Intermolecular and Intramolecular Hydrogen Bonds Involving Fluorine Atoms: Implications for Recognition, Selectivity, and Chemical Properties

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: Exploration of effective compounds in arthritis models

(2011) Hiroki Shimizu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Matched Molecular Pairs as a Medicinal Chemistry Tool

(2011) Ed Griffen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mapping the Reaction Coordinates of Enzymatic Defluorination

(2011) Peter W. Y. Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

1-Deoxy-1-fluoro-L-galactitol

(2010) Sarah F. Jenkinson et al.   ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE

A Bond by Any Other Name

(2010) Gautam R. Desiraju   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity

(2010) Amy M. Weeks et al.   BIOCHEMISTRY

Fluorine-Protein Interactions and 19F NMR Isotropic Chemical Shifts: An Empirical Correlation with Implications for Drug Design

(2010) Claudio Dalvit et al.   ChemMedChem

Structural Basis for the Activity and Substrate Specificity of Fluoroacetyl-CoA Thioesterase FlK

(2010) Marcio V. B. Dias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lead Optimization Using Matched Molecular Pairs: Inclusion of Contextual Information for Enhanced Prediction of hERG Inhibition, Solubility, and Lipophilicity

(2010) George Papadatos et al.   Journal of Chemical Information and Modeling

19F NMR chemical shift prediction with fluorine fingerprint descriptor

(2010) Anna Vulpetti et al.   JOURNAL OF FLUORINE CHEMISTRY

N-Methyl Phenylalanine-Rich Peptides as Highly Versatile Blood−Brain Barrier Shuttles

(2010) Morteza Malakoutikhah et al.   JOURNAL OF MEDICINAL CHEMISTRY

Intramolecular Hydrogen Bonding in Medicinal Chemistry

(2010) Bernd Kuhn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Halogenated β,γ-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase β: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues

(2010) Vinod K. Batra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Energetically Important C−H···F−C Pseudohydrogen Bonding in Water: Evidence and Application to Rational Design of Oligonucleotides with High Binding Affinity

(2010) Maryam Yahyaee Anzahaee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N–H⋯F hydrogen bonds in fluorinated benzanilides: NMR and DFT study

(2010) G. N. Manjunatha Reddy et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Combined use of computational chemistry, NMR screening, and X-ray crystallography for identification and characterization of fluorophilic protein environments

(2010) Anna Vulpetti et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Trisubstituted pyrimidine derivatives from tetrafluoropyrimidine

(2010) Emma L. Parks et al.   TETRAHEDRON

Design and NMR-Based Screening of LEF, a Library of Chemical Fragments with Different Local Environment of Fluorine

(2009) Anna Vulpetti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Determinants of the Unexpected Stability of RNA Fluorobenzene Self Pairs

(2008) Hannes Kopitz et al.   CHEMBIOCHEM

Central Nervous System Drugs: Low Temperature X-ray Structures of (I) the Base 5-(2,3-Dichlorophenyl)-2,4-diamino-6-fluoromethyl-pyrimidine (4030W92) and (II) 5-(2,6-Dichlorophenyl)-1-H-2,4-diamino-6-methyl-pyrimidine methanesulphonic acid salt (227C89)

(2008) Rex A. Palmer et al.   JOURNAL OF CHEMICAL CRYSTALLOGRAPHY

A fluorine scan of non-peptidic inhibitors of neprilysin: Fluorophobic and fluorophilic regions in an enzyme active site

(2008) Martin Morgenthaler et al.   JOURNAL OF FLUORINE CHEMISTRY

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Evaluation of the interchangeability of C–H and C–F groups: insights from crystal packing in a series of isomeric fluorinated benzanilides

(2007) Deepak Chopra et al.   CRYSTENGCOMM