Synthesis and Some Biological Properties of Pyrrolo[1,2-a]indoles

Acitretin

(2015) Noelani E. Gonzalez Ortiz et al.   Dermatologic Therapy

Highly Enantioselective Friedel-Crafts Alkylation/N-Hemiacetalization Cascade Reaction with Indoles

(2013) Hong-Gang Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu(OTf)2 catalysed [6+2] cycloaddition reaction for the synthesis of highly substituted pyrrolo[1,2-a]indoles: rapid construction of the yuremamine core

(2013) Dattatraya H. Dethe et al.   CHEMICAL COMMUNICATIONS

Palladium–copper-cocatalyzed intramolecular oxidative coupling: an efficient and atom-economical strategy for the synthesis of 3-acylindoles

(2013) Xiao-Feng Xia et al.   CHEMICAL COMMUNICATIONS

Barton esters for initiator-free radical cyclisation with heteroaromatic substitution

(2013) Robert Coyle et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Manganese-catalyzed aerobic dehydrogenative cyclization toward ring-fused indole skeletons

(2013) Kounosuke Oisaki et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Gold(I)-Catalyzed Rearrangement of N-Aryl 2-Alkynylazetidines to Pyrrolo[1,2-a]indoles

(2013) Nicolas Kern et al.   ORGANIC LETTERS

Pd(II)-catalyzed intramolecular aminopalladation/direct C–H arylation under aerobic conditions: synthesis of pyrrolo[1,2-a]indoles

(2013) Tiffany Piou et al.   TETRAHEDRON

Pd(II)-catalyzed aerobic oxidative intramolecular hydroamination and C–H functionalization of N-alkynyl anilines for the synthesis of indole derivatives

(2013) Long Ren et al.   TETRAHEDRON

Expeditious Synthesis of Tetrasubstituted Helical Alkenes by a Cascade of Palladium-Catalyzed CH Activations

(2012) Hongqiang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease

(2012) Daniel J. Buzard et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thermally induced [3+2] cyclization of aniline-tethered alkylidenecyclopropanes: a facile synthetic protocol of pyrrolo[1,2-a]indoles

(2012) Kai Chen et al.   CHEMICAL COMMUNICATIONS

Indole Synthesis by Conjugate Addition of Anilines to Activated Acetylenes and an Unusual Ligand-Free Copper(II)-Mediated Intramolecular Cross-Coupling

(2012) Detian Gao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemoselective Intramolecular Alkylation of the Blaise Reaction Intermediates: Tandem One-Pot Synthesis of exo-Cyclic Enaminoesters and Their Applications toward the Synthesis of N-Heterocyclic Compounds

(2012) Ju Hyun Kim et al.   JOURNAL OF ORGANIC CHEMISTRY

Complementary Asymmetric Routes to (R)-2-(7-Hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate

(2012) Thomas O. Schrader et al.   ORGANIC LETTERS

Formal Synthesis of 7-Methoxymitosene and Synthesis of its Analog via a Key PtCl2-Catalyzed Cycloisomerization

(2012) Lianzhu Liu et al.   ORGANIC LETTERS

Palladium-Catalyzed Direct Arylation for the Synthesis of Indeno[2,1-b]-pyrrol-8-ones

(2012) Junbiao Chang et al.   SYNLETT

Aerobic Palladium(II)-Catalyzed 5-endo-trig Cyclization: An Entry into the Diastereoselective C-2 Alkenylation of Indoles with Tri- and Tetrasubstituted Double Bonds

(2011) Sandeep R. Kandukuri et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed Bicylization to the Mitosene Skeleton

(2011) Hye-Young Pyeon et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

N-Fused Indolines through Non-Carbonyl-Stabilized Rhodium Carbenoid CH Insertion of N-Aziridinyl Imines

(2011) Stuart J. Mahoney et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of 9,9-Disubstituted 9H-Pyrrolo[1,2-a]indoles by Hydriodic Acid-Catalyzed Cyclization of 1-[2-(1-Aryl(or methyl)ethenyl)phenyl]-1H-pyrroles

(2011) Kazuhiro Kobayashi et al.   HELVETICA CHIMICA ACTA

Design and synthesis of novel polycycles based on the 3H-pyrrolo/6,7-dihydropyrido[1,2-a]indole scaffold as templates for pharmaceutical development

(2011) Marco Derudas et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Biomimetic Total Syntheses of Flinderoles B and C

(2011) Dattatraya H. Dethe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CH activation and CH2 double activation of indolines by radical translocation: Understanding the chemistry of the indolinyl radical

