Tetrafluorination of Sugars as Strategy for Enhancing Protein-Carbohydrate Affinity: Application to UDP-GalpMutase Inhibition

Development of fucosyltransferase and fucosidase inhibitors

(2013) Zhijay Tu et al.   CHEMICAL SOCIETY REVIEWS

[18F]-5-Fluoro-5-deoxyribose, an efficient peptide bioconjugation ligand for positron emission tomography (PET) imaging

(2012) Xiang-Guo Li et al.   CHEMICAL COMMUNICATIONS

Multivalent glycoconjugates as anti-pathogenic agents

(2012) Anna Bernardi et al.   CHEMICAL SOCIETY REVIEWS

Reversible and Efficient Inhibition of UDP-Galactopyranose Mutase by Electrophilic, Constrained and Unsaturated UDP-Galactitol Analogues

(2012) Christophe Ansiaux et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identification of the NAD(P)H Binding Site of Eukaryotic UDP-Galactopyranose Mutase

(2012) Richa Dhatwalia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Mechanism of UDP-Galactopyranose Mutase from Trypanosoma cruzi: A Potential Drug Target against Chagas' Disease

(2012) Michelle Oppenheimer et al.   PLoS One

Tailoring the Specificity and Reactivity of a Mechanism-Based Inactivator of Glucocerebrosidase for Potential Therapeutic Applications

(2011) Brian P. Rempel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs

(2011) Muthiah Manoharan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The conformation of tetrafluorinated methyl galactoside anomers: crystallographic and NMR studies

(2011) Bruno Linclau et al.   CARBOHYDRATE RESEARCH

Chemistry and glycobiology

(2011) Chung-Yi Wu et al.   CHEMICAL COMMUNICATIONS

Heavily fluorinated carbohydrates as enzyme substrates: oxidation of tetrafluorinated galactose by galactose oxidase

(2011) Avgousta Ioannou et al.   CHEMICAL COMMUNICATIONS

Carbohydrate-mimetic peptides: structural aspects of mimicry and therapeutic implications

(2011) Mark Agostino et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase

(2011) He G. Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the “Hydrophobic Wall” of Carbonic Anhydrase

(2011) Jasmin Mecinović et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorine-Protein Interactions and 19F NMR Isotropic Chemical Shifts: An Empirical Correlation with Implications for Drug Design

(2010) Claudio Dalvit et al.   ChemMedChem

Chemistry and Biology of Galactofuranose-Containing Polysaccharides

(2009) Michele R. Richards et al.   CHEMBIOCHEM

Recent advances in mycobacterial cell wall glycan biosynthesis

(2009) Pui-Hang Tam et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis of ThreeC-Glycoside Analogues of UDP-Galactopyranose as Conformational Probes for the Mutase-Catalyzed Furanose/Pyranose Interconversion

(2009) Audrey Caravano et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Characterization of a Bifunctional Pyranose-Furanose Mutase fromCampylobacter jejuni11168

(2009) Myles B. Poulin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Group epitope mapping considering relaxation of the ligand (GEM-CRL): Including longitudinal relaxation rates in the analysis of saturation transfer difference (STD) experiments

(2009) Sebastian Kemper et al.   JOURNAL OF MAGNETIC RESONANCE

Sugar nucleotide recognition by Klebsiella pneumoniae UDP-d-galactopyranose mutase: Fluorinated substrates, kinetics and equilibria

(2009) James C. Errey et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Probing UDP-galactopyranose mutase binding pocket: A dramatic effect on substitution of the 6-position of UDP-galactofuranose

(2008) Guillaume Eppe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

19F NMR applications in chemical biology

(2008) Steven L. Cobb et al.   JOURNAL OF FLUORINE CHEMISTRY

Investigation of Binding of UDP-Galfand UDP-[3-F]Galfto UDP-galactopyranose Mutase by STD-NMR Spectroscopy, Molecular Dynamics, and CORCEMA-ST Calculations†

(2008) Yue Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibitors of UDP-Galactopyranose Mutase Thwart Mycobacterial Growth

(2008) Emily C. Dykhuizen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Tetrafluorinated Glucose and Galactose

(2008) Roxana S. Timofte et al.   ORGANIC LETTERS

Substrate directs enzyme dynamics by bridging distal sites: UDP-galactopyranose mutase

(2008) Xiaohui Yao et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS