subcategories provides better prognostic discrimination.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, General & Internal
Beatrice Chia-Hui Shih, Jae Hyun Jeon, Jin-Haeng Chung, Hyun Jung Kwon, Jeong Hoon Lee, Woohyun Jung, Yoohwa Hwang, Sukki Cho, Kwhanmien Kim, Sanghoon Jheon
Summary: The study found that the presence of ENE was associated with advanced T stage, N2 subgroups, lymphatic invasion, and pneumonectomy. Multivariable analysis showed that old age, advanced T stage, N2 subgroups, and ENE presence were significant independent predictors of disease-free survival (DFS). The 5-year DFS rate was 21.4% in patients with ENE and 43.4% in patients without ENE.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Surgery
Lei Peng, Qian-Wen Shang, Han-Yu Deng, Zhen-Kun Liu, Wen Li, Yun Wang
Summary: Lymph node dissection is an important part of surgical treatment for early-stage non-small cell lung cancer (NSCLC). Lobectomy with systematic lymph node dissection (SLND) is currently the gold standard surgical treatment for early-stage NSCLC patients. However, lobe-specific lymph node dissection (L-SLND) has been shown to be an alternative therapy for carefully selected patients with early-stage NSCLC. This literature review summarizes the role of L-SLDN in treating early-stage NSCLC and aims to provide evidence for its application.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Oncology
Ziran Zhao, Yibo Gao, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He
Summary: This study evaluated the prognostic significance of the eighth edition TNM stage criteria in patients with combined small-cell lung cancer (C-SCLC) and found it to be reliable. Surgery was also found to have a significant impact on patients' prognosis.
FRONTIERS IN ONCOLOGY
(2023)