Cooperative Activation of Alkyne and Thioamide Functionalities; Direct Catalytic Asymmetric Conjugate Addition of Terminal Alkynes to α,β-Unsaturated Thioamides

Enantioselective Synthesis of a GPR40 Agonist AMG 837 via Catalytic Asymmetric Conjugate Addition of Terminal Alkyne to α,β-Unsaturated Thioamide

(2011) Ryo Yazaki et al.   ORGANIC LETTERS

The Development of Catalytic Nucleophilic Additions of Terminal Alkynes in Water†

(2010) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Rhodium-catalyzed asymmetric conjugate alkynylation of nitroalkenes

(2010) Takahiro Nishimura et al.   CHEMICAL COMMUNICATIONS

Kinetic Isotope Effects in Asymmetric Reactions

(2010) Thomas Giagou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct Catalytic Asymmetric Addition of Allyl Cyanide to Ketones via Soft Lewis Acid/Hard Brønsted Base/Hard Lewis Base Catalysis

(2010) Ryo Yazaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Catalytic Asymmetric Conjugate Addition of Terminal Alkynes to α,β-Unsaturated Thioamides

(2010) Ryo Yazaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Suitable Salt Form for a GPR40 Receptor Agonist

(2010) Henry Morrison et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Asymmetric Cooperative Catalysis of Strong Bronsted Acid-Promoted Reactions Using Chiral Ureas

(2010) H. Xu et al.   SCIENCE

Asymmetric syntheses of a GPR40 receptor agonist via diastereoselective and enantioselective conjugate alkynylation

(2010) Jacqueline C.S. Woo et al.   TETRAHEDRON

Direct catalytic asymmetric aldol reaction of thioamides: a concise asymmetric synthesis of (R)-fluoxetine

(2010) Mitsutaka Iwata et al.   TETRAHEDRON-ASYMMETRY

The Enantioselective Addition of Alkyne Nucleophiles to Carbonyl Groups

(2009) Barry M. Trost et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Counteranion-Directed Transition-Metal Catalysis: Enantioselective Epoxidation of Alkenes with Manganese(III) Salen Phosphate Complexes

(2009) Saihu Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Axial Chirality Control of Gold(biphep) Complexes by Chiral Anions: Application to Asymmetric Catalysis

(2009) Kohsuke Aikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Catalytic Asymmetric Mannich-Type Reaction of Thioamides

(2009) Yuta Suzuki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of β-Alkynyl Aldehydes by Rhodium-Catalyzed Conjugate Alkynylation

(2009) Takahiro Nishimura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold(I)-Catalyzed Enantioselective Synthesis of Pyrazolidines, Isoxazolidines, and Tetrahydrooxazines

(2009) R. L. LaLonde et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Powerful Chiral Counteranion Motif for Asymmetric Catalysis

(2009) Pilar García-García et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonlinear Effects in Asymmetric Catalysis

(2009) Tummanapalli Satyanarayana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral anion-mediated asymmetric ion pairing chemistry

(2009) Jérôme Lacour et al.   CHEMICAL COMMUNICATIONS

Progress in the discovery and development of small-molecule modulators of G-protein-coupled receptor 40 (GPR40/FFA1/FFAR1): an emerging target for type 2 diabetes

(2009) Sandip B Bharate et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Cu(I)-Catalyzed Diamination of Conjugated Olefins with Tunable Anionic Counterions. A Possible Approach to Asymmetric Diamination

(2009) Baoguo Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanism of Amido-Thiourea Catalyzed Enantioselective Imine Hydrocyanation: Transition State Stabilization via Multiple Non-Covalent Interactions

(2009) Stephan J. Zuend et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Catalytic Asymmetric Aldol Reactions of Thioamides: Toward a Stereocontrolled Synthesis of 1,3-Polyols

(2009) Mitsutaka Iwata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Rhodium-Catalyzed Conjugate Alkynylation of 5-Benzylidene Meldrum’s Acids with TMS-acetylene

(2009) Eric Fillion et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Catalytic Asymmetric Addition of Allyl Cyanide to Ketones

(2009) Ryo Yazaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Practical Asymmetric Conjugate Alkynylation of Meldrum’s Acid-Derived Acceptors: Access to Chiral β-Alkynyl Acids

(2009) Sheng Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scaleable catalytic asymmetric Strecker syntheses of unnatural α-amino acids

(2009) Stephan J. Zuend et al.   NATURE

Rhodium-Catalyzed Asymmetric Conjugate Alkynylation of Enones with Alkynylsilanols

(2009) Takahiro Nishimura et al.   ORGANIC LETTERS

Ni(II)-Catalyzed Enantioselective Conjugate Addition of Acetylenes to α,β-Enones

(2009) Oleg V. Larionov et al.   ORGANIC LETTERS

Bifunctional Asymmetric Catalysis: Cooperative Lewis Acid/Base Systems

(2008) Daniel H. Paull et al.   ACCOUNTS OF CHEMICAL RESEARCH

Lewis Base Assisted Brønsted Base Catalysis: Bidentate Phosphine Oxides as Activators and Modulators of Brønsted Basic Lanthanum-Aryloxides

(2008) Hiroyuki Morimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lewis Base Catalysis in Organic Synthesis

(2008) Scott E. Denmark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multimetallic Bifunctional Asymmetric Catalysis Based on Proximity Effect Control

(2008) Shigeki Matsunaga et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS

Chiral Anion-Mediated Asymmetric Ring Opening ofmeso-Aziridinium and Episulfonium Ions

(2008) Gregory L. Hamilton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Steric Tuning of Silylacetylenes and Chiral Phosphine Ligands for Rhodium-Catalyzed Asymmetric Conjugate Alkynylation of Enones

(2008) Takahiro Nishimura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Catalytic Asymmetric Addition of Allylic Cyanides to Ketoimines

(2008) Ryo Yazaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Thiourea-Catalyzed Additions to Oxocarbenium Ions

(2008) Sarah E. Reisman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Michael addition of nitroalkanes to nonactivated α,β-unsaturated δ-thiolactams: reactivity, diastereoselectivity, and comparison to α,β-unsaturated δ-lactams

(2008) Jacek G. Sośnicki   TETRAHEDRON

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Counteranion-Directed Catalysis for the Epoxidation of Enals

(2007) Xingwang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalysed asymmetric Mannich reactions

(2007) Jorge M. M. Verkade et al.   CHEMICAL SOCIETY REVIEWS