Journal
CHEMISTRY-AN ASIAN JOURNAL
Volume 5, Issue 6, Pages 1274-1289Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/asia.201000010
Keywords
flow chemistry; high-temperature chemistry; microreactors; process intensification; synthetic methods
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Funding
- Christian Doppler Society (CDG)
- Higher Education Commission of Pakistan
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Microreactor technology and continuous flow processing in general are key features in making organic synthesis both more economical and environmentally friendly. When preformed under a high-temperature/pressure process intensification regime many transformations originally not considered suitable for flow synthesis owing to long reaction times can be converted into high-speed flow chemistry protocols that can operate at production-scale quantities. This Focus Review summarizes the state of the art in high-temperature/pressure microreactor technology and provides a survey of successful applications of this technique from the recent synthetic organic chemistry literature.
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