Discovery, Synthesis, and in vitro Evaluation of West Nile Virus Protease Inhibitors Based on the 9,10-Dihydro-3H,4aH-1,3,9,10a-tetraazaphenanthren-4-one Scaffold

Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors

(2010) Yisheng Lai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis, and In Vitro Evaluation of Potential West Nile Virus Protease Inhibitors Based on the 1-Oxo-1,2,3,4-tetrahydroisoquinoline and 1-Oxo-1,2-dihydroisoquinoline Scaffolds

(2010) Dengfeng Dou et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Structure–activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase

(2009) Shyama Sidique et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic Access to Poly-Substituted 6-Alkoxyindoles from 1,3-Cyclohexanediones and Nitroolefins through Facile Aromatization Reaction

(2009) Li-Jian Ma et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery of a Non-Peptidic Inhibitor of West Nile Virus NS3 Protease by High-Throughput Docking

(2009) Dariusz Ekonomiuk et al.   PLoS Neglected Tropical Diseases

Identification and Biochemical Characterization of Small-Molecule Inhibitors of West Nile Virus Serine Protease by a High-Throughput Screen

(2008) N. H. Mueller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Substrate Inhibition Kinetic Model for West Nile Virus NS2B-NS3 Protease†

(2008) Suzanne M. Tomlinson et al.   BIOCHEMISTRY

Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase

(2008) I. Radichev et al.   JOURNAL OF GENERAL VIROLOGY

Potent Cationic Inhibitors of West Nile Virus NS2B/NS3 Protease With Serum Stability, Cell Permeability and Antiviral Activity

(2008) Martin J. Stoermer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Victims of West Nile virus face long-term health problems

(2008) Genevive Bjorn   NATURE MEDICINE

Clinical Investigation of Hospitalized Human Cases of West Nile Virus Infection in Houston, Texas, 2002–2004

(2008) Kristy O. Murray et al.   VECTOR-BORNE AND ZOONOTIC DISEASES