Article
Mathematical & Computational Biology
Havard Molversmyr, Ove Oyas, Filip Rotnes, Jon Olav Vik
Summary: Constraint-based models (CBMs) are widely used to study metabolic networks. However, most CBMs are generic and do not capture the differences in reaction activities between different contexts. In this study, six model extraction methods were used to create context-specific models for Atlantic salmon based on transcriptomic data. The results showed that certain methods outperformed others in terms of functional accuracy, and the context-specific models consistently performed better than the generic model.
NPJ SYSTEMS BIOLOGY AND APPLICATIONS
(2023)
Article
Engineering, Environmental
Quang Tri Ho, Sylvia Frantzen, Bente M. Nilsen, Ole Jakob Nostbakken, Atabak M. Azad, Arne Duinker, Lise Madsen, Michael S. Bank
Summary: This study investigated the bioaccumulation of persistent organic pollutants (POPs) in marine fish from the North-East Atlantic Ocean (NEAO). It was found that POPs congener composition profiles were mainly influenced by fish species rather than geographical location. The study also revealed that factors such as fat content, fish size, trophic position, and latitude had an impact on POPs concentrations in fish. Additionally, a non-linear relationship between POPs concentrations and fat content was observed, with concentrations reaching saturation when fat content exceeded 10%.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Multidisciplinary Sciences
Yoandy Coca, Marcos Godoy, Juan Pablo Pontigo, Diego Caro, Vinicius Maracaja-Coutinho, Raul Arias-Carrasco, Leonardo Rodriguez-Cordova, Marco Montes de Oca, Cesar Saez-Navarrete, Ian Burbulis
Summary: An unbalanced gut microbiota in fish may promote bacterial infections. However, the interactions between different bacterial groups and their effects on fish health are not well understood. This study found that pathogenic species were present in the digestive tract and gut mucosa of healthy salmon, and the dysbiosis in sick salmon may be associated with cooperative interactions between different taxonomic families of bacteria, leading to clinical symptoms.
SCIENTIFIC REPORTS
(2023)
Article
Engineering, Marine
Bibbi Maria Kallay Hjelle, Albert Kjartan Dagbjartarson Imsland, Pablo Vigo Balseiro, Sigurd Olav Handeland
Summary: The AcuLice system, which uses a composite acoustic sound image, has been shown to effectively reduce the number of salmon lice on Atlantic salmon without causing additional stress to the fish.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Immunology
Byron Morales-Lange, Felipe Ramirez-Cepeda, Paulina Schmitt, Fanny Guzman, Leidy Lagos, Margareth Overland, Valentina Wong-Benito, Monica Imarai, Derie Fuentes, Sebastian Boltana, Javier Alcaino, Carlos Soto, Luis Mercado
Summary: This study investigated the effect of IFN gamma on the expression of cell-surface markers on splenocytes of Atlantic salmon. The results showed that IFN gamma could stimulate the gene expression and protein availability of cell-surface markers, enhancing the function of immune cells. In vivo experiments demonstrated that during a natural outbreak of Piscirickettsia salmonis, the expression of IFN gamma in Atlantic salmon increased simultaneously with the up-regulation of cell-surface markers.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
O. Gervais, A. Barria, A. Papadopoulou, R. L. Gratacap, B. Hillestad, A. E. Tinch, S. A. M. Martin, D. Robledo, R. D. Houston
Summary: The study found that the heritability of ISAV resistance is moderate with a polygenic architecture, but a significant quantitative trait locus was detected on chromosome 13. A mild up-regulation of the interferon pathway characterizes the response to the virus in heart samples from this population of Atlantic salmon, and candidate genes showing differential expression between samples with high and low breeding values for resistance were identified.
Article
Cell Biology
F. L. Almeida, K. O. Skaftnesmo, E. Andersson, L. Kleppe, R. B. Edvardsen, B. Norberg, P. G. Fjelldal, T. J. Hansen, R. W. Schulz, A. Wargelius
Summary: The genetic introgression of farmed salmon into wild populations can harm genetic integrity. To address this issue, researchers have identified the potential role of the Piwil1 protein in germ cell survival in Atlantic salmon. By inducing mutations in Piwil1 using CRISPR-Cas9, they observed a mosaic pattern of mutations in the F0 generation of salmon. These mutants still carried germ cells but exhibited partial germ cell loss and delays in spermatogenesis. Further analysis revealed the importance of the N domain of Piwil1 for its function. By generating F1 fish with different combinations of mutated alleles, they found that complete loss of Piwil1 led to the absence of germ cells, while heterozygous fish displayed an intermediate phenotype with a higher ratio of somatic cells to germ cells.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Biochemical Research Methods
Maksim Zakhartsev, Filip Rotnes, Marie Gulla, Ove Oyas, Jesse C. J. van Dam, Maria Suarez-Diez, Fabian Grammes, Robert Anton Hafthorsson, Wout van Helvoirt, Jasper J. Koehorst, Peter J. Schaap, Yang Jin, Liv Torunn Mydland, Arne B. Gjuvsland, Simen R. Sandve, Vitor A. P. Martins dos Santos, Jon Olav Vik
Summary: SALARECON is a model that links the genome of Atlantic salmon to metabolic fluxes and growth, allowing for the simulation of metabolism and growth. It can be used to explain Atlantic salmon physiology and address key challenges in aquaculture.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Green & Sustainable Science & Technology
Mark T. Brown, Silvio Viglia, Dave Love, Frank Asche, Elizabeth Nussbaumer, Jillian Fry, Ray Hilborn, Roni Neff
Summary: This study examines the environmental dependency and sustainability of wild caught sockeye salmon fishery in Alaska and Atlantic salmon aquaculture in Norway. The results indicate that labor and services have a significant impact on both production systems at the processing stage, with a high emergy sustainability index (ESI) for the sockeye fishery.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Multidisciplinary Sciences
Tormod Haraldstad, Thrond O. Haugen, Esben M. Olsen, Torbjorn Forseth, Erik Hoglund
Summary: Renewable energy projects like hydropower plants contribute to meeting energy demands and mitigating climate change, but they can alter environments and impact fish migration conditions, affecting population adaptations. Monitoring Atlantic salmon smolts at a hydropower plant showed that behavioral traits influenced their choice between fish passage and turbine intake during migration, with potential implications for genetic diversity and future challenges.
SCIENTIFIC REPORTS
(2021)
Article
Fisheries
Raul Jimenez-Guerrero, Grete Baeverfjord, Oystein Evensen, Kristin Hamre, Thomas Larsson, Jens-Erik Dessene, Kjellrun-Hoas Gannestad, Turid Morkore
Summary: Focal dark spots (DS) are a common quality problem in farmed Atlantic salmon, and this study examines the association between abnormal rib morphology and DS types, as well as the frequency of rib abnormalities. Rib abnormalities were found in most fish, with an increase in abnormal ribs after transfer to sea-cages. Abnormalities in farmed salmon were concentrated in the center and distal parts of ribs, similar to the distribution of DS.
Article
Chemistry, Physical
Milda Gumbyte, Violeta Makareviciene, Egle Sendzikiene
Summary: In this experimental study, biodiesel was synthesized from salmon oil using Lipozyme(R)RM IM as a biocatalyst. Isoamyl alcohol was used as an acyl acceptor in the transesterification process. The aim of the study was to optimize process conditions to achieve the highest transesterification degree. Response surface methodology was used for statistical analysis and process parameter optimization. The optimal parameters for biodiesel synthesis were determined, resulting in a transesterification degree of 87.23%. The further addition of isoamyl alcohol during the transesterification process increased the degree to 96.5%.
Article
Fisheries
Marc H. G. Berntssen, Grethe Rosenlund, Borja Garlito, Heidi Amlund, Nini H. Sissener, Annette Bernhard, Monica Sanden
Summary: The use of plant-based feeds in fish farming has introduced undesirable substances such as pesticides. Research indicates that commercially produced Atlantic salmon feed may contain unsafe levels of the pesticide pirimiphos-methyl (PM-m), leading to adverse effects on fish health. Fish fed with PM-m spiked feeds showed growth reduction, oxidative stress, liver damage, and disturbances in lipid metabolism. Safe limits for dietary PM-m were determined through dose-response analysis, setting the daily safe dose for fish consumption.
Article
Biology
Petri T. Niemela, Ines Klemme, Anssi Karvonen, Pekka Hyvarinen, Paul Debes, Jaakko Erkinaro, Marion Sinclair-Waters, Victoria L. Pritchard, Laura S. Harkonen, Craig R. Primmer
Summary: Research shows that there are differences in activity expression among Atlantic salmon life-history genotypes. The vgll3*E allele is associated with increased activity in females, while the vgll3*L allele is associated with increased activity in males. These sex-dependent effects may contribute to maintaining genetic life-history variation within populations.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Green & Sustainable Science & Technology
Nigel Guerra, Christopher C. Parrish, Minmin Wei, Judy Perry, Roberto E. Armenta, Stefanie M. Colombo
Summary: A 16-week feeding trial was conducted to investigate the effects of replacing dietary fish oil (FO) with docosahexaenoic acid (DHA)-rich microbial oil (MO) on membrane lipid composition of Atlantic salmon parr liver and muscle tissues. The study found significant differences in the proportions of omega 3 and omega 6 fatty acids in both liver and muscle tissues when FO was completely replaced with MO, suggesting that MO could be a potential substitute for FO in the diet of farmed Atlantic salmon.