(2011) David C. Harrowven et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Photoinduced chlorine atom-transfer cyclization/photohydrolysis of 3-acyl-2-chloro-N-(ω-phenylalkynyl)pyrroles: a one-pot synthesis of benzoyl-substituted fused pyrroles

(2011) Shen-Ci Lu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Diastereoselective Intramolecular Friedel–Crafts Cyclizations of Substituted Methyl 2-(1H-indole-1-carbonyl)acrylates: Efficient Access to Functionalized 1H-Pyrrolo[1,2-a]indoles

(2011) Dadasaheb V. Patil et al.   ORGANIC LETTERS

Palladium-Catalyzed Intramolecular Trapping of the Blaise Reaction Intermediate for Tandem One-Pot Synthesis of Indole Derivatives

(2011) Ju Hyun Kim et al.   ORGANIC LETTERS

Reaction of α-chloro-β-oxobutanal with indole derivatives

(2011) M. A. Allakhverdiev et al.   RUSSIAN JOURNAL OF APPLIED CHEMISTRY

One-Pot Organocatalytic Asymmetric Synthesis of 1H-Pyrrolo[1,2a]indol-3(2H)-ones via a Michael-Hemiaminalization-Oxidation Sequence

(2011) Dieter Enders et al.   SYNLETT

[3+2] Cycloaddition of metal-containing azomethine ylides for highly efficient synthesis of mitosene skeleton

(2011) Jun Takaya et al.   TETRAHEDRON

Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids

(2011) Francesca Aiello et al.   TETRAHEDRON LETTERS

Chemoselective Cascade Synthesis of N-Fused Heterocycles via Silver(I) Triflate-Catalyzed Friedel-Crafts/N-C Bond Formation Sequence

(2010) Lu Hao et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Intramolecular Aza-Michael Additions of Indoles Catalyzed by Chiral Phosphoric Acids

(2010) Quan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Indoles by Conjugate Addition and Ligand-Free Copper-Catalyzed Intramolecular Arylation of Activated Acetylenes with o-Haloanilines

(2010) Detian Gao et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene Catalyzed Domino Reactions of Formylcyclopropane 1,1-Diesters: Construction of a 6-5-5 Tricyclic Pyrrolo[1,2-a]indole

(2010) Linxia Li et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Cyclocoupling of 2-Halobiaryls with Isocyanides via the Cleavage of Carbon−Hydrogen Bonds

(2010) Mamoru Tobisu et al.   JOURNAL OF ORGANIC CHEMISTRY

Iodine-Mediated Synthesis of 3H-Indoles via Intramolecular Cyclization of Enamines

(2010) Zhiheng He et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Brønsted acid catalyzed asymmetric Friedel–Crafts alkylation reaction of indoles with α,β-unsaturated ketones: short access to optically active 2- and 3-substituted indole derivatives

(2010) Tsubasa Sakamoto et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

One-pot highly efficient synthesis of substituted pyrroles and N-bridgehead pyrroles by zinc-catalyzed multicomponent reaction

(2010) Xiao-tao Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Visible Light-Mediated Intermolecular C−H Functionalization of Electron-Rich Heterocycles with Malonates

(2010) Laura Furst et al.   ORGANIC LETTERS

Direct cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids into fused pyrrolizinones

(2010) Francesca Aiello et al.   TETRAHEDRON LETTERS

Expedient Synthesis of N-Fused Indoles: A CF Activation and CH Insertion Approach

(2009) Kohei Fuchibe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic N-Alkylation of Indole-2-carbaldehydes with α,β-Unsaturated Aldehydes: One-Pot Synthesis of Chiral Pyrrolo[1,2-a]indole-2-carbaldehydes

(2009) Liang Hong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer

(2009) Dimitra Hadjipavlou-Litina et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Fujiwara-Moritani Indole and Pyrrole Annulations Catalyzed by Chiral Palladium(II)-NicOx Complexes

(2009) Julia A. Schiffner et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

1,2,3,9-Tetrahydro-4H-carbazol-4-one and 8,9-dihydropyrido-[1,2-a]indol-6(7H)-one from 1H-indole-2-butanoic acid

(2009) Richard A. Bunce et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Electron Transfer Photoredox Catalysis: Intramolecular Radical Addition to Indoles and Pyrroles

(2009) Joseph W. Tucker et al.   ORGANIC LETTERS

Efficient synthesis of 9H-pyrrolo[1,2-a]indol-9-one derivatives based on active manganese dioxide promoted intramolecular cyclization

(2009) Francesca Aiello et al.   TETRAHEDRON

Platinum-Catalyzed Formation of Cyclic-Ketone-Fused Indoles fromN-(2-Alkynylphenyl)lactams

(2007) Guotao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION