Synthesis of (±)-Spongiolactone Enabling Discovery of a More Potent Derivative

A Diastereoselective, Nucleophile-Promoted Aldol-Lactonization of Ketoacids Leading to Bicyclic-β-Lactones

(2012) Gang Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective, Organocatalyzed, Intramolecular Aldol Lactonizations with Keto Acids Leading to Bi- and Tricyclic β-Lactones and Topology-Morphing Transformations

(2010) Carolyn A. Leverett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A1,3-strain enabled retention of chirality during bis-cyclization of β-ketoamides: total synthesis of (−)-salinosporamide A and (−)-homosalinosporamide A

(2010) Henry Nguyen et al.   CHEMICAL COMMUNICATIONS

Acylating drugs: redesigning natural covalent inhibitors

(2010) Arthur F Kluge et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bioinspired Total Synthesis and Human Proteasome Inhibitory Activity of (−)-Salinosporamide A, (−)-Homosalinosporamide A, and Derivatives Obtained via Organonucleophile Promoted Bis-cyclizations

(2010) Henry Nguyen et al.   JOURNAL OF ORGANIC CHEMISTRY

Double Diastereoselective, Nucleophile-Catalyzed Aldol Lactonizations (NCAL) Leading to β-Lactone Fused Carbocycles and Extensions to β-Lactone Fused Tetrahydrofurans

(2010) Kay A. Morris et al.   ORGANIC LETTERS

Bioactive Diterpene Derivatives from the Marine SpongeSpongionellasp.

(2009) Mostafa E. Rateb et al.   JOURNAL OF NATURAL PRODUCTS

Asymmetric Synthesis, Structure, and Reactivity of Unexpectedly Stable Spiroepoxy-β-Lactones Including Facile Conversion to Tetronic Acids: Application to (+)-Maculalactone A

(2009) Richard J. Duffy et al.   JOURNAL OF ORGANIC CHEMISTRY

β-Lactones as Privileged Structures for the Active-Site Labeling of Versatile Bacterial Enzyme Classes

(2008) Thomas Böttcher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

LiCl-Mediated Preparation of Highly Functionalized Benzylic Zinc Chlorides

(2008) Albrecht Metzger et al.   ORGANIC LETTERS

Highly Diastereoselective Addition of Cinnamylzinc Derivatives to α-Chiral Carbonyl Compounds

(2007) Guillaume Dunet et al.   ORGANIC LETTERS