Article
Environmental Sciences
Julia Farkas, Trond Nordtug, Linn H. Svendheim, Elettra D. Amico, Emlyn J. Davies, Tomasz Ciesielski, Bjorn Munro Jenssen, Torstein Kristensen, Pal A. Olsvik, Bjorn Henrik Hansen
Summary: This study investigates the impacts of tailings from a calcium carbonate processing plant on early live stages of haddock and Atlantic cod. Results show that mineral particles adhere to fish eggs, affecting egg buoyancy, survival, and development. Tailing exposure induced early hatching, reduced survival, and caused malformations in larvae, particularly in cod.
ENVIRONMENTAL RESEARCH
(2021)
Article
Green & Sustainable Science & Technology
Leticia Regueiro, Richard Newton, Mohamed Soula, Diego Mendez, Bjorn Kok, David C. Little, Roberto Pastres, Johan Johansen, Martina Ferreira
Summary: EU aquaculture only meets a small fraction of internal demand for aquatic foods, but boosting this industry must adhere to high standards of environmental protection and social benefits. However, evaluating the environmental sustainability of aquaculture and other food production systems is complex due to various tools and approaches available.
JOURNAL OF INDUSTRIAL ECOLOGY
(2022)
Article
Environmental Sciences
Linn H. Svendheim, Tjalling Jager, Pal A. Olsvik, Ida Beathe Overjordet, Tomasz M. Ciesielski, Trond Nordtug, Torstein Kristensen, Bjorn Henrik Hansen, Bjarne Kvaestad, Dag Altin, Julia Farkas
Summary: This study investigated the effects of mine tailing exposure on marine copepods and found that exposure led to slower growth and reduced lipid accumulation. The presence of metals and processing chemicals did not influence these responses, suggesting that uptake of mineral particles was responsible for the observed effects. The applied dynamic energy budget (DEB) model confirmed that ingestion of tailing particles while feeding can result in less energy being available for growth and development.
Article
Environmental Sciences
Stefania Piarulli, Bjorn Henrik Hansen, Tomasz Ciesielski, Anna-Lena Zocher, Arne Malzahn, Pal A. Olsvik, Christian Sonne, Trond Nordtug, Bjorn Munro Jenssen, Andy M. Booth, Julia Farkas
Summary: Rare earth elements and yttrium are critical elements with potential environmental impacts when released into marine ecosystems. Current research gaps exist in understanding the distribution and effects of anthropogenic REY, particularly at the organismal level, highlighting the need for further scientific attention and risk assessment in marine environments.
ENVIRONMENTAL POLLUTION
(2021)
Article
Food Science & Technology
Madhushri S. Varunjikar, Carlos Moreno-Ibarguen, Juan S. Andrade-Martinez, Hui-Shan Tung, Ikram Belghit, Magnus Palmblad, Pal A. Olsvik, Alejandro Reyes, Josef D. Rasinger, Kai K. Lie
Summary: The study shows that both DNA and protein-based approaches can efficiently tackle current challenges in feed and food authentication analyses.
Article
Engineering, Environmental
Shubham Varshney, Adnan H. Gora, Prabhugouda Siriyappagouder, Viswanath Kiron, Pal A. Olsvik
Summary: The study found that 6PPD quinone is toxic to zebrafish larvae, but no significant mortality was observed at the tested concentrations, resulting in a dose-dependent reduction in swimming performance. Exposure to environmentally relevant concentrations (1 µg/L) of 6PPD and 6PPD quinone did not affect the behavior of zebrafish embryos, while exposure to higher but sublethal concentrations (10 and 25 µg/L) can impact behavioral endpoints.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Fisheries
Barry Antonio Costa-Pierce, Abigail B. Bockus, Bela H. Buck, Sander W. K. van den Burg, Thierry Chopin, Joao G. Ferreira, Nils Goseberg, Kevin G. Heasman, Johan Johansen, Sandra E. Shumway, Neil A. Sims, Albert G. J. Tacon
Summary: The article highlights the importance of considering the future of aquaculture and makes suggestions for policies and investments. It emphasizes freshwater aquaculture as a more favorable production strategy compared to marine aquaculture and opposes open ocean aquaculture and other industrial-intensive forms of aquaculture.
