Alpha-, Delta- and PP-cells

Pancreatic polypeptide regulates glucagon release through PPYR1 receptors expressed in mouse and human alpha-cells

(2015) F. Aragón et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program

(2014) Tao Gao et al.   Cell Metabolism

Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet

(2014) J. Molina et al.   DIABETES

Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature

(2014) Jiun T. Low et al.   DIABETOLOGIA

Na+current properties in islet α- and β-cells reflect cell-specificScn3aandScn9aexpression

(2014) Quan Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

(2014) Melissa F. Brereton et al.   Nature Communications

Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

(2013) Quan Zhang et al.   Cell Metabolism

Conversion of Mature Human  -Cells Into Glucagon-Producing  -Cells

(2013) H. S. Spijker et al.   DIABETES

Glucose regulation of glucagon secretion

(2013) Erik Gylfe et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Quantitative Analysis of Pancreatic Polypeptide Cell Distribution in the Human Pancreas

(2013) Xiaojun Wang et al.   PLoS One

The Inactivation of Arx in Pancreatic α-Cells Triggers Their Neogenesis and Conversion into Functional β-Like Cells

(2013) Monica Courtney et al.   PLoS Genetics

SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells

(2012) Balrik Kailey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets

(2012) P. Marchetti et al.   DIABETOLOGIA

Unraveling oxyntomodulin, GLP1's enigmatic brother

(2012) Alessandro Pocai   JOURNAL OF ENDOCRINOLOGY

Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut–brain axis

(2012) Peter Holzer et al.   NEUROPEPTIDES

β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition

(2011) Catherine A. Jurgens et al.   AMERICAN JOURNAL OF PATHOLOGY

Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas

(2011) Rayner Rodriguez-Diaz et al.   Cell Metabolism

Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice

(2011) Y. Lee et al.   DIABETES

Novel insight into glucagon receptor action: lessons from knockout and transgenic mouse models

(2011) P. M. Vuguin et al.   DIABETES OBESITY & METABOLISM

Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?

(2011) J. N. Walker et al.   DIABETES OBESITY & METABOLISM

Pancreatic alpha cell mass in European subjects with type 2 diabetes

(2011) J. C. Henquin et al.   DIABETOLOGIA

Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas

(2011) M. J. Riedel et al.   DIABETOLOGIA

Context-specific  -to- -cell reprogramming by forced Pdx1 expression

(2011) Y.-P. Yang et al.   GENES & DEVELOPMENT

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

(2011) Rayner Rodriguez-Diaz et al.   NATURE MEDICINE

Altered Islet Composition and Disproportionate Loss of Large Islets in Patients with Type 2 Diabetes

(2011) German Kilimnik et al.   PLoS One

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans

(2011) Patrik Rorsman et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

(2010) Yang Z. De Marinis et al.   Cell Metabolism

Unique Arrangement of  - and  -Cells in Human Islets of Langerhans

(2010) D. Bosco et al.   DIABETES

Glucose-responsive beta cells in islets isolated from a patient with long-standing type 1 diabetes mellitus

(2010) J. N. Walker et al.   DIABETOLOGIA

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Somatostatin Receptor Subtypes in Human Type 2 Diabetic Islets

(2010) Guida M. Portela-Gomes et al.   PANCREAS

Paracrinology of islets and the paracrinopathy of diabetes

(2010) R. H. Unger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells

(2009) M. Braun et al.   DIABETOLOGIA

The Glucagon Receptor Is Required for the Adaptive Metabolic Response to Fasting

(2008) Christine Longuet et al.   Cell Metabolism

Somatostatin Secreted by Islet  -Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function

(2008) A. C. Hauge-Evans et al.   DIABETES

Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets

(2008) Lara R. Nyman et al.   JOURNAL OF CLINICAL INVESTIGATION

KATP-channels and glucose-regulated glucagon secretion

(2008) Patrik Rorsman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM