Article
Medicine, General & Internal
Anna Oliveras, Isabel Galceran, Albert Goday, Susana Vazquez, Laia Sans, Marta Riera, David Benaiges, Julio Pascual
Summary: The study revealed an improvement in AS one month post-bariatric surgery, which correlated with changes in blood pressure and RAAS components, but was less effective in patients with higher PWV.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Physiology
Hiroshi Kawano, Meiko Asaka, Kenta Yamamoto, Yuko Gando, Masayuki Konishi, Shizuo Sakamoto, Motohiko Miyachi, Mitsuru Higuchi
Summary: This study found that central AWV in endurance-trained athletes was greater than age-matched healthy control men, while dynamic and static compliance did not differ significantly between the two groups. These results suggest that AWV and arterial compliance are important indicators for assessing vascular adaptation to endurance training.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Physics, Applied
Jiahui Duan, Hao Xu, Jinjuan Xiang, Xiaolei Wang, Wenwu Wang
Summary: The HfO2-based Si ferroelectric field-effect transistor shows promise as an emerging memory device due to its low power consumption, high speed, compatibility with CMOS, and scalability. In this study, we explore the effect of minor loop operation on defect generation and find that it can effectively suppress trap generation, increasing the device's endurance.
APPLIED PHYSICS EXPRESS
(2022)
Article
Engineering, Electrical & Electronic
Lu Tai, Wei Wei, Pengpeng Sang, Xiaopeng Li, Guoqing Zhao, Pengfei Jiang, Peng Yuan, Qing Luo, Xuepeng Zhan, Jixuan Wu, Jiezhi Chen
Summary: This work focuses on studying the ferroelectric Hf0.5Zr0.5O2 (HZO) thin film with different designs of intercalation layers. Among the various intercalation stacks studied, HZO films with dual 0.05 nm titanium layers (DL-Ti) demonstrate ultrahigh remanent polarization (2P(r) ~ 57 μC/cm²), low coercive field (E-c ~ 1.1 MV/cm), and high breakdown field (E-BD ~ 4.3 MV/cm). The results show that atomic layer doping is an effective approach to engineer better performance and robust reliability in HZO-based devices.
IEEE ELECTRON DEVICE LETTERS
(2023)
Article
Environmental Sciences
Vanessa Santos, Luis Miguel Massuca, Vitor Angarten, Xavier Melo, Rita Pinto, Bo Fernhall, Helena Santa-Clara
Summary: Resistance training can increase arterial stiffness, while endurance training can decrease it. In this study, the time course of changes in arterial stiffness indices after high-volume combined endurance training and high-volume combined resistance training were compared. The results showed that endurance training decreased arterial stiffness, while resistance training increased it.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Lin Xu, Jiafu Wei, Jiani Liu, Yuan Feng, Lu Wang, Shiqi Wang, Qiao Li, Sen He, Yong Chen, Yong Peng, Yun Bao, Xuemei Yang, Chengqi He, Mao Chen, Quan Wei
Summary: This study tested the effects of inspiratory muscle training (IMT) plus usual cardiac rehabilitation (CR) in patients after transcatheter aortic valve replacement (TAVR). The results showed that IMT plus CR effectively improved exercise endurance, pulmonary ventilation function, and inspiratory muscle strength in TAVR patients and shortened the length of hospital stay.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tania C. Sluckin, Sanne-Marije J. A. Hazen, Karin Horsthuis, Doenja M. J. Lambregts, Regina G. H. Beets-Tan, Pieter J. Tanis, Miranda Kusters
Summary: This study aimed to evaluate the variation in measurements and anatomical classifications of lateral lymph nodes (LLNs) before and after training. The results showed that after training, there was an improvement in the correct identification of anatomical location and a reduction in the deviation of short-axis measurements. The conclusion of this study is that adequate training is crucial for the accurate evaluation of LLNs.
EUROPEAN RADIOLOGY
(2023)
Article
Cell Biology
Edmund Battey, Regula Furrer, Jacob Ross, Christoph Handschin, Julien Ochala, Matthew J. Stroud
Summary: PGC-1α plays a critical role in myonuclear accretion during adaptation to endurance training, especially in larger muscle fibers. Myonuclear accretion in PGC-1α mKO mice is slightly affected with increasing fiber size, but is significantly altered in trained larger fibers compared to sedentary mice, highlighting the importance of PGC-1α in myonuclear accretion in these fibers.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Article
Physiology
Mohammad Soltani, Masoud Jokar Baluchi, Daniel Boullosa, Ali Daraei, Patricia K. Doyle-Baker, Ayoub Saeidi, Beat Knechtle, Kambiz Moradi Dehbaghi, Shirin Shirzad Mollabashi, Trisha A. VanDusseldorp, Hassane Zouhal
Summary: This study investigated the chronic effects of high-volume moderate-intensity training (HVMIT) and low-volume high-intensity training (LVHIT) on heart rate variability (HRV) and arterial stiffness (AS) in sedentary adult men. LVHIT protocol was more efficient for improving HRV variables and PWV than HVMIT protocol after 12 weeks of continuous running training. Changes in some HRV parameters were related to changes in PWV, suggesting a potential link between central and peripheral cardiovascular adaptations.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Karin Vonbank, Daniel Haubenberger, Raphael Rosenhek, Matthias Schneider, Stefan Aschauer, Marco Idzko, Harald Gabriel
Summary: Endurance training significantly increased both peak oxygen uptake (peakVO(2)) and endurance capacity in patients with moderate-severe valvular heart disease.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Geriatrics & Gerontology
Tsubasa Tomoto, Rong Zhang
Summary: Advanced age is a major risk factor for dementia, including Alzheimer's disease. Arterial aging is closely associated with cerebrovascular dysfunction and brain aging, while aerobic exercise can improve cerebral blood flow and cerebrovascular function, thereby maintaining brain health in older adults.
Article
Medicine, General & Internal
Wei-Chun Huang, Chih-Yu Chen, Wei-Chih Liao, Biing-Ru Wu, Wei-Chun Chen, Chih-Yen Tu, Chia-Hung Chen, Wen-Chien Cheng
Summary: This study evaluated the efficacy of once-daily long-acting beta 2-agonist/long-acting muscarinic antagonist fixed-dose combinations for improving lung function in patients with chronic obstructive pulmonary disease (COPD). The results showed that all three treatment options significantly increased the forced expiratory volume in 1 s (FEV1), and treatment with tiotropium/olodaterol resulted in significant improvement in forced vital capacity (FVC%) and residual volume (RV%).
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Food Science & Technology
Harald Hefter, Beyza urer, Raphaela Brauns, Dietmar Rosenthal, Sven G. Meuth, John-Ih Lee, Philipp Albrecht, Sara Samadzadeh
Summary: This study compares CD patients who switched to incoBoNT/A after treatment failure with abo- or onabotulinum toxin type A (BoNT/A) to CD patients exclusively treated with incoBoNT/A. The results show significant long-term improvement after switching to incoBoNT/A, but not to the level achieved before treatment failure or in exclusive incoBoNT/A treatment. There was no difference in outcomes between abo- and onaBoNT/A pretreatments or between NAB-positive and NAB-negative patients.
Article
Medicine, General & Internal
Elena Pavlidou, Athanasios Kyrgidis, Konstantinos Vachtsevanos, Jannis Constantinidis, Stefanos Triaridis, Athanasia Printza
Summary: This study aimed to investigate the effectiveness of an eight-week training protocol paired with accuracy tasks and swallowing exercises in improving tongue strength and swallowing in patients after tongue resection. The results showed significant improvements in maximum isometric pressures, endurance, and swallowing pressures, as well as symptom and function assessments, in the treatment group compared to the follow-up control group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Jesus Mas Martinez, David Bustamante Suarez de Puga, Carmen Verdu-Roman, Enrique Martinez Gimenez, Manuel Morales Santias, Javier Sanz-Reig
Summary: This study aimed to evaluate outcomes in women undergoing hip arthroscopy for FAIS and found significant improvements in PROs in women at 4-year follow-up. Differences between women and men in PROs and rates of achieving MCID, SCB and PASS were predominantly significant for iHOT-12 PASS.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Letter
Clinical Neurology
Bruno Revol, Christel Castelli, Marie Joyeux-Faure, Jean-Louis Pepin
Article
Clinical Neurology
A. Leotard, M. Delorme, S. Hartley, C. Khouri, M. Lebret, F. Lofaso, J-L Pepin, J-C Borel
Summary: This study found that in patients with neuromuscular diseases, higher levels of ventilatory support were associated with lower carbon dioxide pressure. Further research is needed to assess the impact of assistance levels on disease progression.
SLEEP AND BREATHING
(2023)
Article
Medical Laboratory Technology
Denis Monneret, Robert L. Stavis
Summary: This study aimed to estimate the probability of arterial or venous source of umbilical cord blood gases in depressed newborn infants. The results showed that the probability can be estimated based on pH, pCO(2), and pO(2) in most acidemic specimens.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Letter
Medical Laboratory Technology
Charles R. Lefevre, Charles Gibert, Laure Maucorps, Josephine Vasse, Marie Michel, Marine Chupin, Fanny Zhao, Laurent Desmurs, Nicolas Collet, Mathilde Di Filippo, Regine Cartier, Denis Monneret, Oriane Marmontel
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Respiratory System
Renaud Tamisier, Jean-Louis Pepin, Holger Woehrle, Muriel Salvat, Gilles Barone-Rochette, Cecile Rocca, Eik Vettorazzi, Helmut Teschler, Martin Cowie, Patrick Levy
Summary: This study investigated the effect of ASV on sympathetic tone in patients with HFrEF and CSA. The results showed that ASV did not effectively suppress sympathetic activation in heart failure patients and was associated with increased cardiovascular mortality.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Editorial Material
Respiratory System
Patrick Levy, Sophia Schiza
EUROPEAN RESPIRATORY JOURNAL
(2023)
Letter
Respiratory System
Renaud Tamisier, Jean-Louis Pepin, Patrick Levy
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Atul Malhotra, Kate V. V. Cole, Anita S. S. Malik, Jean-Louis Pepin, Fatima H. Sert H. Kuniyoshi, Peter A. A. Cistulli, Adam V. V. Benjafield, Virend K. K. Somers
Summary: This study assessed the impact of adherence to positive airway pressure (PAP) therapy on health care resource utilization in patients with obstructive sleep apnea (OSA) and heart failure with reduced ejection fraction. The results indicated that adherent patients had a reduction in emergency room visits and lower healthcare costs compared to nonadherent patients. These findings suggest that diagnosing and effectively treating OSA with PAP should be emphasized in patients with heart failure with reduced ejection fraction.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Review
Respiratory System
Monique Mendelson, Jeremy Duval, Francois Bettega, Renaud Tamisier, Sebastien Baillieul, Sebastien Bailly, Jean-Louis Pepin
Summary: CPAP is the first-line therapy for OSA, but adherence is a major issue, with up to 50% discontinuing CPAP within 3 years. This article discusses the individual and societal costs of non-adherence, factors associated with non-adherence, and strategies for improving adherence, including telehealth and behavioral interventions. Challenges in visualization and analysis of CPAP remote monitoring platforms are also addressed. Expert opinion highlights the need for tailored strategies to improve CPAP adherence, as well as the importance of refining visualization dashboards and utilizing telehealth and innovative analytics.
EXPERT REVIEW OF RESPIRATORY MEDICINE
(2023)
Article
Clinical Neurology
Ami-Marie Bocoum, Sebastien Bailly, Marie Joyeux-Faure, Sebastien Baillieul, Francois Arbib, Clara-Lou Kang, Van Ngo, Pierre Boutouyrie, Renaud Tamisier, Jean Louis Pepin
Summary: This observational study aimed to analyze the association between long-term continuous positive airway pressure (CPAP) adherence and cardiovascular outcomes. The study found that long-term CPAP adherence was positively associated with a reduction in all-cause mortality, but it did not significantly affect the occurrence of cardiovascular events.
Article
Cardiac & Cardiovascular Systems
Peter A. Cistulli, Atul Malhotra, Kate V. Cole, Anita S. Malik, Jean-Louis Pepin, Fatima Sert H. Kuniyoshi, Adam V. Benjafield, Virend K. Somers
Summary: This study examined the association between adherence to positive airway pressure (PAP) therapy and healthcare resource use in heart failure with preserved ejection fraction (HFpEF) patients with obstructive sleep apnea (OSA). The results showed that adherent patients had lower healthcare resource use, a decrease in hospitalizations by 57%, a decrease in emergency room visits by 36%, and lower total healthcare costs compared to nonadherent patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Health Care Sciences & Services
Jean-Louis Pepin, Pauline Lemeille, Helene Denis, Anne Josseran, Florent Lavergne, Arnaud Panes, Sebastien Bailly, Alain Palot, Arnaud Prigent
Summary: This study investigated the health trajectories of individuals with COPD before initiating at-home NIV and compared mortality outcomes between different pre-NIV health trajectory groups. The findings revealed significant heterogeneity in clinical initiation of NIV, indicating the lack of strong evidence and guideline recommendations. Knowledge about these different clusters should be used to promote more consistent and personalized use of domiciliary NIV in COPD.
LANCET REGIONAL HEALTH-EUROPE
(2023)
Article
Health Care Sciences & Services
Francois Bughin, Monique Mendelson, Dany Jaffuel, Jean-Louis Pepin, Frederic Gagnadoux, Frederic Goutorbe, Beatriz Abril, Bronia Ayoub, Alexandre Aranda, Khuder Alagha, Pascal Pomies, Francois Roubille, Jacques Mercier, Nicolas Molinari, Yves Dauvilliers, Nelly Heraud, M. Hayot
Summary: This study aims to assess the potential benefits of a telerehabilitation program implemented at continuous positive airway pressure initiation compared to continuous positive airway pressure alone and usual care on symptoms and cardiometabolic risk factors of obstructive sleep apnea syndrome. The study is a 6-months multicenter randomized controlled trial including 180 obese patients with severe obstructive sleep apnea syndrome.
Article
Clinical Neurology
Jeremy Duval, Clementine Mouroux, Sophie Foury, Jean-Louis Pepin, Sebastien Bailly
SLEEP AND BREATHING
(2023)
Article
Clinical Neurology
Kimberly L. Sterling, Naomi Alpert, Peter A. Cistulli, Jean-Louis Pepin, Suyog More, Kate V. Cole, Atul Malhotra
Summary: Obstructive sleep apnea (OSA) is a prevalent yet underdiagnosed disease that poses a significant economic burden on the US healthcare system. This retrospective study found that adherence to positive airway pressure (PAP) therapy is associated with reduced healthcare resource utilization and costs, providing additional evidence for the diagnosis and long-term treatment of OSA.
JOURNAL OF SLEEP RESEARCH
(2023)