REVIEWS IN FISHERIES SCIENCE & AQUACULTURE
(2022)
Article
Fisheries
Kristin Hamre, Giulia Micallef, Marie Hillestad, Johan Johansen, Sofie Remo, Wuxiao Zhang, Elisabeth Odegard, Pedro Araujo, Antony J. Prabhu Philip, Rune Waagbo
Summary: The hypothesis of this study was that increased growth in spring, stimulated by temperature and daylength, leads to oxidative stress and changes in antioxidant utilization in Atlantic salmon. The study found that vitamin E and vitamin C concentrations decreased in the spring and were restored in the autumn, while astaxanthin concentration remained constant during the spring and summer and increased in the autumn. Cataract and melanin spots were observed during the spring and early summer. However, the concentrations of malondialdehyde and astaxanthin did not support the hypothesis, and more data is needed to draw conclusions on the effects of oxidative stress on melanin spots.
Article
Fisheries
Christina Hoerterer, Jessica Petereit, Gisela Lannig, Johan Johansen, Gabriella Pereira, Luis E. C. Conceicao, Roberto Pastres, Bela H. Buck
Summary: In Europe, turbot aquaculture has the potential for sustainable production, but the low tolerance to fishmeal replacement poses a challenge. This study investigated the effects of more sustainable feed formulations on the growth and feed performance of juvenile turbot. The results showed that replacing fishmeal with processed animal proteins had a negative effect on feed performance, while replacing it with terrestrial plant proteins affected the nutritional status of the fish.
AQUACULTURE INTERNATIONAL
(2022)
Article
Food Science & Technology
L. Softeland, P. A. Olsvik
Summary: A novel 3D co-culture model using hepatocytes and kidney epithelial cells from the same fish was developed. Glyphosate exposure was found to alter lipid metabolism in both hepatocytes and kidney cells. The 3D hepatocyte cell culture showed superior response compared to 2D culture and was used in co-culture with kidney cells.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Green & Sustainable Science & Technology
Silvio Cristiano, Hallstein Baarset, Christian Bruckner, Johan Johansen, Roberto Pastres
Summary: Two Life-Cycle Assessments were conducted to evaluate the environmental performances of selected novel eco-intensification innovations for sludge and fish mortality treatment. The results showed that these innovations compare well with established processes, with a decrease in most impact categories and an increase in water consumption. The analysis also provided insights for improving their environmental performances.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Environmental Sciences
Isabel S. Abihssira-Garcia, Tanja Kogel, Alessio Gomiero, Torstein Kristensen, Morten Krogstad, Pal A. Olsvik
Summary: This study investigated the interactions between microplastics and persistent organic pollutants (POPs) in relation to Atlantic salmon farming. The results showed that microplastics can sorb POPs from aquafeeds and potentially act as vectors of these chemicals in the marine environment, thereby increasing the environmental impact of fish farming.
MARINE POLLUTION BULLETIN
(2022)
Article
Green & Sustainable Science & Technology
Jessica Petereit, Christina Hoerterer, Adrian A. Bischoff-Lang, Luis E. C. Conceicao, Gabriella Pereira, Johan Johansen, Roberto Pastres, Bela H. Buck
Summary: This study examines the impact of alternative feed formulations on European seabass and finds that these concepts are more sustainable compared to commercial feed. Additionally, the alternative formulations do not affect fillet quality or animal welfare, which are increasingly important factors in aquaculture.
Article
Toxicology
Pal A. Olsvik, Sonnich Meier, Xiaokang Zhang, Anders Goksoyr, Odd Andre Karlsen, Fekadu Yadetie
Summary: This study aimed to compare the mode of action of environmentally relevant concentrations of mixtures of halogenated compounds in Atlantic cod in North Sea and North Atlantic coastal areas. The results showed that halogenated compounds activated the unfolded protein response (UPR) pathway in cod. There was no additive effect observed when cod were exposed to mixtures of all three compound groups.
JOURNAL OF APPLIED TOXICOLOGY
(2023)
Article
Fisheries
Pal A. Olsvik, Kristine E. Brokke, Ole B. Samuelsen, Rita Hannisdal
Summary: This study investigates the uptake and toxicity of Lufenuron in liver tissue of Atlantic salmon. The results show that Lufenuron easily bioaccumulates and induces a transient inhibition of transcription in the liver of salmon.
JOURNAL OF FISH DISEASES
(2023)