Inhibiting an Epoxide Hydrolase Virulence Factor fromPseudomonas aeruginosaProtects CFTR

Pseudomonas aeruginosa Reduces VX-809 Stimulated F508del-CFTR Chloride Secretion by Airway Epithelial Cells

(2015) Bruce A. Stanton et al.   PLoS One

Signature Motifs Identify anAcinetobacterCif Virulence Factor with Epoxide Hydrolase Activity

(2014) Christopher D. Bahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial

(2014) Michael P Boyle et al.   Lancet Respiratory Medicine

Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries

(2012) Christophe Morisseau et al.   ANALYTICAL BIOCHEMISTRY

Prevalence of Streptococci and Increased Polymicrobial Diversity Associated with Cystic Fibrosis Patient Stability

(2012) L. M. Filkins et al.   JOURNAL OF BACTERIOLOGY

Epoxide-Mediated CifR Repression of cif Gene Expression Utilizes Two Binding Sites in Pseudomonas aeruginosa

(2012) A. E. Ballok et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa Cif Defines a Distinct Class of α/β Epoxide Hydrolases Utilizing a His/Tyr Ring-Opening Pair

(2012) Christopher D. Bahl et al.   PROTEIN AND PEPTIDE LETTERS

Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies

(2011) Christophe Morisseau et al.   ANALYTICAL BIOCHEMISTRY

Cystic Fibrosis Transmembrane Conductance Regulator Intracellular Processing, Trafficking, and Opportunities for Mutation-Specific Treatment

(2011) Mark P. Rogan et al.   CHEST

A Pseudomonas aeruginosa Toxin that Hijacks the Host Ubiquitin Proteolytic System

(2011) Jennifer M. Bomberger et al.   PLoS Pathogens

Epoxyeicosatrienoic Acid Analogs and Vascular Function

(2010) V. Sudhahar et al.   CURRENT MEDICINAL CHEMISTRY

Protein secretion systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons

(2010) Sophie Bleves et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Crystal Structure of the Cystic Fibrosis Transmembrane Conductance Regulator Inhibitory Factor Cif Reveals Novel Active-Site Features of an Epoxide Hydrolase Virulence Factor

(2010) C. D. Bahl et al.   JOURNAL OF BACTERIOLOGY

Epoxyeicosatrienoic acids and endothelium-dependent responses

(2010) William B. Campbell et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted byPseudomonas aeruginosa

(2009) Christopher D. Bahl et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Bugs, Biofilms, and Resistance in Cystic Fibrosis

(2009) Jane C Davies   Respiratory Care

Long-Distance Delivery of Bacterial Virulence Factors by Pseudomonas aeruginosa Outer Membrane Vesicles

(2009) Jennifer M. Bomberger et al.   PLoS Pathogens

Pseudomonas aeruginosain Chronic Obstructive Pulmonary Disease

(2008) Timothy F. Murphy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Aerosol antibiotics: considerations in pharmacological and clinical evaluation

(2008) Michael N Dudley et al.   CURRENT OPINION IN BIOTECHNOLOGY

Cif Is Negatively Regulated by the TetR Family Repressor CifR

(2008) D. P. MacEachran et al.   INFECTION AND IMMUNITY

Thyroid dysfunction due to over-the-counter usage of tiratricol

(2008) R. C. W. Ma et al.   INTERNAL MEDICINE JOURNAL