Efflux Pump Inhibitors: A Strategy to Combat P-Glycoprotein and the NorA Multidrug Resistance Pump

1-Benzyl-1,2,3,4-tetrahydroisoquinoline Derivatives and Optically Pure Isomers as Novel Promising Multidrug Resistance (MDR) Reversing Agents

(2016) Lingjing Xue et al.   Letters in Drug Design & Discovery

3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization

(2009) Allen J. Duplantier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bacterial resistance modifying tetrasaccharide agents from Ipomoea murucoides

(2009) Lilia Chérigo et al.   PHYTOCHEMISTRY

Piperine analogs as potent Staphylococcus aureus NorA efflux pump inhibitors

(2008) Payare L. Sangwan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Citral derived amides as potent bacterial NorA efflux pump inhibitors

(2008) Niranjan Thota et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure–activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus

(2008) Joseph I. Ambrus et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and evaluation of PSSRI-based inhibitors of Staphylococcus aureus multidrug efflux pumps

(2008) Nadezhda German et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and synthesis of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer

(2008) Yu Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps

(2008) Nadezhda German et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Bicalutamide failure in prostate cancer treatment: Involvement of Multi Drug Resistance proteins

(2008) Nicola Antonio Colabufo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities

(2008) Marta Martins et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS

(2008) Michael F. Wempe et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Novel structural analogues of piperine as inhibitors of the NorA efflux pump of Staphylococcus aureus

(2008) A. Kumar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

DFT and GA Studies on the QSAR of 2-aryl-5-nitro-1H-indole derivatives as NorA Efflux Pump Inhibitors

(2008) Yujie Dai et al.   JOURNAL OF MOLECULAR MODELING

Direct Synthesis of Chrysosplenol D

(2008) George Kraus et al.   JOURNAL OF NATURAL PRODUCTS

Impact of Novel MDR Modulators on Human Cancer Cells: Reversal Activities and Induction Studies

(2008) Claudius Coburger et al.   PHARMACEUTICAL RESEARCH

Reversal of p-glycoprotein-mediated multidrug resistance by macrocyclic bisbibenzyl derivatives in adriamycin-resistant human myelogenous leukemia (K562/A02) cells

(2008) Xia Li et al.   TOXICOLOGY IN VITRO

New-generation efflux pump inhibitors

(2008) Martin Werle et al.   Expert Review of Clinical Pharmacology

Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives

(2007) Nicola Antonio Colabufo et al.   BIOORGANIC & MEDICINAL CHEMISTRY