Discovering Small-Molecule Estrogen Receptor α/Coactivator Binding Inhibitors: High-Throughput Screening, Ligand Development, and Models for Enhanced Potency

Probing the Topological Tolerance of Multimeric Protein Interactions: Evaluation of an Estrogen/Synthetic Ligand for FK506 Binding Protein Conjugate

(2010) Terry W. Moore et al.   BIOCONJUGATE CHEMISTRY

Improvement of Pharmacological Properties of Irreversible Thyroid Receptor Coactivator Binding Inhibitors

(2009) Jong Yeon Hwang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Minireview: Not Picking Pockets: Nuclear Receptor Alternate-Site Modulators (NRAMs)

(2009) Terry W. Moore et al.   MOLECULAR ENDOCRINOLOGY

Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor

(2008) Andrew L. LaFrate et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Do enthalpy and entropy distinguish first in class from best in class?

(2008) E FREIRE   DRUG DISCOVERY TODAY

MM-GB/SA Rescoring of Docking Poses in Structure-Based Lead Optimization

(2008) Cristiano R. W. Guimarães et al.   Journal of Chemical Information and Modeling

Potent Non-Nucleoside Inhibitors of the Measles Virus RNA-Dependent RNA Polymerase Complex

(2008) Aiming Sun et al.   JOURNAL OF MEDICINAL CHEMISTRY

Blocking Estrogen Signaling After the Hormone: Pyrimidine-Core Inhibitors of Estrogen Receptor-Coactivator Binding

(2008) Alexander A. Parent et al.   JOURNAL OF MEDICINAL CHEMISTRY

Microsecond Molecular Dynamics Simulation Shows Effect of Slow Loop Dynamics on Backbone Amide Order Parameters of Proteins†

(2008) Paul Maragakis et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Role of the Active-Site Solvent in the Thermodynamics of Factor Xa Ligand Binding

(2008) Robert Abel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic control of slow water transport by aquaporin 0: Implications for hydration and junction stability in the eye lens

(2008) M. O. Jensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA