Review
Respiratory System
Ye Lu, Wei Zheng, Wei Cao, Xianghong Yang, Li Zhao, Yu Chen
Summary: This case report highlights a rare comorbidity of AFOP secondary to Sjogren's syndrome and Legionella infection. The patient showed significant improvement in clinical symptoms and lung imaging after a short course of low-dose corticosteroid therapy.
BMC PULMONARY MEDICINE
(2022)
Review
Pathology
Haihong Chen, Yukun Kuang, Xinyan Huang, Ziyin Ye, Yangli Liu, Canmao Xie, Ke-Jing Tang
Summary: AFOP is a rare histologic interstitial pneumonia pattern characterized by intra-alveolar fibrin deposition and organizing pneumonia. Clinical characteristics remain unclear and treatment consensus is lacking. Prednisone shows good clinical response in AFOP cases.
DIAGNOSTIC PATHOLOGY
(2021)
Article
Medicine, General & Internal
Dingyuan Jiang, Xueying Chen, Jun Li, Ling Zhao, Huaping Dai
Summary: Acute fibrinous and organizing pneumonia (AFOP) is a rare lung disease that is difficult to diagnose and its etiology is unclear. This case report presents a young male with AFOP, initially misdiagnosed as community-acquired pneumonia. Further investigation revealed underlying myelodysplastic syndrome (MDS) and hemophagocytic lymphohistiocytosis (HLH). Despite treatment with glucocorticoids and chemotherapy, the patient did not show improvement. Early identification and diagnosis of AFOP in patients with hematological diseases are crucial, and more research is needed for the management of severe AFOP.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Dorcas Lim, Sok Boon Tay
Summary: We present the case of a middle-aged male who had a left retrocardiac opacity on a chest radiograph. Further thorax CT examination revealed multiple subpleural lesions with central necrosis. Histopathological examination of the subpleural lesions confirmed the diagnosis of acute fibrinous organizing pneumonia. The patient responded well to corticosteroid treatment, and repeat CT showed resolution of the subpleural lesions.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Review
Respiratory System
Xiang Zhao, Yuan Cheng, Yan Xiong, Guangfa Wang
Summary: Acute fibrinous and organizing pneumonia (AFOP) is a rare interstitial pneumonia characterized by fibrin balls and organizing pneumonia in the alveoli. The diagnosis and treatment of AFOP are currently uncertain. It is important to adjust the treatment plan based on the patient's symptoms, test results, and response to treatment for an accurate diagnosis and optimal treatment efficacy.
CLINICAL RESPIRATORY JOURNAL
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Jong Hyuk Lee, Ho-Kee Yum, Fady Jamous, Claudia Santos, Alessio Campisi, Salim Surani, Filippo Lococo, Jin Mo Goo, Soon Ho Yoon
Summary: This study evaluated the clinico-radiological findings of AFOP and identified prognostic predictors based on whether a surgical or non-surgical biopsy was performed. Patients diagnosed via surgical biopsy had different symptomatic presentations and prognosis compared to those diagnosed via non-surgical biopsy. Patients with patchy or mass-like air-space consolidation on CT images showed a better prognosis in AFOP cases.
EUROPEAN RADIOLOGY
(2021)
Review
Infectious Diseases
Songhua Hu, Xudan Yang, Yaqin Huang, Zhihao Xu
Summary: Broncholithiasis coupled with Aspergillus infection is a rare disease with complex pathogenesis and non-specific clinical manifestations, often leading to misdiagnosis and incorrect treatment. We present a rare case of asymptomatic broncholithiasis with Aspergillus infection and discuss its diagnosis, differential diagnosis, and follow-up. Our study, together with other relevant research, provides valuable insights for improving physicians' awareness and future management of these conditions.
INFECTION AND DRUG RESISTANCE
(2023)
Review
Medicine, General & Internal
Jiayuan Ye, Yilian Xie, Yaojiang Xu, Nan Chen, Yifei Tu
Summary: Oxaliplatin is a commonly used agent in neoadjuvant chemotherapy for gastrointestinal tract tumors, but it can cause idiopathic non-cirrhotic portal hypertension (INCPH). This study presents a case report of INCPH induced by oxaliplatin chemotherapy and provides insight into its clinical manifestations and treatment strategies, highlighting the importance for physicians to consider the risk of INCPH when prescribing oxaliplatin.
FRONTIERS IN MEDICINE
(2023)
Review
Public, Environmental & Occupational Health
Ali Al-kassab-Cordova, Patricia Valdiviezo-Polo, Juan R. Ulloque-Badaracco, Carlos L. Honorio-Arroyo, Miguel Hueda-Zavaleta, Vicente A. Benites-Zapata
Summary: This study describes a case report of C. lapagei in Peru and systematically reviews documented case reports of individuals infected with C. lapagei worldwide. The study found that C. lapagei has been reported in 20 cases between 2006 and 2022, primarily presenting with fever and pneumonia, and showing sensitivity to quinolones, tetracyclines, and carbapenems as potential treatment options.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2023)
Review
Medicine, General & Internal
Fabio Del Duca, Aniello Maiese, Federica Spina, Giacomo Visi, Raffaele La Russa, Paola Santoro, Maria Serenella Pignotti, Paola Frati, Vittorio Fineschi
Summary: Acute idiopathic pulmonary hemorrhage in infants (AIPHI) is a rare and poorly understood disease with high lethality. We report a case of a 2-day-old male who died suddenly from acute pulmonary hemorrhage. Autopsy and histological analysis revealed alveolar spaces filled with red blood cells and hyaline membranes, supporting the diagnosis of AIPHI. A systematic review of scientific literature showed only 61 reported cases, with symptoms including acute respiratory distress, upper airway bleeding, hemoptysis, epistaxis, and hematemesis. Autopsy findings included lower airway hemorrhages and hemosiderin-laden macrophages. Our findings and literature data are crucial for accurate diagnosis, and we propose autoptic criteria for post-mortem diagnosis of AIPHI.
Review
Microbiology
Igor Dumic, Emily Person, Oladapo Igandan, Omobolanle Adetimehin, Charles W. Nordstrom, Christopher Williams, Fnu Shweta
Summary: An immunocompetent patient with community-acquired pneumonia caused by Anaplasma phagocytophilum is reported. The patient presented with fever, cough, and shortness of breath, and imaging showed lung infiltrates. Extensive investigations confirmed anaplasmosis and the patient recovered with doxycycline therapy. Empiric treatments without doxycycline in anaplasmosis pneumonia cases can lead to acute respiratory distress syndrome, therefore clinicians should be aware of this unusual presentation and initiate appropriate antimicrobial regimens.
Review
Infectious Diseases
Fabricio Malaguez Webber, Arun Nachiappan, Freddy Duarte Lau, Christie Costello, Saul Zane
Summary: This article presents a case of pulmonary nocardiosis caused by Nocardia caishijiensis in a patient with HIV infection. The patient was successfully treated with amikacin and thrimetroprim-sulfametoxazole. This is the first reported case of Nocardia caishijiensis infection in humans in North America and highlights the potential importance of this pathogen in nocardiosis, especially in solid organ transplant recipients.
BMC INFECTIOUS DISEASES
(2023)
Review
Immunology
Siqiang Niu, Limin Zhao
Summary: Legionella pneumonia is a life-threatening, severe multi-system disease caused by Legionella pneumophila. Accurate etiological diagnosis is crucial for treatment strategies, and metagenomic next-generation sequencing (mNGS) proves to be a promising tool for rapid and precise diagnosis.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Review
Medicine, General & Internal
Jiaming Liu, Yuan Gao
Summary: This article reports a case of severe pneumonia caused by C. psittaci, which was diagnosed using mNGS and successfully treated. The article summarizes the etiology, clinical manifestations, diagnosis, and treatment strategies of severe C. psittaci pneumonia, aiming to raise awareness among clinicians regarding this disease.
FRONTIERS IN MEDICINE
(2022)
Review
Respiratory System
Jiali Ji, Hongqin Zhong, Xian Ren, Ting He, Guijuan Xie, Xun Wang
Summary: This article reports a rare case of endobronchial myelolipoma, in which the patient was treated with cryobiopsy and argon plasma coagulation (APC) and experienced symptom relief. The article highlights the importance of pathological biopsy in diagnosing endobronchial myelolipoma.
BMC PULMONARY MEDICINE
(2023)
