Synthesis of Functionalized Aryl Fluorides Using Organolithium Reagents in Flow Microreactors

Suzuki-Miyaura Cross-Coupling Reactions in Flow: Multistep Synthesis Enabled by a Microfluidic Extraction

(2011) Timothy Noël et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereoselective Chain-Elongation Reactions Using Microreactors for Applications in Complex Molecule Assembly

(2011) Catherine F. Carter et al.   CHEMISTRY-A EUROPEAN JOURNAL

Flow microreactor synthesis of disubstituted pyridines from dibromopyridines via Br/Li exchange without using cryogenic conditions

(2011) Aiichiro Nagaki et al.   GREEN CHEMISTRY

Asymmetric Carbolithiation of Conjugated Enynes: A Flow Microreactor Enables the Use of Configurationally Unstable Intermediates before They Epimerize

(2011) Yutaka Tomida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Perfluoroalkylation in flow microreactors: generation of perfluoroalkyllithiums in the presence and absence of electrophiles

(2011) Aiichiro Nagaki et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Continuous Photochemical Generation of Catalytically Active [CpRu]+Complexes from CpRu(η6-C6H6)PF6

(2011) Alicia C. Gutierrez et al.   ORGANIC LETTERS

A New Enabling Technology for Convenient Laboratory Scale Continuous Flow Processing at Low Temperatures

(2011) Duncan L. Browne et al.   ORGANIC LETTERS

A flow-microreactor approach to protecting-group-free synthesis using organolithium compounds

(2011) Heejin Kim et al.   Nature Communications

Flash synthesis of TAC-101 and its analogues from 1,3,5-tribromobenzene using integrated flow microreactor systems

(2011) Aiichiro Nagaki et al.   RSC Advances

Convenient Electrophilic Fluorination of Functionalized Aryl and Heteroaryl Magnesium Reagents

(2010) Shigeyuki Yamada et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cross-Coupling in a Flow Microreactor: Space Integration of Lithiation and Murahashi Coupling

(2010) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Integrated Microreactors for Reaction Automation: New Approaches to Reaction Development

(2010) Jonathan P. McMullen et al.   Annual Review of Analytical Chemistry

Flash chemistry: flow microreactor synthesis based on high-resolution reaction time control

(2010) Jun-Ichi Yoshida   CHEMICAL RECORD

Synthesis of micro and nanostructures in microfluidic systems

(2010) Samuel Marre et al.   CHEMICAL SOCIETY REVIEWS

A Flow Microreactor System Enables Organolithium Reactions without Protecting Alkoxycarbonyl Groups

(2010) Aiichiro Nagaki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Green and Sustainable Chemical Synthesis Using Flow Microreactors

(2010) Jun-ichi Yoshida et al.   ChemSusChem

Silver-Catalyzed Late-Stage Fluorination

(2010) Pingping Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic and Scale-Up Investigations of Epoxide Aminolysis in Microreactors at High Temperatures and Pressures

(2010) Nikolay Zaborenko et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science

Nitro-Substituted Aryl Lithium Compounds in Microreactor Synthesis: Switch between Kinetic and Thermodynamic Control

(2009) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic CC, CN, and CO Ullmann-Type Coupling Reactions

(2009) Florian Monnier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Synthesis of Aryl Fluorides

(2009) Pazhamalai Anbarasan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of unsymmetrically substituted biaryls via sequential lithiation of dibromobiaryls using integrated microflow systems

(2009) Aiichiro Nagaki et al.   Beilstein Journal of Organic Chemistry

Oxiranyl Anion Methodology Using Microflow Systems

(2009) Aiichiro Nagaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Integrated microfluidic reactors

(2009) Wei-Yu Lin et al.   Nano Today

Formation of ArF from LPdAr(F): Catalytic Conversion of Aryl Triflates to Aryl Fluorides

(2009) D. A. Watson et al.   SCIENCE

Metal-free electrophilic fluorination of alkyl trifluoroborates and boronic acids

(2009) Clément Cazorla et al.   TETRAHEDRON LETTERS

Aryllithium Compounds Bearing Alkoxycarbonyl Groups: Generation and Reactions Using a Microflow System

(2008) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Flash Chemistry: Fast Chemical Synthesis by Using Microreactors

(2008) Jun-ichi Yoshida et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Microflow-System-Controlled Anionic Polymerization of Styrenes

(2008) Aiichiro Nagaki et al.   MACROMOLECULES

Selective Monolithiation of Dibromobiaryls Using Microflow Systems

(2008) Aiichiro Nagaki et al.   ORGANIC LETTERS

Spurring Radical Reactions of Organic Halides with Tin Hydride and TTMSS Using Microreactors

(2008) Takahide Fukuyama et al.   ORGANIC LETTERS

Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

(2008) Kenneth L. Kirk   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS