Combining Oxidative N-Heterocyclic Carbene Catalysis with Click Chemistry: A Facile One-Pot Approach to 1,2,3-Triazole Derivatives

A combination of the oxidative N-heterocyclic carbene catalysis and click chemistry has been explored for the direct, one-pot synthesis of 1,2,3-triazole derivatives from aromatic aldehydes. This procedure was found to be very efficient and a variety of 1,2,3-triazole derivatives could be accessed through their corresponding propargyl esters in moderate-to-good yields under mild conditions.