Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin

Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria

(2014) Antonio M. Risitano et al.   BLOOD

Genetic and Intervention Studies Implicating Complement C3 as a Major Target for the Treatment of Periodontitis

(2014) T. Maekawa et al.   JOURNAL OF IMMUNOLOGY

Inhibition of biomaterial-induced complement activation attenuates the inflammatory host response to implantation

(2013) Ioannis Kourtzelis et al.   FASEB JOURNAL

Complement in Immune and Inflammatory Disorders: Pathophysiological Mechanisms

(2013) D. Ricklin et al.   JOURNAL OF IMMUNOLOGY

Complement in Immune and Inflammatory Disorders: Therapeutic Interventions

(2013) D. Ricklin et al.   JOURNAL OF IMMUNOLOGY

New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties

(2012) Hongchang Qu et al.   IMMUNOBIOLOGY

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis

(2010) R. Silasi-Mansat et al.   BLOOD

Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis

(2010) I. Kourtzelis et al.   BLOOD

Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

(2010) Hongchang Qu et al.   MOLECULAR IMMUNOLOGY

Strategies to prolong the plasma residence time of peptide drugs

(2010) Lisa Pollaro et al.   MedChemComm

Development, Characterization, and Evaluation of a Fusion Protein of a Novel Glucagon-Like Peptide-1 (GLP-1) Analog and Human Serum Albumin inPichia pastoris

(2009) Zhihui GAO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Improving the pharmacokinetics/pharmacodynamics of prolactin, GH, and their antagonists by fusion to a synthetic albumin-binding peptide

(2009) John F Langenheim et al.   JOURNAL OF ENDOCRINOLOGY

Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin

(2009) Paola Magotti et al.   JOURNAL OF MOLECULAR RECOGNITION

A Portable Albumin Binder from a DNA-Encoded Chemical Library

(2008) Christoph E. Dumelin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

(2008) Felix Kratz   JOURNAL OF CONTROLLED RELEASE

Validation of a Rapid Equilibrium Dialysis Approach for the Measurement of Plasma Protein Binding

(2008) Nigel J. Waters et al.   JOURNAL OF PHARMACEUTICAL SCIENCES