An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion

4-[18F]Fluoro-N-methyl-N-(propyl-2-yn-1-yl)benzenesulfonamide ([18F]F-SA): a versatile building block for labeling of peptides, proteins and oligonucleotides with fluorine-18 via Cu(I)-mediated click chemistry

(2013) Theres Ramenda et al.   AMINO ACIDS

HTS by NMR of Combinatorial Libraries: A Fragment-Based Approach to Ligand Discovery

(2013) Bainan Wu et al.   CHEMISTRY & BIOLOGY

Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo

(2012) Torsten Kniess et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure-Activity Relationships and Mechanism of Action of Eph-ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor

(2012) Massimiliano Tognolini et al.   ChemMedChem

Fluorine-18 Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine-based Radiotracer Targeting the Receptor Tyrosine Kinase EphB4

(2012) Constantin Mamat et al.   ChemMedChem

Novel Targeted System To Deliver Chemotherapeutic Drugs to EphA2-Expressing Cancer Cells

(2012) Si Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM)

(2011) Torsten Kniess et al.   APPLIED RADIATION AND ISOTOPES

Radiolabeling of phosphatidylserine-binding peptides with prosthetic groups N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM) and N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)

(2011) Janice Kapty et al.   APPLIED RADIATION AND ISOTOPES

In Vivo Small-Animal PET/CT of EphB4 Receptors Using 64Cu-Labeled Peptide

(2011) C. Xiong et al.   JOURNAL OF NUCLEAR MEDICINE

Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation

(2011) Carmine Giorgio et al.   PLoS One

1-(3-[18F]fluoropropyl)piperazines as model compounds for the radiofluorination of pyrido[2,3-d]pyrimidines

(2011) P. Grosse-Gehling et al.   RADIOCHIMICA ACTA

Targeting Eph receptors with peptides and small molecules: Progress and challenges

(2011) Roberta Noberini et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Synthesis, structure determination, and (radio-)fluorination of novel functionalized phosphanes suitable for the traceless Staudinger ligation

(2011) Constantin Mamat et al.   TETRAHEDRON

The EphB2 tumor suppressor induces autophagic cell death via concomitant activation of the ERK1/2 and PI3K pathways

(2010) Mustapha Kandouz et al.   CELL CYCLE

The traceless Staudinger ligation with fluorine-18: a novel and versatile labeling technique for the synthesis of PET-radiotracers

(2010) Marc Pretze et al.   TETRAHEDRON LETTERS

One-Pot Approach to Well-Defined Biomolecular Assemblies by Orthogonal Chemoselective Ligations

(2009) Mathieu Galibert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hexadentate Bispidine Derivatives as Versatile Bifunctional Chelate Agents for Copper(II) Radioisotopes▽

(2009) Stefanie Juran et al.   BIOCONJUGATE CHEMISTRY

Radiolabelling of proteins with fluorine-18 via click chemistry

(2009) Theres Ramenda et al.   CHEMICAL COMMUNICATIONS

Structure-Based Optimization of Potent and Selective Inhibitors of the Tyrosine Kinase Erythropoietin Producing Human Hepatocellular Carcinoma Receptor B4 (EphB4)

(2009) Karine Lafleur et al.   JOURNAL OF MEDICINAL CHEMISTRY

Methods for 18F-labeling of RGD peptides: comparison of aminooxy [18F]fluorobenzaldehyde condensation with ‘click labeling’ using 2-[18F]fluoroethylazide, and S-alkylation with [18F]fluoropropanethiol

(2008) Matthias Glaser et al.   AMINO ACIDS

Systematic comparison of two novel, thiol-reactive prosthetic groups for 18F labeling of peptides and proteins with the acylation agent succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)

(2008) Frank Wuest et al.   AMINO ACIDS

Inhibitors of the tyrosine kinase EphB4. Part 2: Structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines

(2008) Catherine Bardelle et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors

(2008) Roberta Noberini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA-fiber EPR spectroscopy as a tool to study DNA–metal complex interactions: DNA binding of hydrated Cu(II) ions and Cu(II) complexes of amino acids and peptides

(2008) Makoto Chikira   JOURNAL OF INORGANIC BIOCHEMISTRY