The impact of next-generation sequencing technologies on HLA research

Cost-efficient multiplex PCR for routine genotyping of up to nine classical HLA loci in a single analytical run of multiple samples by next generation sequencing

(2015) Yuki Ozaki et al.   BMC GENOMICS

HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data

(2015) Naoki Nariai et al.   BMC GENOMICS

Impact of three Illumina library construction methods on GC bias and HLA genotype calling

(2015) James H. Lan et al.   HUMAN IMMUNOLOGY

Development of a high-resolution NGS-based HLA-typing and analysis pipeline

(2015) M. Wittig et al.   NUCLEIC ACIDS RESEARCH

HLAreporter: a tool for HLA typing from next generation sequencing data

(2015) Yazhi Huang et al.   Genome Medicine

OptiType: precision HLA typing from next-generation sequencing data

(2014) András Szolek et al.   BIOINFORMATICS

A Bead-based Normalization for Uniform Sequencing depth (BeNUS) protocol for multi-samples sequencing exemplified by HLA-B

(2014) Kazuyoshi Hosomichi et al.   BMC GENOMICS

Genomic selection accuracies within and between environments and small breeding groups in white spruce

(2014) Jean Beaulieu et al.   BMC GENOMICS

High-throughput multiplex HLA genotyping by next-generation sequencing using multi-locus individual tagging

(2014) Philip K Ehrenberg et al.   BMC GENOMICS

Next generation sequencing to determine HLA class II genotypes in a cohort of hematopoietic cell transplant patients and donors

(2014) Anajane G. Smith et al.   HUMAN IMMUNOLOGY

HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies in Saudis using next generation sequencing technique

(2014) A. H. Hajeer et al.   TISSUE ANTIGENS

Application of high-throughput, high-resolution and cost-effective next generation sequencing-based large-scale HLA typing in donor registry

(2014) M. Zhou et al.   TISSUE ANTIGENS

Phase-defined complete sequencing of the HLA genes by next-generation sequencing

(2013) Kazuyoshi Hosomichi et al.   BMC GENOMICS

Rapid, scalable and highly automated HLA genotyping using next-generation sequencing: a transition from research to diagnostics

(2013) Martin Danzer et al.   BMC GENOMICS

Momentum grows to make 'personalized' medicine more 'precise'

(2013) Alla Katsnelson   NATURE MEDICINE

ATHLATES: accurate typing of human leukocyte antigen through exome sequencing

(2013) Chang Liu et al.   NUCLEIC ACIDS RESEARCH

Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping

(2013) Steven Ringquist et al.   PLoS One

HLA Haplotyping from RNA-seq Data Using Hierarchical Read Weighting

(2013) Hyunsung John Kim et al.   PLoS One

HLA Typing from 1000 Genomes Whole Genome and Whole Exome Illumina Data

(2013) Endre Major et al.   PLoS One

High throughput HLA genotyping using 454 sequencing and the Fluidigm Access Array™ system for simplified amplicon library preparation

(2013) P. V. Moonsamy et al.   TISSUE ANTIGENS

HLA-DRB1, -DRB3, -DRB4 and -DRB5 genotyping at a super-high resolution level by long range PCR and high-throughput sequencing

(2013) Y. Ozaki et al.   TISSUE ANTIGENS

Ultra-high resolution HLA genotyping and allele discovery by highly multiplexed cDNA amplicon pyrosequencing

(2012) Simon M Lank et al.   BMC GENOMICS

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Next-generation sequencing: impact of exome sequencing in characterizing Mendelian disorders

(2012) Bahareh Rabbani et al.   JOURNAL OF HUMAN GENETICS

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

High-throughput, high-fidelity HLA genotyping with deep sequencing

(2012) C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ENCODE Project Writes Eulogy for Junk DNA

(2012) E. Pennisi   SCIENCE

Super high resolution for single molecule-sequence-based typing of classical HLA loci at the 8-digit level using next generation sequencers

(2012) T. Shiina et al.   TISSUE ANTIGENS

HLA typing from RNA-Seq sequence reads

(2012) Sebastian Boegel et al.   Genome Medicine

Derivation of HLA types from shotgun sequence datasets

(2012) René L Warren et al.   Genome Medicine

Next-generation sequencing for HLA typing of class I loci

(2011) Rachel L Erlich et al.   BMC GENOMICS

A multi-site study using high-resolution HLA genotyping by next generation sequencing

(2011) C. L. Holcomb et al.   TISSUE ANTIGENS

A novel single cDNA amplicon pyrosequencing method for high-throughput, cost-effective sequence-based HLA class I genotyping

(2010) Simon M. Lank et al.   HUMAN IMMUNOLOGY

Next-generation sequencing: the solution for high-resolution, unambiguous human leukocyte antigen typing

(2010) C. Lind et al.   HUMAN IMMUNOLOGY

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

(2010) Akihiro Fujimoto et al.   NATURE GENETICS

Rapid high-throughput human leukocyte antigen typing by massively parallel pyrosequencing for high-resolution allele identification

(2009) Christian Gabriel et al.   HUMAN IMMUNOLOGY

The HLA genomic loci map: expression, interaction, diversity and disease

(2009) Takashi Shiina et al.   JOURNAL OF HUMAN GENETICS

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

(2009) Andreas Gnirke et al.   NATURE BIOTECHNOLOGY

High-resolution, high-throughput HLA genotyping by next-generation sequencing

(2009) G. Bentley et al.   TISSUE ANTIGENS

High Sensitivity of Human Leukocyte Antigen–B*5701 as a Marker for Immunologically Confirmed Abacavir Hypersensitivity in White and Black Patients

(2008) Michael Saag et al.   CLINICAL INFECTIOUS DISEASES

Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project

(2008) Roger Horton et al.   IMMUNOGENETICS

The complete genome of an individual by massively parallel DNA sequencing

(2008) David A. Wheeler et al.   NATURE

The diploid genome sequence of an Asian individual

(2008) Jun Wang et al.   NATURE

Accurate whole human genome sequencing using reversible terminator chemistry

(2008) David R. Bentley et al.   NATURE