Discovery of Potent HDAC Inhibitors Based on Chlamydocin with Inhibitory Effects on Cell Migration

Mechanisms of G1 cell cycle arrest and apoptosis in myeloma cells induced by hybrid-compound histone deacetylase inhibitor

(2013) Seiko Fujii et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

(2013) Christopher J. Millard et al.   MOLECULAR CELL

Histone deacetylase inhibitor, apicidin, inhibits human ovarian cancer cell migration via class II histone deacetylase 4 silencing

(2012) Mee Young Ahn et al.   CANCER LETTERS

Synthesis, evaluation and molecular modeling of cyclic tetrapeptide histone deacetylase inhibitors as anticancer agents

(2012) Dawei Huang et al.   JOURNAL OF PEPTIDE SCIENCE

Histone deacetylases and cancer

(2012) Bruna Barneda-Zahonero et al.   Molecular Oncology

A Novel Class of Small Molecule Inhibitors of HDAC6

(2011) Elizabeth S. Inks et al.   ACS Chemical Biology

HDAC4-Regulated STAT1 Activation Mediates Platinum Resistance in Ovarian Cancer

(2011) E. A. Stronach et al.   CANCER RESEARCH

Comparative analysis of the role of small G proteins in cell migration and cell death: Cytoprotective and promigratory effects of RalA

(2011) Hyejin Jeon et al.   EXPERIMENTAL CELL RESEARCH

Epigenomics of leukemia: from mechanisms to therapeutic applications

(2011) Cristina Florean et al.   Epigenomics

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides

(2010) Jerome C. Bressi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Language of Histone Crosstalk

(2010) Jung-Shin Lee et al.   CELL

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation

(2009) Reinhard Brunmeir et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Histone Deacetylase Inhibitors in Cancer Therapy

(2009) Andrew A. Lane et al.   JOURNAL OF CLINICAL ONCOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation

(2008) Romain Debret et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Chemical Origins of Isoform Selectivity in Histone Deacetylase Inhibitors

(2008) Alan Kozikowski et al.   CURRENT PHARMACEUTICAL DESIGN

Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

(2008) Matthew J. Bottomley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Series of Potent and Selective, Triazolylphenyl-Based Histone Deacetylases Inhibitors with Activity against Pancreatic Cancer Cells andPlasmodium falciparum

(2008) Yufeng Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Specific Activity of Class II Histone Deacetylases in Human Breast Cancer Cells

(2008) V. Duong et al.   MOLECULAR CANCER RESEARCH

HDAC6: a key regulator of cytoskeleton, cell migration and cell–cell interactions

(2008) Agustín Valenzuela-Fernández et al.   TRENDS IN CELL BIOLOGY

Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs)

(2007) Stefan Schäfer et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The regulation of matrix metalloproteinases and their inhibitors

(2007) I CLARK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY